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One-year outcomes and secondary prevention in patients after acute minor stroke: results from the China National Stroke Registry.
CONCLUSIONS: Outcomes in individuals in China who had experienced acute minor stroke were unfavorable, underscoring the importance of early, sustained preventive therapy in this patient population. Combination of secondary prevention medication classes was associated with a lower risk of death. PMID: 28476094 [PubMed - as supplied by publisher]
Source: Neurological Research - May 11, 2017 Category: Neurology Tags: Neurol Res Source Type: research

Association between socioeconomic status and prognosis after ischemic stroke in South China.
Conclusions: Patients with low income, family caregiver, and no insurance have a poorer prognosis after ischemic stroke that can be partly explained by intermediate variable in the patients' demographic characteristics, cardiovascular disease, behavior lifestyle, and stroke severity. Abbreviations: DALYs: disability-adjusted life years; SES: socioeconomic status; FMC: free medical care; MIUR: medical insurance for urban residents; MIUE: medical insurance for urban employees; NCMS: new rural cooperative medical scheme ; NIHSS: National Institute of Health Stroke Scale ; mRS: modified Rankin scale; OR: odds ratios; CI: confi...
Source: Neurological Research - June 19, 2019 Category: Neurology Tags: Neurol Res Source Type: research

Validation and comparison of prognostic scales in Chinese patients with ischemic stroke: a prospective study from CATIS
CONCLUSION: : The ASTRAL score had higher efficacy than the SPAN-100 and THRIVE scores in predicting 2-year adverse outcomes among Chinese patients with ischemic stroke, suggesting that it could be a valuable risk assessment tool for the 2-year prognosis of such patients.PMID:34431455 | DOI:10.1080/01616412.2021.1959775
Source: Neurological Research - August 25, 2021 Category: Neurology Authors: Kaixin Zhang Zhengbao Zhu Bizhong Che Xiaoqing Bu Tian Xu Chongke Zhong Aili Wang Hao Peng Daoxia Guo Xiaowei Zheng Tan Xu Jing Chen Yonghong Zhang Jiang He Source Type: research

Remote ischemic conditioning with exercise (RICE) promotes functional rehabilitation following ischemic stroke
Conclusions: RICE, a novel therapy that supplements RIC prior to exercise, is superiorly effective in inducing rehabilitation after stroke as compared to the traditional exercise monotherapy rehabilitation in rats with ischemic brain injury.PMID:34151756 | DOI:10.1080/01616412.2021.1939489
Source: Neurological Research - June 21, 2021 Category: Neurology Authors: Qingzhu Wang Melissa Wills Fengwu Li Xiaokun Geng Yuchuan Ding Source Type: research

Antithrombotic therapy for ischaemic stroke patients with AF/RHD in West China daily practice.
CONCLUSION: Our study suggests that overall real-world use of warfarin in IS patients with AF and/or RHD is low before and after admission in West China. Implementation study on this respect should be conducted in this area to improve the daily practice. PMID: 26178783 [PubMed - as supplied by publisher]
Source: Neurological Research - July 17, 2015 Category: Neurology Tags: Neurol Res Source Type: research

Predictors of dependence after MCA ischemic stroke submitted to thrombolysis.
DISCUSSION: .Dependence is an important indicator of the efficacy of stroke care. Besides it was not possible to evaluate rehabilitation, this is the first study on predictors of post-stroke dependence that focus exclusively on patients with first-ever MCA IS submitted to IVT. NIHSS, LAA stroke, in-hospital pneumonia and seizures after discharge were associated with dependence after first-ever MCA IS submitted to IVT. PMID: 29125072 [PubMed - as supplied by publisher]
Source: Neurological Research - November 11, 2017 Category: Neurology Tags: Neurol Res Source Type: research

Association study of CACNA1C polymorphisms with large artery atherosclerotic stroke in Chinese Han population.
Conclusion The results suggested that there was a potential association between CNCNA1C gene and the risk factor of LAA stroke in Chinese Han population. PMID: 29683785 [PubMed - as supplied by publisher]
Source: Neurological Research - April 24, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Effect of renal function on association between uric acid and prognosis in acute ischemic stroke patients with elevated systolic blood pressure.
CONCLUSION: The present study suggests that high serum uric acid concentration is associated with better prognosis in ischemic stroke patients with normal renal function, but not in those with abnormal renal function. The establishment of causality between increased uric acid levels and better stroke prognosis needs more suitably designed randomized clinical trials. PMID: 32657261 [PubMed - as supplied by publisher]
Source: Neurological Research - July 15, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Impact of post-stroke disability and disability-perception on health-related quality of life of stroke survivors: the moderating effect of disability-severity.
CONCLUSION: Significant disability exists among stroke survivors and impaired their HRQoL while disability-severity moderating the effect. More stroke survivors have positive attitude towards their disability and impact positively on their physical health. PMID: 32573376 [PubMed - as supplied by publisher]
Source: Neurological Research - June 25, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Relationship of phosphodiesterase 4D (PDE4D) gene polymorphisms with risk of ischemic stroke: a hospital based case-control study.
CONCLUSION: SNP 83 of PDE4D gene may increase the risk for developing IS whereas SNP 87 and SNP45 of PDE4D may not be associated with the risk of IS in the North Indian population. Prospective cohort studies are required to corroborate these findings. PMID: 28562233 [PubMed - as supplied by publisher]
Source: Neurological Research - June 2, 2017 Category: Neurology Tags: Neurol Res Source Type: research

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