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Clinical narratives as a predictor for prognosticating functional outcomes after intracerebral hemorrhage
This study aimed to investigate whether clinical narratives can improve the performance for predicting functional outcomes after ICH.
Source: Journal of the Neurological Sciences - September 12, 2023 Category: Neurology Authors: Ling-Chien Hung, Ying-Ying Su, Jui-Ming Sun, Wan-Ting Huang, Sheng-Feng Sung Source Type: research

Mission thrombectomy 2020 (MT2020+) surveys of Caribbean stroke services: A call for action in our region
Stroke is the leading cause of death and adult-onset disability in the Caribbean region. Despite the tremendous advances in acute stroke care in the past 25  years, treatment in the Caribbean lags stroke standards of care. Mission Thrombectomy 2020+ (MT2020+) is a metrics based global campaign focused on increasing access to organized stroke care and mechanical thrombectomy.We conducted two consecutive online surveys across the MT2020+ Caribbean Regio n assessing access to thrombolytics, mechanical thrombectomy and stroke centers.
Source: Journal of the Neurological Sciences - March 31, 2023 Category: Neurology Authors: Gillian Gordon Perue, Ryna Then, Francene Gayle, Siddharth Galav, Yuvateja Thotamalla, Madihah Hepburn, Daidre Rowe, Luis Suazo, Cosme Villam án, Herbert Manosalva, Santiago Ortega-Gutierrez, Dileep Yavagal, Violiza Inoa, On behalf of MT2020+ Caribbean I Source Type: research

Secondhand smoke exposure is independently associated with stroke among non-smoking adults in West Africa
Stroke is a leading cause of disability and mortality worldwide, but little is known about the contribution of secondhand smoke exposure (SHSE) to stroke epidemiology among indigenous Africans.
Source: Journal of the Neurological Sciences - November 8, 2022 Category: Neurology Authors: Akinkunmi Paul Okekunle, Osahon Jeffery Asowata, Adekunle G. Fakunle, Onoja Matthew Akpa, Fred S. Sarfo, Albert Akpalu, Kolawole Wahab, Reginald Obiako, Morenikeji Komolafe, Lukman Owolabi, Godwin O. Osaigbovo, Hemant K. Tiwari, Joshua Akinyemi, Carolyn J Tags: Clinical short communication Source Type: research

Predicting short and long-term mortality after acute ischemic stroke using EHR
In this study, we leveraged administrative data to build predictive models of short- and long-term post-stroke all-cause-mortality.
Source: Journal of the Neurological Sciences - June 28, 2021 Category: Neurology Authors: Vida Abedi, Venkatesh Avula, Seyed-Mostafa Razavi, Bavishi Shreya, Durgesh Chaudhary, Shima Shahjouei, Ming Wang, Christoph J. Griessenauer, Jiang Li, Ramin Zand Source Type: research

Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes due to m.3243A   >  G mutation in a 76-year-old woman
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) with m.3243A  > G mutation is a common type of mitochondrial disease [1,2]. Most patients with MELAS develop stroke-like episodes before the age of 40, a criterion of MELAS [3]. However, increasing reports have demonstrated that elderly subjects (≥ 60 years old) may develop this mitochondrial encephalopathy [4 ,5]. Here, we report a 76-year-old woman who was previously healthy without any organ dysfunction related to mitochondrial abnormalities (except for a mild hearing disability) and developed encephalopathy accompanied by stro...
Source: Journal of the Neurological Sciences - March 18, 2020 Category: Neurology Authors: Kana Ueki, Yoshinobu Wakisaka, Kuniyuki Nakamura, Yuji Shono, Shinichi Wada, Yoji Yoshikawa, Yuta Matsukuma, Takeshi Uchiumi, Dongchong Kang, Takanari Kitazono, Tetsuro Ago Tags: Letter to the Editor Source Type: research

Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes due to m.3243A   >  G mutation in a 76-year-old woman
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) with m.3243A  > G mutation is a common type of mitochondrial disease [1,2]. Most patients with MELAS develop stroke-like episodes before the age of 40, a criterion of MELAS [3]. However, increasing reports have demonstrated that elderly subjects (≥ 60 years old) may develop this mitochondrial encephalopathy [4,5]. Here, we report a 76-year-old woman who was previously healthy without any organ dysfunction related to mitochondrial abnormalities (except for a mild hearing disability) and developed encephalopathy accompanied by st...
Source: Journal of the Neurological Sciences - March 18, 2020 Category: Neurology Authors: Kana Ueki, Yoshinobu Wakisaka, Kuniyuki Nakamura, Yuji Shono, Shinichi Wada, Yoji Yoshikawa, Yuta Matsukuma, Takeshi Uchiumi, Dongchong Kang, Takanari Kitazono, Tetsuro Ago Tags: Letter to the Editor Source Type: research

Deiodinases, organic anion transporter polypeptide polymorphisms and ischemic stroke outcomes
Ischemic stroke is a major cause of premature death and chronic disability worldwide, and individual variation in functional outcome is strongly influenced by genetic factors. Neuroendocrine signaling by the hypothalamic −hypophyseal−thyroid axis is a critical regulator of post-stroke pathogenesis, suggesting that allelic variants in thyroid hormone (TH) signaling can influence stroke outcome.Aim: To examine associations between acute ischemic stroke (AIS) outcome and allelic variants of the TH metabolizing enzy mes deiodinase type 1–3 (DIO1–3) and membrane transporting organic anion polypeptide C1 (OATP1C1).
Source: Journal of the Neurological Sciences - September 10, 2019 Category: Neurology Authors: Saulius Taroza, Daiva Rastenyt ė, Aurelija Podlipskytė, Vaiva Patamsytė, Narseta Mickuvienė Source Type: research

Acute stroke rehabilitation for gait training with cyborg type robot Hybrid Assistive Limb: A pilot study
Robot-assisted gait training following acute stroke could allow patients with severe disability to receive a high dosage and intensity of gait training compared with conventional physical therapy (CP). However, given the limited data on gauging the efficacy of Hybrid Assistive Limb (HAL) on gait training in patients with acute stroke, we aimed to evaluate several outcome measures following gait training with HAL. Patients with first-ever stroke, who required a walking aid and were able to start gait training within 1  week of stroke onset were included in the current study.
Source: Journal of the Neurological Sciences - July 9, 2019 Category: Neurology Authors: Chiaki Yokota, Yukio Yamamoto, Masatoshi Kamada, Michikazu Nakai, Kunihiro Nishimura, Daisuke Ando, Takeo Sato, Masatoshi Koga, Masafumi Ihara, Kazunori Toyoda, Yasuyuki Fujimoto, Hirotaka Odani, Kazuo Minematsu, Takashi Nakajima Source Type: research

The multifactorial etiology of stroke-associated pneumonia
The occurrence of hospital-acquired pneumonia is the most common, feared complication after a stroke that impairs outcomes leading to death and disability(1,2).
Source: Journal of the Neurological Sciences - March 11, 2019 Category: Neurology Authors: Mohamed Al-Khaled Tags: Editorial Source Type: research

Hemoglobin level as a predictor of clinical outcome in patients with ischemic stroke
Guo et al. investigated the association between hemoglobin at acute phase and clinical outcomes in patients with ischemic stroke [1]. The authors selected major disability and death at 3  months as the primary outcomes after stroke onset and events that were separately evaluated as the secondary outcomes. Adjusted odds ratios (ORs) (95% confidence intervals [CIs]) of the highest quartile of hemoglobin against the lowest quartile for the primary outcomes, major disability and death , were 1.38 (1.03–1.86), 1.49 (1.11–1.99), and 0.79 (0.41–1.52), respectively.
Source: Journal of the Neurological Sciences - February 26, 2019 Category: Neurology Authors: Tomoyuki Kawada Tags: Letter to the Editor Source Type: research

