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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Subarachnoid Hemorrhage
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Total 235 results found since Jan 2013.
CXCR2 antagonism attenuates neuroinflammation after subarachnoid hemorrhage
Subarachnoid hemorrhage (SAH) is the deadliest form of a severe cerebrovascular disease, with substantial morbidity and mortality.1 It has been increasingly recognized that SAH induces a series of pathophysiological processes, including neuronal apoptosis,2 neuroinflammatory reactions,3 blood ‒brain barrier disruption,4 and oxidative stress5 are key factors that affect the prognosis of SAH patients. Accumulating evidence has suggested that SAH seriously destroys the extracellular environment of glial cells and immune cells, and then those cells are activated, which produce and release excessive inflammatory cytokines, th...
Source: Journal of Stroke and Cerebrovascular Diseases - July 21, 2023 Category: Neurology Authors: Xiaolin Luo Source Type: research
The clinical utility of dual-energy CT in post-thrombectomy care: Part 1, predictors and outcomes of subarachnoid and intraparenchymal hemorrhage
Dual-energy CT allows differentiation between blood and iodinated contrast. We aimed to determine predictors of subarachnoid and intraparenchymal hemorrhage on dual-energy CT performed immediately post-thrombectomy and the impact of these hemorrhages on 90-day outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2023 Category: Neurology Authors: Seoiyoung Ahn, Nishit Mummareddy, Steven G. Roth, Jacob Jo, Akshay Bhamidipati, Yeji Ko, Julie DiNitto, Rohan V. Chitale, Matthew R. Fusco, Michael T. Froehler Source Type: research
Hospital Discharge and Readmissions Before and During the COVID-19 Pandemic for California Acute Stroke Inpatients
Stroke is a leading cause of death and disability in the United States, with approximately 795,000 new strokes occurring annually, including acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH).1 The Coronavirus Disease 2019 (COVID-19) pandemic has impacted all levels of care for stroke patients, such as delays in initial presentation, reduction in acute therapies, limitations of in-patient resources, delays or lack of initiation of secondary stroke prevention therapy, and limitations in rehabilitation services after hospital discharge.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2023 Category: Neurology Authors: George P. Albert, Daryl C. McHugh, Debra E. Roberts, Adam G. Kelly, Remi Okwechime, Robert G. Holloway, Benjamin P. George Source Type: research
Sex and age effects on risk of non-traumatic subarachnoid hemorrhage: Retrospective cohort study of 124,234 cases using electronic health records
This study describes the antecedent characteristics of SAH patients, compares the risk of SAH between women and men, and explores if this changes with age.
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2023 Category: Neurology Authors: Charlotte H Harrison, Maxime Taquet, Paul J Harrison, Peter J Watkinson, Matthew J Rowland Source Type: research
The effects of aneurysmal subarachnoid hemorrhage on cerebral vessel diameter and flow velocity
Transcranial Doppler flow velocity is used to monitor for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. Generally, blood flow velocities appear inversely related to the square of vessel diameter representing local fluid dynamics. However, studies of flow velocity-diameter relationships are few, and may identify vessels for which diameter changes are better correlated with Doppler velocity. We therefore studied a large retrospective cohort with concurrent transcranial Doppler velocities and angiographic vessel diameters.
Source: Journal of Stroke and Cerebrovascular Diseases - March 16, 2023 Category: Neurology Authors: Richard L. Wang, Kevin J. Gingrich, Awais Vance, Mark D. Johnson, Babu G. Welch, David L. McDonagh Source Type: research
Elevated HMGB1 and sRAGE levels in cerebrospinal fluid of aneurysmal subarachnoid hemorrhage patients
Neuroinflammation after aneurysmal subarachnoid hemorrhage (aSAH) leads to poor outcome of patients. High mobility group box 1 (HMGB1) contributes to inflammation through binding to receptors for advanced glycation end-products (RAGE) in various diseases. We aimed to determine the production of these two factors after aSAH and their relationship with clinical features.
Source: Journal of Stroke and Cerebrovascular Diseases - March 3, 2023 Category: Neurology Authors: Xue-Hong Chu, Hui-Yu Hu, Ivan Steve Godje Godje, Li-Juan Zhu, Jia-Bao Zhu, Yong-Liang Feng, Hai Wang, Yi-Bo Zhang, Juan Huang, Xin-Gang Sun Source Type: research
Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity
Cell-free hemoglobin in the cerebrospinal fluid (CSF-Hb) may be one of the main drivers of secondary brain injury after aneurysmal subarachnoid hemorrhage (aSAH). Haptoglobin scavenging of CSF-Hb has been shown to mitigate cerebrovascular disruption. Using digital subtraction angiography (DSA) and blood oxygenation-level dependent cerebrovascular reactivity imaging (BOLD-CVR) the aim was to assess the acute toxic effect of CSF-Hb on cerebral blood flow and autoregulation, as well as to test the protective effects of haptoglobin.
Source: Journal of Stroke and Cerebrovascular Diseases - January 12, 2023 Category: Neurology Authors: Bart R. Thomson, Henning Richter, Kevin Akeret, Raphael M. Buzzi, Vania Anagnostakou, Christiaan H.B. van Niftrik, Nina Schwendinger, Zsolt Kulcsar, Peter W. Kronen, Luca Regli, Jorn Fierstra, Dominik J. Schaer, Michael Hugelshofer Source Type: research
Modification by an aspiration catheter for vessel stretching in thrombectomy using a stent retriever in vitro
Endovascular mechanical thrombectomy (EVT) using a stent retriever (SR) is the current first-line treatment for acute ischemic stroke (AIS) due to large vessel occlusion with a high revascularization rate, better safety profile, and better clinical outcomes.1 –4 However, the widespread increase in SR use has alerted clinicians about complications after EVT because> 10% of thrombectomy procedures are associated with perioperative complications5 including distal embolization to a new territory (4 –6%), de novo stenosis of the target vessel (3.4%), vessel perforation (0.6–4.9%), vasospasm (3.9–23%), dissection (0.6–...
