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Source: Neurological Research
Condition: Disability

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Total 71 results found since Jan 2013.

Association of inpatient rehabilitation with functional outcome in patients with stroke receiving mechanical thrombectomy
CONCLUSION: Patients with ischemic stroke who received MT who have a worse disability, particularly at discharge, while undergoing inpatient rehabilitation have higher odds of having poor future functional outcomes. This was regardless of age, sex, or race. Future research is needed to understand the mechanisms that can improve functional performance in our patient population at the IRF.PMID:36646651 | DOI:10.1080/01616412.2023.2167534
Source: Neurological Research - January 16, 2023 Category: Neurology Authors: Chen Lin Andrea Arevalo Hely D Nanavati Source Type: research

A pharmacoeconomic assessment of recombinant tissue plasminogen activator therapy for acute ischemic stroke in a tertiary hospital in China.
Conclusions: Intravenous rt-PA was associated with lower patients' disabilities, fewer in-hospital days, and comparable total costs compared to conservative therapy for the management of AIS. PMID: 25297471 [PubMed - as supplied by publisher]
Source: Neurological Research - December 2, 2014 Category: Neurology Tags: Neurol Res Source Type: research

S100β as a biomarker for differential diagnosis of intracerebral hemorrhage and ischemic stroke.
CONCLUSION: S100β could serve as a potential biomarker for differentiating between ICH and IS and predicting short-term functional outcome after ICH. PMID: 27078704 [PubMed - as supplied by publisher]
Source: Neurological Research - April 16, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Oxidative stress and early mortality in acute ischemic stroke: A prospective cohort study
CONCLUSION: MDA serum level was significantly higher in non-survivors than in survivors patients, so MDA could be used as a predictor for early mortality and short-term outcome of cases with AIS.PMID:37652662 | DOI:10.1080/01616412.2023.2252284
Source: Neurological Research - August 31, 2023 Category: Neurology Authors: Eman A Elhamrawy Heba Shoman Hayam Abdel-Tawab Eshak I Bahbah Rasha Sobhy Elattar Naema R Hussein Marwa Sonbol Asmaa AbdElghany Elsheikh Source Type: research

Evaluating the effect of transplanting umbilical cord matrix stem cells on ischemic tolerance in an animal model of stroke.
CONCLUSION: The pretreatment of the transplanted umbilical cord stem cells in the striatum of ischemic rats possibly leads to restorative events, exerting a decreasing effect on cell death. Subsequently, these events may improve the motor ability and reduce ischemic injuries. PMID: 33167823 [PubMed - as supplied by publisher]
Source: Neurological Research - November 12, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Assessment of rehabilitation following intracerebral hemorrhage in China: findings from the Chinese stroke center alliance
This study showed that the rate of rehabilitation assessment was 74.2%, which is low. Rehabilitation assessment was associated with longer hospital stays and lower mortality. Therefore, patients with acute cerebral haemorrhage should undergo comprehensive and professional rehabilitation assessment.PMID:36126147 | DOI:10.1080/01616412.2022.2123174
Source: Neurological Research - September 20, 2022 Category: Neurology Authors: Jin-Ju Sun Yong-Mei Deng Dan-Dan Wang Hong-Qiu Gu Qi Zhou Yong-Jun Wang Zi-Xiao Li Xing-Quan Zhao Source Type: research

The role of extracranial carotid duplex in predicting functional outcome in first time lacunae strokes
CONCLUSION: In the current study, the most suitable length of stay in hospital for lacunae stroke patients to fully recuperate is ten days. Additionally, CCA EDV might be the key determinant, with baseline diabetes mellitus acting in a medium role, capable of altering long-term outcome functionality and recovery.PMID:36376279 | DOI:10.1080/01616412.2022.2140542
Source: Neurological Research - November 14, 2022 Category: Neurology Authors: Ting-Wei Jiang Ying-Lin Hsu Ju-Lan Yang Yin-Tzer Shih Chih-Ming Lin Source Type: research

The role of Akt (protein kinase B) and protein kinase C in ischemia-reperfusion injury.
Authors: Zhao EY, Efendizade A, Cai L, Ding Y Abstract Stroke is a leading cause of long-term disability and death in the United States. Currently, tissue plasminogen activator (tPA), is the only Food and Drug Administration-approved treatment for acute ischemic stroke. However, the use of tPA is restricted to a small subset of acute stroke patients due to its limited 3-h therapeutic time window. Given the limited therapeutic options at present and the multi-factorial progression of ischemic stroke, emphasis has been placed on the discovery and use of combination therapies aimed at various molecular targets contrib...
Source: Neurological Research - April 21, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Predictive serum biomarkers of patients with cerebral infarction
DISCUSSION: The metabonomics approach may be a useful bioanalytical method for understanding the pathophysiology of cerebral infarction and may provide an experimental basis for the development of clinical biomarkers for stroke.PMID:34763612 | DOI:10.1080/01616412.2021.1987055
Source: Neurological Research - November 12, 2021 Category: Neurology Authors: Yan Kong Yu-Qing Feng Ya-Ting Lu Shi-Sui Feng Zheng Huang Qian-Yi Wang Hui-Min Huang Xue Ling Zhi-Heng Su Yue Guo Source Type: research