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Specialty: Neurology
Source: Neurological Research
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Total 488 results found since Jan 2013.
Anterior circulation large vessel occlusion outcomes in patients transferred from a peripheral primary stroke centre
DISCUSSION: Outcomes depended on stroke severity, age and vessel of occlusion. Prognosis was worse if the occlusion included M1, especially in octogenarians. Mothership and Drip-n-ship strategies should be compared in patients from remote locations stratified by stroke severity and patient age.PMID:34986748 | DOI:10.1080/01616412.2021.2024727
Source: Neurological Research - January 6, 2022 Category: Neurology Authors: Jussi O T Sipil รค Source Type: research
Novel predictors and a predictive model of cerebrovascular atherosclerotic ischemic stroke based on clinical databases
CONCLUSION: The efficacy of the predictive model was acceptable as an aid in predicting cerebrovascular atherosclerotic ischemic stroke.PMID:36413433 | DOI:10.1080/01616412.2022.2149185
Source: Neurological Research - November 22, 2022 Category: Neurology Authors: He Li Pei Liu Hong-Yu Ma Wei-Long Hua Yong-Xin Zhang Lei Zhang Yong-Wei Zhang Bo Hong Peng-Fei Yang Jian-Min Liu Source Type: research
The association of stroke risk factors with the future thickness of carotid atherosclerotic plaques
DISCUSSION: The effect of each predictor on plaque thickness is complicated by interactions with other risk factors, particularly for the left carotid artery. The side of carotid artery involvement should be considered for stroke prevention.PMID:37125820 | DOI:10.1080/01616412.2023.2208484
Source: Neurological Research - May 1, 2023 Category: Neurology Authors: Tanya Mohammadi Zahra Hooshanginezhad Babak Mohammadi Sina Dolatshahi Source Type: research
Neuroprotection by peripheral nerve electrical stimulation and remote postconditioning against acute experimental ischaemic stroke.
DISCUSSION: Peripheral nerve ES appears to have a neuroprotective effect in a rat dMCAO model. This effect may indicate a neural protective mechanism underlying beneficial effect of RIPostC.
PMID: 25819636 [PubMed - as supplied by publisher]
Source: Neurological Research - March 31, 2015 Category: Neurology Tags: Neurol Res Source Type: research
Pharmacological hypothermia: a potential for future stroke therapy?
Authors: Liu K, Khan H, Geng X, Zhang J, Ding Y
Abstract
Mild physical hypothermia after stroke has been associated with positive outcomes. Despite the well-studied beneficial effects of hypothermia in the treatment of stroke, lack of precise temperature control, intolerance for the patient, and immunosuppression are some of the reasons which limit its clinical translation. Pharmacologically induced hypothermia has been explored as a possible treatment option following stroke in animal models. Currently, there are eight classes of pharmacological agents/agonists with hypothermic effects affecting a multitude of sys...
Source: Neurological Research - June 21, 2016 Category: Neurology Tags: Neurol Res Source Type: research
Role of Interleukin-10 (-1082A/G) gene polymorphism with the risk of ischemic stroke: a meta-analysis.
Authors: Kumar P, Yadav AK, Misra S, Kumar A, Chakravarty K, Prasad K
Abstract
The role of anti-inflammatory Interleukin-10 (IL-10) cytokine gene polymorphism with the risk of ischemic stroke (IS) remains controversial. The aim of present meta-analysis was to investigate the association of IL-10 (-1082 A/G) gene polymorphism with the risk of IS. A literature search for candidate gene association studies published before 29 February 2016 was conducted in the PubMed, EMBASE, Google Scholar, and TRIP database. The following search terms were used: 'Interleukin-10' or 'IL-10' and 'Ischemic stroke' or 'IS' and 'Cerebral...
Source: Neurological Research - July 3, 2016 Category: Neurology Tags: Neurol Res Source Type: research
Neuroprotective effect of epidermal growth factor plus growth hormone-releasing peptide-6 resembles hypothermia in experimental stroke.
DISCUSSION: With hypothermia being a good standard neuroprotectant reference, these results provide additional proof of principle for EGF and GHRP-6 co-administration as a potentially neuroprotective stroke therapy.