Source: Journal of Stroke and Cerebrovascular Diseases - January 10, 2023 Category: Neurology Authors: Yasuhiko Nariai, Tomoji Takigawa, Akio Hyodo, Kensuke Suzuki Source Type: research
Characterizing the individual course of health-related quality of life after subarachnoid haemorrhage: Latent growth mixture modelling
Survivors of aneurysmal subarachnoid haemorrhage (SAH) show heterogeneous profiles of health-related quality of life (HrQoL). The aim of this study was to characterize individual differences in the course of HrQoL following SAH using latent growth mixture modelling (LGMM).
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2023 Category: Neurology Authors: Yaroslav Winter, Jens Klotsche, Florian Ringel, Annika Spottke, Thomas Klockgether, Horst Urbach, Bernhard Meyer, Richard Dodel Source Type: research
Characteristics of Subarachnoid Hemorrhage Associated with COVID-19 Infection: A Systematic Review and Descriptive Analysis
Subarachnoid hemorrhage (SAH) has been reported as a neurological manifestation in 0.1% of COVID-19 patients. This systematic review investigated the outcomes and predictive factors of SAH in patients with COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2022 Category: Neurology Authors: Mervyn Jun Rui Lim, Jonathan Yeo, Khi Yung Fong, Sean Wai-Onn Eng, Shuning Fu, Benjamin Yong-Qiang Tan, Leonard Leong Litt Yeo, Vincent Diong Weng Nga, Tseng Tsai Yeo Source Type: research
Risk factors for the rupture of mirror middle cerebral artery aneurysm using computer-assisted semiautomated measurement and hemodynamic analysis
Intracranial aneurysms (IAs) are associated with high rates of death and disability.1,2 Their rupture is accompanied by subarachnoid hemorrhage (SAH) and other severe complications.1,3 Predicting the aneurysms that are prone to rupture is crucial. A study showed that IAs are generated by morphologic changes secondary to blood flow-induced vessel remodeling.4 Hemodynamic and morphological numerically quantified rupture risk.5-7 However, the risks of rupture are also influenced by patient-related factors such as race, gender, hypertension, and smoking.
Source: Journal of Stroke and Cerebrovascular Diseases - November 2, 2022 Category: Neurology Authors: Sheng-Qi Hu, Ru-Dong Chen, Wei-Dong Xu, Jia-Sheng Yu Source Type: research
Use of A Systemic Inflammatory Response Index to Predict Non-Traumatic Non-Aneurysmal Subarachnoid Hemorrhage Patient Outcomes
Patients who suffer from non-traumatic non-aneurysmal subarachnoid hemorrhage (naSAH) episodes still face a risk of clinical complications and poor outcome. As the systemic inflammatory response index (SIRI) has recently been shown to offer value as a tool capable of predicting aneurysmal SAH (aSAH) patient outcomes, this study was designed to gauge SIRI prognostic utility in naSAH patients.
Source: Journal of Stroke and Cerebrovascular Diseases - October 28, 2022 Category: Neurology Authors: Tingting Yu, Zhengyang Wang Source Type: research
Association of asymptomatic cerebral vasospasm with outcomes in survivors of aneurysmal subarachnoid hemorrhage
Cerebral vasospasm (cVSP) is a common complication in aneurysmal subarachnoid hemorrhage (aSAH) and is associated with worse outcomes. However, clinical significance of asymptomatic cVSP is poorly understood. We sought to determine the association of asymptomatic cVSP with functional outcome and hospital length of stay (LOS).
Source: Journal of Stroke and Cerebrovascular Diseases - October 12, 2022 Category: Neurology Authors: Alizeh Shamshad, Elijah M. Persad-Paisley, Linda C. Wendell, Bradford B. Thompson, Michael E. Reznik, Karen L. Furie, Ali Mahta Source Type: research
Elevated blood viscosity is associated with delayed cerebral ischemia in patients with aneurysmal subarachnoid hemorrhage
Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high morbidity and mortality, and delayed cerebral ischemia (DCI) is known as an important contributing factor for poor clinical outcome in patients with aSAH.1,2 Development of DCI is facilitated by cerebral vasospasm with microcirculatory spasms, microthrombi formation, and disruption of cerebral autoregulation.3,4 Therefore, predicting the occurrence of DCI is important for the management of patients with aSAH. Poor initial neurologic status and dense subarachnoid hemorrhage are known factors that increase the incidence of DCI.
Source: Journal of Stroke and Cerebrovascular Diseases - October 3, 2022 Category: Neurology Authors: Ho Jun Yi, Dong-Seong Shin, Bum-Tae Kim Source Type: research
Safety of early rehabilitation in patients with aneurysmal subarachnoid hemorrhage: A retrospective cohort study
To investigate the safety and efficacy of early rehabilitation in patients with aneurysmal subarachnoid hemorrhage (aSAH) patients.
Source: Journal of Stroke and Cerebrovascular Diseases - September 23, 2022 Category: Neurology Authors: Kazuhiro Yokobatake, Tsuyoshi Ohta, Hiroaki Kitaoka, Shingo Nishimura, Kensaku Kashima, Mari Yasuoka, Kohei Nishi, Koji Shigeshima Source Type: research
