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Source: Pediatric Neurology
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Total 229 results found since Jan 2013.
Recurrent stroke-like episodes in -associated early-onset mitochondrial encephalomyopathy
Mutations in the FBXL4 gene have been recently identified as the cause of early-onset mitochondrial encephalomyopathy (EOMEM, OMIM #615471) 1, 2. Progressive supratentorial and cerebellar atrophy are known manifestations (Figure A), stroke-like episodes, although well described in mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), however, have not yet been reported in this entity.
Source: Pediatric Neurology - September 2, 2015 Category: Neurology Authors: Darius Ebrahimi-Fakhari, Angelika Seitz, Stefan Kölker, Georg F. Hoffmann Tags: Visual Diagnosis Source Type: research
Hypertension is Associated with Increased Mortality in Children Hospitalized with Arterial Ischemic Stroke
Recently a single center study suggested that hypertension after stroke in children was a risk factor for mortality. Our goal was to assess the association between hypertension and outcome after arterial ischemic stroke in children from a large national sample.
Source: Pediatric Neurology - December 9, 2015 Category: Neurology Authors: Malik M. Adil, Lauren A. Beslow, Adnan I. Qureshi, Ahmed A. Malik, Lori C. Jordan Tags: Original Articles Source Type: research
Hashimoto encephalopathy presenting with stroke-like episodes in an adolescent female: a case report and literature review
Hashimoto encephalitis (HE) is a rare form of encephalopathy thought to be of autoimmune etiology. Cognitive changes and seizures are the most commonly reported presenting manifestation. Stroke-like episodes have been reported to occur during the disease process as well. To our knowledge we report the first know case of pediatric HE presenting with stroke-like symptoms.
Source: Pediatric Neurology - March 3, 2016 Category: Neurology Authors: Brett R. Graham, Natalie Shiff, Munier Nour, Simona Hasal, Richard Huntsman, Salah Almubarak Tags: Topical Review Source Type: research
Corrigendum to ‘Guidelines for Urgent Management of Stroke in Children’ Pediatric Neurology 56 (2016) 8–17
The Stroke Stat algorithm instituted at Boston Children's Hospital in 2014 was adapted from a pre-existing protocol for acute stroke evaluation and management at the The Hospital for Sick Children and was kindly provided to Dr. Rivkin by Dr. Gabrielle DeVeber in 2008.
Source: Pediatric Neurology - August 31, 2016 Category: Neurology Authors: Michael J. Rivkin, Timothy J. Bernard, Michael M. Dowling, Catherine Amlie-Lefond Tags: Corrigendum Source Type: research
Thrombectomy for acute stroke in childhood: a case report, literature review, and recommendations
AHA/ASA updated guidelines include recommendation for thrombectomy in certain adult stroke cases. The safety and efficacy of thrombectomy in children is unknown.An 8-year-old girl experienced acute stroke symptoms on two occasions while therapeutically anticoagulated on NovalungR. CTs showed proximal vessel thrombi, which were retrieved using a Trevo device without hemorrhagic complications. Post-procedural assessment found respective decreases in the NIHSS score from 10 to 4 and 12 to 7. The indications for treatment and early benefits observed in our case are consistent with other paediatric thrombectomy cases reported.
Source: Pediatric Neurology - September 13, 2016 Category: Neurology Authors: Maria Celeste Buompadre, Kathleen Andres, Lee-Anne Slater, Hadi Mohseni-Bod, Anne-Marie Guerguerian, Helen Branson, Suzanne Laughlin, Derek Armstrong, Mahendranath Moharir, Gabrielle deVeber, Tilman Humpl, Osami Honjo, Shaf Keshavjee, Rebecca Ichord, Vito Tags: Review Article Source Type: research
Endovascular therapy in pediatric stroke: utilization, patient characteristics, and outcomes
Despite strong evidence for endovascular therapy in adults with acute arterial ischemic stroke, limited data exists in children. We aimed to describe endovascular therapy utilization and explore outcomes in a national sample of pediatric arterial ischemic stroke.
Source: Pediatric Neurology - January 24, 2017 Category: Neurology Authors: Jenny L. Wilson, Carl O. Eriksson, Cydni N. Williams Tags: Original Articles Source Type: research
The Potential for Advanced Magnetic Resonance Neuroimaging Techniques in Pediatric Stroke Research
This article was written to provide clinicians and researchers with an overview of a number of advanced neuroimaging techniques in an effort to promote increased utility and the design of future studies using advanced neuroimaging in childhood stroke. The current capabilities of advanced magnetic resonance imaging techniques provide the opportunity to build on our knowledge of the consequences of stroke on the developing brain. These capabilities include providing information about the physiology, metabolism, structure, and function of the brain that are not routinely evaluated in the clinical setting.
Source: Pediatric Neurology - January 23, 2017 Category: Neurology Authors: Trish Domi, Arastoo Vossough, Nicholas V. Stence, Ryan J. Felling, Jackie Leung, Pradeep Krishnan, Christopher G. Watson, P. Ellen Grant, Andrea Kassner Tags: Review Article Source Type: research
Stroke in Ehlers-Danlos Syndrome kyphoscoliotic type (EDSVIA): dissection or vasculitis?