Intracerebral hemorrhage outcome: A comprehensive update
Non-traumatic intracerebral hemorrhage (ICH) is associated with a significant global burden of disease, and despite being proportionally less frequent than ischemic stroke, in 2010 it was associated with greater worldwide disability-adjusted life years lost. The focus of outcome assessment after ICH has been mortality in most studies, because of the high early case fatality which reaches 40% in some population-based studies. The most robust and consistent predictors of early mortality include age, severity of neurological impairment, hemorrhage volume and antithrombotic therapy at the time of the event.
Source: Journal of the Neurological Sciences - January 14, 2019 Category: Neurology Authors: Jo ão Pinho, Ana Sofia Costa, José Manuel Araújo, José Manuel Amorim, Carla Ferreira Tags: Review Article Source Type: research

Predictors of long-term survival after spontaneous intracerebral hemorrhage in southern Portugal: A retrospective study of a community representative population
Stroke survivors, particularly of spontaneous intracerebral hemorrhage (SICH), remain at high risk of death on the long-term [1 –3]. A meta-analysis of the long-term prognosis after SICH showed that the 1-year and 5-year mortality rates were 54% and 71% respectively [2]. Along with the post-stroke disability, the presence of underlying risk factors such as hypertension, atherosclerosis, cerebral amyloid angiopathy, diabete s mellitus and the coexistence of several other comorbidities may explain the high rates of mortality on the long-term [3,4].
Source: Journal of the Neurological Sciences - September 17, 2018 Category: Neurology Authors: Hip ólito Nzwalo, Catarina Félix, Jerina Nogueira, Patrícia Guilherme, Fátima Ferreira, Teresa Salero, Sara Ramalhete, Joana Martinez, Maria Mouzinho, Ana Marreiros, Lars Thomassen, Nicola Logallo Tags: Clinical short communication Source Type: research

Neurocognitive outcomes after aneurysmal subarachnoid hemorrhage: Identifying inflammatory biomarkers
Aneurysmal subarachnoid hemorrhage (aSAH) is a severe type of stroke which carries a high case-fatality rate. Those who survive the ictus of aneurysm rupture harbor substantial risks of neurological morbidity, functional disability, and cognitive dysfunction. Although the pervasiveness of cognitive impairment is widely acknowledged as a long-term sequela of aSAH, the mechanisms underlying its development are poorly understood. The onset of aSAH elicits activation of the inflammatory cascade, and ongoing neuroinflammation is suspected to contribute to secondary complications, such as vasospasm and delayed cerebral ischemia.
Source: Journal of the Neurological Sciences - June 25, 2018 Category: Neurology Authors: Eric Watson, Dale Ding, Nicolas K. Khattar, D. Erik Everhart, Robert F. James Tags: Review Article Source Type: research

Potential role of tele-rehabilitation to address barriers to implementation of physical therapy among West African stroke survivors: A cross-sectional survey
The greatest burden from stroke-related disability is borne by Low-and-Middle Income countries (LMICs) where access to rehabilitation after stroke is severely challenged. Tele-rehabilitation could be a viable avenue to address unmet rehabilitation needs in LMICs.
Source: Journal of the Neurological Sciences - September 1, 2017 Category: Neurology Authors: Fred S. Sarfo, Sheila Adamu, Dominic Awuah, Osei Sarfo-Kantanka, Bruce Ovbiagele Source Type: research

Management of post-stroke depression in the Middle East and North Africa: Too little is known
Stroke is among the most common disabilities among adults and most stroke victims live in developing countries. However, little is known about services delivered in these countries for post-stroke depression, a common comorbidity that influences functional outcomes of stroke. In this paper, a physician from Syria reviews the literature on post-stroke depression among patients living in countries of the Middle East and North Africa region in order to examine whether current practices can be improved.
Source: Journal of the Neurological Sciences - May 12, 2017 Category: Neurology Authors: M. Ihsan Kaadan, Mary Jo Larson Tags: Review Article Source Type: research

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