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Central nervous system varicella zoster vasculopathy in an immunocompromised patient
ConclusionThis clinical case and review of the literature highlights the challenges in the diagnosis and management of VZV CNS vasculopathy in immunocompromised patients.
Source: IDCases - December 29, 2018 Category: Infectious Diseases Source Type: research

Clinical Use of the Amplatzer Device in the Management of Intracardiac Defects: A Single-Center Experience
Int J Angiol DOI: 10.1055/s-0038-1626718Device therapy is a viable alternative to open heart surgery in the management of intracardiac defects. The Amplatzer septal occluder (ASO) is one such device that has been adapted to close a wide variety of cardiac defects with few complications and a high success rate. This is a retrospective review of all the patients who received the ASO between 2012 and 2016 at the University of Kentucky. In total, 169 patients underwent percutaneous closure of a septal defect with Amplatzer during the timeframe studied, and of those, 91% received the device for an atrial septal defect or patent...
Source: International Journal of Angiology - January 30, 2018 Category: Cardiology Authors: Rao, Seema S. Scaff, Tyler L. Gurley, John Saha, Sibu Tags: Original Article Source Type: research

Abstract 150: Machine Learning Methodology Predicts Comorbidities are Associated With Increased Total Healthcare Costs Among Patients With Severe Peripheral Artery Disease Session Title: Poster Session II
Conclusion: In this study, the presence of chronic ulcers in the lower extremities and CKD were two factors most predictive of increased all-cause total HC in a geographically diverse population of severe PAD patients.
Source: Circulation: Cardiovascular Quality and Outcomes - March 31, 2017 Category: Cardiology Authors: Berger, J. S., Haskell, L., Ting, W., Lurie, F., Eapen, Z., Valko, M., Alas, V., Rich, K., Crivera, C., Schein, J. Tags: Session Title: Poster Session II Source Type: research

Rapidly progressive bilateral optic nerve and retinal infarctions due to rhinocerebral mucormycosis and pseudoephedrine use
We report rapidly progressive bilateral visual loss from mucormycosis due to bilateral optic nerve and retinal infarction in a patient with diabetes.1
Source: Neurology Clinical Practice - December 11, 2016 Category: Neurology Authors: Merkler, A. E., Duggal, I., Kaunzner, U., Maciel, C. B., Miller, A. M., Scognamiglio, T., Dinkin, M. J. Tags: MRI, Other cerebrovascular disease/ Stroke, Fungal infections, Clinical neurology examination, Visual loss Case Source Type: research

Cavernous Sinus Thrombosis in Children: Imaging Characteristics and Clinical Outcomes Brief Reports
Conclusions— CAN and infarcts were common in this modest cohort of children with CST. Despite the high incidence of CAN and infarction, outcomes were often favorable. Although this is the largest cohort of childhood CST reported to date, large multicenter cohorts are needed to confirm our findings and determine the preferred therapeutic strategies for childhood CST.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Press, C. A., Lindsay, A., Stence, N. V., Fenton, L. Z., Bernard, T. J., Mirsky, D. M. Tags: Computerized tomography and Magnetic Resonance Imaging, Anticoagulants, Antiplatelets Brief Reports Source Type: research

Understanding and Communicating the Benefits and Risks of Denosumab, Raloxifene, and Teriparatide for the Treatment of Osteoporosis
The number needed to treat is a valuable metric to determine the benefit of therapy, but it must be viewed against the respective number needed to harm. Denosumab and teriparatide (TPTD) have proven antifracture efficacy at vertebral and nonvertebral sites, whereas raloxifene has proven antifracture efficacy at the spine only. Denosumab use has been associated with a small, yet statistically significant, increased incidence of eczema and serious cellulitis. Raloxifene use has been associated with statistically significant increases in the risk of venous thromboembolism and possibly deadly stroke, although not an increase in total strokes.
Source: Journal of Clinical Densitometry - October 28, 2013 Category: Radiology Authors: E. Michael Lewiecki, Paul D. Miller, Steve T. Harris, Douglas C. Bauer, K. Shawn Davison, Larry Dian, David A. Hanley, Michael R. McClung, Chui K. Yuen, David L. Kendler Source Type: research

Adverse Outcomes Associated With Elective Knee Arthroscopy: A Population-Based Cohort Study
Conclusions: Our study found 6.4 adverse outcomes per 1,000 elective knee arthroscopy procedures (0.64%), with the 3 most common complications being DVT, effusion and synovitis, and PE. We have also identified risk factors for adverse outcomes, particularly chronic kidney disease, myocardial infarction, cerebrovascular accident, and cancer.Level of Evidence: Level III, retrospective cohort study.
Source: Arthroscopy - February 8, 2013 Category: Surgery Authors: Megan A. Bohensky, Richard deSteiger, Chris Kondogiannis, Vijaya Sundararajan, Nick Andrianopoulos, Andrew Bucknill, Geoffrey McColl, Caroline A. Brand Tags: Original Articles Source Type: research

Infectious Diseases: Images in Clinical Medicine
Editor: V. Dimov, M.D., Cleveland ClinicHypoglossal Nerve Palsy during Meningococcal Meningitis. NEJM, 10/2014.Herpes Zoster Involving the S1 Dermatome. NEJM, 05/2014.Tinea Faciei. NEJM, 05/2014.Disseminated Cryptococcosis in a CLL patient. 05/2014.Scrofuloderma due to Mycobacterium tuberculosis. NEJM, 06/2012.Leonine Facies in Lepromatous Leprosy. NEJM, 04/2012.Intestinal Infestation with Ancylostoma ceylanicum. NEJM, 03/2012.Kerion celsi form of tinea capitis caused by a T-cell hypersensitivity reaction. NEJM, 03/2012.Eye can see a nest of worms! Thelazia callipaeda. Lancet, 03/2012.Madura Foot. NEJM, 01/2012.Paragonimia...
Source: Clinical Cases and Images - August 22, 2009 Category: General Medicine Tags: Images Infectious Diseases Source Type: news

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