• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Quantifying COPD as a risk factor for cardiac disease in a primary prevention cohort
Conclusions In a large real-world population without CVD, people with physician-diagnosed COPD were 25% more likely to have a major CVD event, after adjustment for CVD risk and other factors. This rate is comparable to the rate in people with diabetes and calls for more aggressive CVD primary prevention in the COPD population.
Source: European Respiratory Journal - August 31, 2023 Category: Respiratory Medicine Authors: Maclagan, L. C., Croxford, R., Chu, A., Sin, D. D., Udell, J. A., Lee, D. S., Austin, P. C., Gershon, A. S. Tags: COPD and smoking Original Articles: Tuberculosis and clinical trials Source Type: research

Reply: Association between triple therapy and major adverse cardiovascular events in COPD patients
We thank P. Almagro and P. Martinez-Camblor for their interest in our work and for their salient comments. While we agree that there is no universally accepted definition of major adverse cardiovascular event (MACE), the US Food and Drug Administration (FDA) and the European Medicines Agency include nonfatal myocardial infarction and stroke as well as cardiovascular (CV) mortality in their MACE definition [1]. Importantly, this definition includes both haemorrhagic and ischaemic stroke [1–4]. In our study, we followed this classical "three-point" definition of MACE (including haemorrhagic strokes). While this definit...
Source: European Respiratory Journal - March 2, 2023 Category: Respiratory Medicine Authors: Yang, M.-J., Guo, S.-L., Sin, D. D. Tags: Correspondence Source Type: research

Combination therapy with long-acting bronchodilators and the risk of major adverse cardiovascular events in patients with COPD: a systematic review and meta-analysis
Conclusion Compared with ICS/LABA, dual LAMA/LABA or triple therapy increases cardiovascular risk in patients with COPD. This should be considered in the context of the incremental benefits of these therapies for symptoms and exacerbation rates in patients with COPD, especially in those with a MACE risk of >1% per year.
Source: European Respiratory Journal - February 9, 2023 Category: Respiratory Medicine Authors: Yang, M., Li, Y., Jiang, Y., Guo, S., He, J.-Q., Sin, D. D. Tags: COPD and smoking Original Articles: COPD Source Type: research

Association of obstructive sleep apnoea with cardiovascular events in women and men with acute coronary syndrome
Conclusions In hospitalised ACS patients, OSA was associated with increased risk of subsequent events, particularly among women. Female patients with ACS should not be neglected for OSA screening and dedicated intervention studies focusing on women with ACS and comorbid OSA should be prioritised.
Source: European Respiratory Journal - January 27, 2023 Category: Respiratory Medicine Authors: Wang, X., Fan, J., Guo, R., Hao, W., Gong, W., Yan, Y., Zheng, W., Ai, H., Que, B., Hu, D., Ma, C., Ma, X., Somers, V. K., Nie, S. Tags: Sleep medicine Original Articles: Sleep medicine Source Type: research

Association of COPD exacerbations with cardiovascular events - a population-based cohort study
Conclusion: Severe exacerbations were associated with increased odds of CV events, which in the majority of patients occurred within 30 days after an exacerbation. This highlights that prevention of exacerbations in patients with COPD and concomitant CVD will improve both respiratory and CV health.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Lokke, A., Lange, P., Ibsen, R., Telg, G., Lykkegaard, J., Hilberg, O. Tags: 06.02 - Occupational and environmental health Source Type: research

Prevalence of cardiovascular disease in alpha-1 antrypsin deficiency
We present prevalence of CVD from 1158 patients with AATD who are prospectively followed up as part of the Birmingham AATD registry in the UK. All diagnoses come from either central NHS records or patient reports.The prevalence of CVD was as follows: ischaemic heart disease, 5.2%; heart failure, 0.7%, myocardial infarction, 0.9%; stroke, 1.9%; atrial fibrillation 2.4%. Hypertension and hyperlipidaemia were present in 22% and 10.7% of patients respectively. Factors associated with a higher prevalence of CVD include being male (p <0.001), older age (p <0.001), lower KCO (p = 0.008) and presence of hyperlipidaemia ...
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Bailey, E., Ellis, P., Turner, A., Ellis, P. Tags: 05.02 - Monitoring airway disease Source Type: research

Association between COPD exacerbations and acute cardiovascular events: a systematic literature review
Conclusion: There was an increased risk of acute CV events following a COPD exacerbation. Further research is needed to confirm whether preventing COPD exacerbations also decreases the risk of a subsequent acute CV event.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Müllerova, H., Marshall, J., De Nigris, E., Varghese, P., Pooley, N., Embleton, N., Marjenberg, Z. Tags: Airway pharmacology and treatment Source Type: research