PMID: 27665924 [PubMed - as supplied by publisher]
Source: Neurological Research - September 27, 2016 Category: Neurology Tags: Neurol Res Source Type: research
Effects of different frequencies of repetitive transcranial magnetic stimulation in stroke patients with non-fluent aphasia: a randomized, sham-controlled study.
CONCLUSIONS: LF-rTMS and HF-rTMS are both beneficial to the recovery of linguistic function in patients with post-stroke non-fluent aphasia. LF-rTMS produced immediate benefits that persisted long-term, while HF-rTMS only produced long-term benefits. In addition, the benefits produced with LF-rTMS were more marked than those produced by HF-rTMS.
PMID: 29589518 [PubMed - as supplied by publisher]
Source: Neurological Research - March 30, 2018 Category: Neurology Tags: Neurol Res Source Type: research
Argatroban plus aspirin versus aspirin in acute ischemic stroke.
CONCLUSION: Argatroban is effective and safe for the treatment of moderate AIS with similar efficacy to high-dose aspirin in the acute phase of AIS, although no additional benefit on short-term outcome was observed. For patients with mild AIS, argatroban may be inferior to high-dose aspirin.
PMID: 30052164 [PubMed - as supplied by publisher]
Source: Neurological Research - July 30, 2018 Category: Neurology Tags: Neurol Res Source Type: research
Percutaneous mastoid electrical stimulator alleviates autonomic dysfunction in patients with acute ischemic stroke.
CONCLUSIONS: PMES was a safe, effective, and low-cost therapy to alleviate HRV and could significantly reduce mortality in the early recovery phase after acute ischemic stroke.
PMID: 30111262 [PubMed - as supplied by publisher]
Source: Neurological Research - August 18, 2018 Category: Neurology Tags: Neurol Res Source Type: research
Predictors of mortality and recurrent stroke within five years of intracerebral hemorrhage.
Conclusion Predictors of recurrent stroke were older females, hypertension, diabetes, and brain stem hemorrhage. These findings may help to determine specific treatment strategies and improve quality of health care for such patients.
PMID: 30134784 [PubMed - in process]
Source: Neurological Research - August 25, 2018 Category: Neurology Tags: Neurol Res Source Type: research
The relationship between brain microbleeds and homeostatic markers in the treatment of ischemic stroke.
CONCLUSION: Pathogenesis of AF is involved abnormal changes of hemostasis, endothelial dysfunction, antithrombotic state and inflammation. The homeostatic markers, which play role in these pathways, and the presence of BMBs could use to form a prognostic clinic assessment tool to predict bleeding risk.
PMID: 30207930 [PubMed - as supplied by publisher]
Source: Neurological Research - September 14, 2018 Category: Neurology Tags: Neurol Res Source Type: research
Antidepressant-like effects of paeoniflorin on post-stroke depression in a rat model.
CONCLUSIONS: Observed results suggested that paeoniflorin could ameliorate the symptoms and improve the functional capability of PSD rats, similar to the effect of fluoxetine.
ABBREVIATIONS: PSD: post-stroke depression; CUMS: chronic unpredictable mild stress stimulation; MCAO: middle cerebral artery occlusion; OFT: open field test; SPT: sucrose preference test, NDS: neurological deficit score, BBT: beam balance test; BDNF: brain-derived neurotrophic factor protein; p-CREB: phosphorylated Cyclic-AMP responsive element binding protein.
PMID: 30759063 [PubMed - as supplied by publisher]
Source: Neurological Research - February 15, 2019 Category: Neurology Tags: Neurol Res Source Type: research
Exposure to female estrous is beneficial for male mice against transient ischemic stroke.
CONCLUSION: Exposure to female estrous reduces mortality and improves functional recovery in MCAO male mice. The study provides the first evidence to support the importance of female interaction to male stroke rehabilitation.
ABBREVIATIONS: GAP-43: growth-associated protein-43; SYP: Synaptophysin; MCAO: middle cerebral artery occlusion; OVXs: ovariectomies; CCA: common carotid artery; ECA: external carotid artery; EFE: estrous female exposure; TTC: 2,3,5-triphenyltetrazolium chloride; PAGE: polyacrylamide gel electrophoresis; PVDF: polyvinylidene difluoride; ANOVA: analysis of variance; LSD: least significant differenc...
Source: Neurological Research - March 1, 2019 Category: Neurology Tags: Neurol Res Source Type: research
