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Source: Neuroscience
Condition: Stroke
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Total 160 results found since Jan 2013.
Delayed exercise-induced upregulation of angiogenic proteins and recovery of motor function after photothrombotic stroke in mice
Publication date: Available online 2 March 2021Source: NeuroscienceAuthor(s): Abdullah Al Shoyaib, Faisal F. Alamri, Abbie Biggers, Serob T. Karamyan, Thiruma V. Arumugam, Fakhrul Ahsan, Constantinos M. Mikelis, Taslim A. Al-Hilal, Vardan T. Karamyan
Source: Neuroscience - March 3, 2021 Category: Neuroscience Source Type: research
Receptors, channel proteins, and enzymes involved in microglia-mediated neuroinflammation and treatments by targeting microglia in ischemic stroke
Publication date: Available online 18 February 2021Source: NeuroscienceAuthor(s): Kun Hou, Guichen Li, Jinlu Yu, Kan Xu, Wei Wu
Source: Neuroscience - February 18, 2021 Category: Neuroscience Source Type: research
Phosphofructokinase-1 inhibition promotes neuronal differentiation of neural stem cells and functional recovery after stroke
Publication date: Available online 6 February 2021Source: NeuroscienceAuthor(s): Fengyun Zhang, Qiangming Li, Haiying Liang, Yuxia Zhang
Source: Neuroscience - February 6, 2021 Category: Neuroscience Source Type: research
Matrix Metalloproteinase-9 Expression is Enhanced by Ischemia and Tissue Plasminogen Activator and Induces Hemorrhage, Disability and Mortality in Experimental Stroke
Publication date: Available online 17 January 2021Source: NeuroscienceAuthor(s): Sofiyan Saleem, Dong Wang, Tieqiang Zhao, Ryan D. Sullivan, Guy L. Reed
Source: Neuroscience - January 18, 2021 Category: Neuroscience Source Type: research
Hypoxia Inducible Factor-1α (HIF-1α) Mediates NLRP3 Inflammasome-Dependent-Pyroptotic and Apoptotic Cell Death Following Ischemic Stroke
Publication date: Available online 22 September 2020Source: NeuroscienceAuthor(s): Qian Jiang, Xiaokun Geng, Johnathan Warren, Eric Eugene Paul Cosky, Shawn Kaura, Christopher Stone, Fengwu Li, Yuchuan Ding
Source: Neuroscience - September 23, 2020 Category: Neuroscience Source Type: research
Progressive gray matter atrophy and abnormal structural covariance network in ischemic pontine stroke
Publication date: Available online 3 September 2020Source: NeuroscienceAuthor(s): Ying Wei, Caihong Wang, Jingchun Liu, Peifang Miao, Luobing Wu, Yingying Wang, Kaiyu Wang, Jingliang Cheng
Source: Neuroscience - September 3, 2020 Category: Neuroscience Source Type: research
The mitochondria-targeted peptide, bendavia, attenuated ischemia/reperfusion-induced stroke damage
Publication date: Available online 30 July 2020Source: NeuroscienceAuthor(s): Takahiko Imai, Hirofumi Matsubara, Shinsuke Nakamura, Hideaki Hara, Masamitsu Shimazawa
Source: Neuroscience - July 31, 2020 Category: Neuroscience Source Type: research
Cofilin inhibition by limk1 reduces rod formation and cell apoptosis after ischemic stroke
Publication date: Available online 19 July 2020Source: NeuroscienceAuthor(s): Bin Chen, Wanqing Lin, Wan Qi, Shibin Li, Zhenfeng Hong, Hongjia Zhao
Source: Neuroscience - July 20, 2020 Category: Neuroscience Source Type: research
Stress induced tRNA halves (tiRNAs) as biomarkers for stroke and stroke therapy; Pre-clinical study
Publication date: Available online 19 March 2020Source: NeuroscienceAuthor(s): Kanako Sato, Sherif Rashad, Kuniyasu Niizuma, Teiji Tominaga
Source: Neuroscience - March 19, 2020 Category: Neuroscience Source Type: research
Reduced complexity in stroke with motor deficits: a resting-state fMRI study
Publication date: Available online 17 March 2020Source: NeuroscienceAuthor(s): Liuke Liang, Rongliang Hu, Xuemao Luo, Bao Feng, Wansheng Long, Rong Song
Source: Neuroscience - March 18, 2020 Category: Neuroscience Source Type: research
Blockade of Nogo-A/Nogo-66 receptor 1 (NgR1) Inhibits Autophagic Activation and Prevents Secondary Neuronal Damage in the Thalamus after Focal Cerebral Infarction in Hypertensive Rats
This study aimed to investigate the potential roles of Nogo-A/Nogo-66 receptor 1 (NgR1) in autophagic activation in the ipsilateral thalamus after cerebral infarction. Focal neocortical infarction was established using the middle cerebral artery occlusion (MCAO) method. Secondary damage in the ipsilateral thalamus was assessed by Nissl staining and immunostaining. The expression of Nogo-A, NgR1, Rho-A and Rho-associated coiled-coil containing protein kinase 1 (ROCK1) as well as autophagic flux were evaluated by immunofluorescence and immunoblotting. The roles of Nogo-A–NgR1 signaling in autophagic activation were determi...