A 13-year-old girl affected with the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS VIA) suffered a stroke of the right middle cerebral artery. MR angiography and arteriography were not indicative of arterial dissection but of cerebral vasculitis. Immunosuppressive treatment resulted in clinical improvement. Six weeks after the stroke she suddenly died from hemorrhagic shock due to spontaneous aortic artery ruptures. Altered collagen function in EDS type VIa may differently affect cerebral and non-cerebral arteries.
Source: Pediatric Neurology - May 29, 2017 Category: Neurology Authors: Annegret Quade, Martin Wiesmann, Joachim Weis, Ingo Kurth, Houman Jalaie, Marianne Rohrbach, Martin H äusler Tags: Short Communication Source Type: research
Transient Ischemic Attack in Pediatric Patients with Moyamoya Disease: Clinical Features, Natural History and Predictors of Stroke
Despite being the most common presentation in pediatric moyamoya patients, TIA in children has rarely been described. The clinical features and risk factors for stroke events of these TIAs remain unclear. The aim of the study is to describe the clinical characteristics of TIA in moyamoya children and explore the risk factors of stroke after TIA.
Source: Pediatric Neurology - July 5, 2017 Category: Neurology Authors: Meng Zhao, Dong Zhang, Shuo Wang, Yan Zhang, Rong Wang, Jizong Zhao Tags: Original Articles Source Type: research
Post Varicella Arterial Ischaemic Stroke in Denmark 2010-2016
Background: Varicella, most often a benign disease of childhood, is associated with an increased risk of arterial ischaemic stroke (AIS) in children. The aim of the present study was to estimate the incidence of post varicella AIS in the Danish child population and describe clinical characteristics of children admitted with post varicella AIS. Methods: In the Danish National Patient Register, we identified inpatients 28 days-16 years of age with a discharge diagnosis of stroke and/or cerebrovascular disease from 2010-2016.
Source: Pediatric Neurology - December 1, 2017 Category: Neurology Authors: Ida Glode Helmuth, K åre Mølbak, Peter Vilhelm Uldall, Anja Poulsen Tags: Original Articles Source Type: research
Pediatric Stroke Imaging
Pediatric stroke is a distinct clinical entity as compared to that in adults due to its unique and diverse set of etiologies. Furthermore, the role and application of diagnostic imaging has specific constraints and considerations. The intention of this article is to review these concepts in a thorough manner to offer a pediatric stroke imaging framework that providers can employ when taking care of these patients.
Source: Pediatric Neurology - July 9, 2018 Category: Neurology Authors: Alexander Khalaf, Michael Iv, Heather Fullerton, Max Wintermark Tags: Review Article Source Type: research
Stroke in pediatric bacterial meningitis: Population-based epidemiology
Bacterial meningitis is a severe infection of the nervous system with a high complication rate including stroke. The purpose of this study is to assess the incidence, risk factors, patterns and outcomes in pediatric meningitis complicated by stroke.
Source: Pediatric Neurology - September 21, 2018 Category: Neurology Authors: Mary Dunbar, Hely Shah, Siddharth Shinde, Joseph Vayalumkal, Otto G. Vanderkooi, Xing-Chang Wei, Adam Kirton Tags: Original Articles Source Type: research
Speech and language impairments after childhood arterial ischemic stroke: does hemisphere matter?
and purpose: The association between left hemisphere stroke and acute speech and language impairment is well documented in adults. However little is known about this association in childhood arterial ischemic stroke (AIS). Here we examined potential predictors of acute speech (dysarthria, apraxia) and language impairments after childhood AIS, including site of lesion.
Source: Pediatric Neurology - November 20, 2018 Category: Neurology Authors: Frederique Liegeois, Cristina Mei, Lauren Pigdon, Katherine J. Lee, Belinda Stojanowski, Mark Mackay, Angela Morgan Tags: Clinical Observations Source Type: research
Protocols and guidelines for stroke in children: Point, counter point
Cerebrovascular diseases carry a heavy burden of disease in children with consequences that last a lifetime1. Perinatal stroke causes most hemiparetic cerebral palsy with additional non-motor consequences affecting diverse aspects of development and quality of life2. Stroke during childhood is also associated with broad neurodevelopmental disabilities and morbidity. Amongst a myriad of potential pathophysiological mechanisms, few are directly treatable and prevention strategies are the exception rather than the rule3,4.
Source: Pediatric Neurology - December 24, 2018 Category: Neurology Authors: Adam Kirton, Michael Dowling Tags: Opinion Paper Source Type: research
What is the role of mechanical thrombectomy in childhood stroke?
Like adults, most children have lifelong morbidity following stroke. Revascularization therapies such as intravenous tissue plasminogen activator and mechanical thrombectomy may be options to decrease this morbidity in selected children, although currently there are no evidence-based recommendations to guide treatment. The utility and safety of mechanical thrombectomy in childhood stroke is unknown due to that lack of safety trials, case-controlled trials, and comprehensive retrospective studies.
Source: Pediatric Neurology - January 16, 2019 Category: Neurology Authors: Megan Barry, Danial Hallam, Timothy J. Bernard, Catherine Amlie-Lefond Tags: Topical Review Source Type: research