Accelerated FEV1 decline and risk of cardiovascular disease and mortality in a primary care population of COPD patients
Accelerated lung function decline has been associated with increased risk of cardiovascular disease (CVD) in a general population, but little is known about this association in chronic obstructive pulmonary disease (COPD). We investigated the association between accelerated lung function decline and CVD outcomes and mortality in a primary care COPD population. COPD patients without a history of CVD were identified in the Clinical Practice Research Datalink (CPRD)-GOLD primary care dataset (n=36 382). Accelerated decline in forced expiratory volume in 1 s (FEV1) was defined using the fastest quartile of the COPD popula...
Source: European Respiratory Journal - March 4, 2021 Category: Respiratory Medicine Authors: Whittaker, H. R., Bloom, C., Morgan, A., Jarvis, D., Kiddle, S. J., Quint, J. K. Tags: COPD and smoking Original Articles: COPD Source Type: research

Aspirin reduces cardiovascular events in patients with pneumonia: a prior event rate ratio analysis in a large primary care database
This study provides supporting evidence that aspirin use is associated with reduced ischaemic events after pneumonia in a primary care setting. This drug may have a future clinical role in preventing this important complication.
Source: European Respiratory Journal - February 11, 2021 Category: Respiratory Medicine Authors: Hamilton, F., Arnold, D., Henley, W., Payne, R. A. Tags: Original Articles: Pulmonary infection Source Type: research

Smoking status and in-hospital outcomes of ST elevation myocardial infarction patients in a Brazilian public university hospital
Conclusion: Compared to never-smokers and former smokers, current smoking is associated with the occurrence of STEMI at a younger age and with similar in-hospital mortality.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Hofstadler Deiques Fleig, A., Brixner, I., Colissi, N., Boesing, A., Seehaber, A., Fiori, L., Santos, B., Cardoso, A., Anversa, A., Donadel, M., Aita, S., Silva, M., Marques, C., Vaz, J., Schmidt, M., Gottschall, C., Quadros, A., Marques, M., Abelin, A. Tags: Tobacco, smoking control and health educ. Source Type: research

Relation between respiratory diseases and the development of cardiovascular events in patients with respiratory viral infection
Conclusions: COPD does not seem to be an additional risk factor for the development of CVE in patients with respiratory viral infections. However, patients with CVRF and previous CVE more frequently developed new CVE. Patients with CVRF without COPD developed more CVE.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Zambrano Chacon, M. D. L. A., Esteban-Lucia, L., Izquierdo Perez, A., Nieto Roca, L., Venegas Rodriguez, A. M., Garcia Talavera, C. S., Pello Lazaro, A. M., Acena Navaroo, A., Villar Alvarez, F. Tags: Respiratory infections Source Type: research

Effect of obstructive sleep apnoea on cardiovascular outcomes in patients with acute coronary syndrome: a secondary analysis of the RICCADSA trial
Conclusions: OSA is an independent risk factor for MACCE in revascularized patients with ACS.Clinical trial registration: NCT00519597Funding: The Swedish Research Council, ResMed Foundation.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Peker, Y., Thunström, E., Glantz, H., Eulenburg, C. Tags: Sleep and control of breathing Source Type: research

Cardiovascular comorbidity by clinical phenotypes of obstructive sleep apnea and sleeping hours
Conclusion: The ESE group had more severe OSA. Those with ESE and ≤5h/d had more CVC. Those with ≤5h/d had more dyslipidemia, especially when ESE and insomnia were absent.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Torrente Nieto, A., Rojas Calvera, E., Plana Pes, M., Obrador Legares, A., Castella Daga, I., Salvans Sague, M., Marco Segarra, E., Espuna Capote, X., Torres Scianca, D. S., Mota Casals, S., Comas Cufi, M., Ramos Blanes, R., Orriols Martinez, R. Tags: Sleep and control of breathing Source Type: research

Sleep Disordered Breathing association with cardiovascular disease in the French general population
Conclusion: These results confirm that SDB is associated with a higher occurrence of CVD particularly in sleepy and apneic subjects. SDB screening should be relevant to identify people who would benefit from preventive measures.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Balagny, P., Wiernik, E., Matta, J., Frija-Masson, J., Vidal-Petiot, E., Steg, P. G., Ribet, C., Goldberg, M., Zins, M., D'Ortho, M.-P. Tags: Sleep and control of breathing Source Type: research

Benefits of early diagnosis and treatment of obstructive sleep Apnea-Hypopnea syndrome in patients with acute ischemic stroke: SASS (Sleep Apnea in Stroke patients Study)
Conclusions: Acute polygraphy is feasible in patients with AIS. Early treatment of OSAHS could improve stroke outcome, although larger multicentric studies are necessary to confirm these results
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Rodriguez Martin, P. J., Ferrer Galvan, M., Guerrero Zamora, P., Sanchez Gomez, J., Benitez Moya, J. M., Valido Morales, A. S. Tags: Sleep and control of breathing Source Type: research

Pages: 1  2  3  4