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Source: The Lancet Neurology
Condition: Stroke
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Total 244 results found since Jan 2013.
The shared burden of stroke and dementia
Publication date: August 2016 Source:The Lancet Neurology, Volume 15, Issue 9 Author(s): The Lancet Neurology
Source: The Lancet Neurology - July 11, 2016 Category: Neurology Source Type: research
Neurogenic orthostatic hypotension and supine hypertension in Parkinson's disease and related synucleinopathies: prioritisation of treatment targets
Publication date: August 2016 Source:The Lancet Neurology, Volume 15, Issue 9 Author(s): Alberto J Espay, Peter A LeWitt, Robert A Hauser, Aristide Merola, Mario Masellis, Anthony E Lang Neurogenic orthostatic hypotension and supine hypertension are common manifestations of cardiovascular dysautonomia in Parkinson's disease and related synucleinopathies. Because these disorders are haemodynamic opposites, improvement in one might be achieved at the expense of worsening of the other. Thus, management decisions necessitate assessment of the individual risks for patients with coexistent neurogenic orthostatic hypotens...
Source: The Lancet Neurology - July 11, 2016 Category: Neurology Source Type: research
Global burden of stroke and risk factors in 188 countries, during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
Publication date: Available online 9 June 2016 Source:The Lancet Neurology Author(s): Valery L Feigin, Gregory A Roth, Mohsen Naghavi, Priya Parmar, Rita Krishnamurthi, Sumeet Chugh, George A Mensah, Bo Norrving, Ivy Shiue, Marie Ng, Kara Estep, Kelly Cercy, Christopher J L Murray, Mohammad H Forouzanfar Background The contribution of modifiable risk factors to the increasing global and regional burden of stroke is unclear, but knowledge about this contribution is crucial for informing stroke prevention strategies. We used data from the Global Burden of Disease Study 2013 (GBD 2013) to estimate the populati...
Source: The Lancet Neurology - June 9, 2016 Category: Neurology Source Type: research
Stroke is a burdensome but preventable brain disorder
Publication date: Available online 9 June 2016 Source:The Lancet Neurology Author(s): Vladimir Hachinski, Mahmoud Reza Azarpazhooh
Source: The Lancet Neurology - June 9, 2016 Category: Neurology Source Type: research
Alteplase in acute ischaemic stroke: no time to slow down
Publication date: Available online 8 June 2016 Source:The Lancet Neurology Author(s): Stefan Kiechl, Johann Willeit
Source: The Lancet Neurology - June 8, 2016 Category: Neurology Source Type: research
Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis
Publication date: Available online 8 June 2016 Source:The Lancet Neurology Author(s): William N Whiteley, Jonathan Emberson, Kennedy R Lees, Lisa Blackwell, Gregory Albers, Erich Bluhmki, Thomas Brott, Geoff Cohen, Stephen Davis, Geoffrey Donnan, James Grotta, George Howard, Markku Kaste, Masatoshi Koga, Rüdiger von Kummer, Maarten G Lansberg, Richard I Lindley, Patrick Lyden, Jean Marc Olivot, Mark Parsons, Danilo Toni, Kazunori Toyoda, Nils Wahlgren, Joanna Wardlaw, Gregory J del Zoppo, Peter Sandercock, Werner Hacke, Colin Baigent Background Randomised trials have shown that alteplase impr...
Source: The Lancet Neurology - June 8, 2016 Category: Neurology Source Type: research
Dementia risk after spontaneous intracerebral haemorrhage: a prospective cohort study
Publication date: July 2016 Source:The Lancet Neurology, Volume 15, Issue 8 Author(s): Solène Moulin, Julien Labreuche, Stéphanie Bombois, Costanza Rossi, Gregoire Boulouis, Hilde Hénon, Alain Duhamel, Didier Leys, Charlotte Cordonnier Background Dementia occurs in at least 10% of patients within 1 year after stroke. However, the risk of dementia after spontaneous intracerebral haemorrhage that accounts for about 15% of all strokes has not been investigated in prospective studies. We aimed to determine the incidence of dementia and risk factors after an intracerebral haemorrhage. Methods We did a prospective...
Source: The Lancet Neurology - June 6, 2016 Category: Neurology Source Type: research
Dementia after stroke due to intracerebral haemorrhage
Publication date: July 2016 Source:The Lancet Neurology, Volume 15, Issue 8 Author(s): Rustam Al-Shahi Salman, Katie McGoohan, Mark Rodrigues, Martin Dichgans
Source: The Lancet Neurology - June 6, 2016 Category: Neurology Source Type: research
Standardisation of research strategies in acute ischaemic stroke
Publication date: July 2016 Source:The Lancet Neurology, Volume 15, Issue 8 Author(s): Justin F Fraser
Source: The Lancet Neurology - June 6, 2016 Category: Neurology Source Type: research
Early CT Score to establish stroke treatment
Publication date: June 2016 Source:The Lancet Neurology, Volume 15, Issue 7 Author(s): Rüdiger von Kummer
Source: The Lancet Neurology - May 11, 2016 Category: Neurology Source Type: research
Preventing both stroke and dementia
Publication date: June 2016 Source:The Lancet Neurology, Volume 15, Issue 7 Author(s): Vladimir Hachinski, Luciano A Sposato, Moira Kapral
Source: The Lancet Neurology - May 11, 2016 Category: Neurology Source Type: research
Preventing both stroke and dementia – Authors' reply
Publication date: June 2016 Source:The Lancet Neurology, Volume 15, Issue 7 Author(s): Carol Brayne, Yu-Tzu Wu
Source: The Lancet Neurology - May 11, 2016 Category: Neurology Source Type: research
Leonardo's recurrent stroke?
Publication date: June 2016 Source:The Lancet Neurology, Volume 15, Issue 7 Author(s): Coralli Alessia, Perciaccante Antonio
Source: The Lancet Neurology - May 11, 2016 Category: Neurology Source Type: research
Effect of baseline Alberta Stroke Program Early CT Score on safety and efficacy of intra-arterial treatment: a subgroup analysis of a randomised phase 3 trial (MR CLEAN)
We examined the effect of the baseline Alberta Stroke Program Early CT Score (ASPECTS) on the safety and efficacy of intra-arterial treatment in a subgroup analysis of the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands (MR CLEAN). Methods MR CLEAN was a randomised, controlled, open-label, phase 3 trial of intra-arterial treatment in patients (aged ≥18 years from the Netherlands) with proximal arterial occlusion of the anterior circulation, given intra-arterial treatment within 6 h of stroke onset. The primary outcome was 90 day modified Rankin Scale (mRS) sco...
Source: The Lancet Neurology - May 11, 2016 Category: Neurology Source Type: research
Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation
Publication date: Available online 11 May 2016 Source:The Lancet Neurology Author(s): Ángel Chamorro, Ulrich Dirnagl, Xabier Urra, Anna M Planas Treatments for acute ischaemic stroke continue to evolve after the superior value of endovascular thrombectomy was confirmed over systemic thrombolysis. Unfortunately, numerous neuroprotective drugs have failed to show benefit in the treatment of acute ischaemic stroke, making the search for new treatments imperative. Increased awareness of the relevance of rigorous preclinical testing, and appropriate selection of study participants, might overcome the barriers to progress...
Source: The Lancet Neurology - May 11, 2016 Category: Neurology Source Type: research