Source: Neuroscience - February 22, 2020 Category: Neuroscience Source Type: research
Sleep-restriction inhibits neurogenesis through decreasing the infiltration of CD169+ macrophages to ischemic brain after stroke
In this study, mice were subjected to 60 minutes of cerebral ischemia followed by reperfusion. The SR protocol was accomplished by depriving mice of sleep for 20 hours/day for 14 days starting at 14 days post-ischemia. We found that SR increased CD169+ macrophages infiltration into the ischemic brain parenchyma and inhibited neurogenesis and functional recovery. SR decreased CD169+ macrophages infiltration into the choroid plexus (CP) and cerebrospinal fluid (CSF), accompanied by increased expression of Chemokine C-X3-C-Motif Ligand 1 (CX3CL1) and intercellular adhesion molecule (ICAM-1) via IFN-γ/IFN-γR signaling in the...
Source: Neuroscience - February 19, 2020 Category: Neuroscience Source Type: research
Blockade of Nogo-A/NgR1 inhibits autophagic activation and prevents secondary neuronal damage in the thalamus after focal cerebral infarction in hypertensive rats
This study aimed to investigate the potential roles of Nogo-A/Nogo-66 receptor 1 (NgR1) in autophagic activation in the ipsilateral thalamus after cerebral infarction. Focal neocortical infarction was established using the middle cerebral artery occlusion (MCAO) method. Secondary damage in the ipsilateral thalamus was assessed by Nissl staining and immunostaining. The expression of Nogo-A, NgR1, Rho-A and Rho-associated coiled-coil containing protein kinase 1 (ROCK1) as well as autophagic flux were evaluated by immunofluorescence and immunoblotting. The roles of Nogo-A-NgR1 signaling in autophagic activation were determine...
Source: Neuroscience - February 16, 2020 Category: Neuroscience Source Type: research
Levetiracetam, an antiepileptic drug has neuroprotective effects on intracranial hemorrhage injury
Publication date: Available online 11 February 2020Source: NeuroscienceAuthor(s): Takahiko Imai, Tomoki Sugiyama, Sena Iwata, Shinsuke Nakamura, Masamitsu Shimazawa, Hideaki HaraAbstractIntracranial hemorrhage (ICH) is a devastating disease that induces hematoma formation with poor neuronal outcome. Levetiracetam (LEV) has been approval for epilepsy seizures. In a previous study, LEV exerted protective effects on cerebral ischemia models; however, the detail effects and the influence of LEV on ICH are still unknown. The aim of this study was to investigate whether oral administration of LEV (50 or 150 mg/kg) has protective...
Source: Neuroscience - February 13, 2020 Category: Neuroscience Source Type: research
Exercise plus pharmacological neuromodulation of synaptic inhibition enhance motor function recovery after ischemic stroke
ConclusionsThis study indicated that exercise combined with low-level inhibition of GABAA receptors after stroke could facilitate the recovery of motor function accompanied by BDNF upregulation in the ipsilateral M1. Therefore, this study provides a novel insight of pharmacological neuromodulation into stroke rehabilitation.
Source: Neuroscience - January 25, 2020 Category: Neuroscience Source Type: research
