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Source: Pediatric Neurology

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Total 229 results found since Jan 2013.

A Case of Successful Manual Aspiration Thrombectomy in a Pediatric Patient
Timely recognition of pediatric stroke at major medical centers is improving and while treatment guidelines for pediatric stroke exist, no extensive study establishing the efficacy of surgical or thrombolytic treatment has been completed. Extrapolation of adult guidelines to pediatric patients remains the mainstay of treatment without adequate information available regarding safety and efficacy in children. Recent trials have demonstrated revascularization and clinical improvement following endovascular retrieval therapy in adults with acute large vessel occlusive stroke.
Source: Pediatric Neurology - March 21, 2016 Category: Neurology Authors: Gregory M. Weiner, Rafey A. Feroze, Nitin Agarwal, David M. Pancykowski, William J. Ares, Ali Kooshkabadi, Dana D. Cummings, Vincent Carson, Amin Aghaebrahim, Brian T. Jankowitz Tags: Topical Review Source Type: research

Successful Manual Aspiration Thrombectomy in a Pediatric Patient
Timely recognition of stroke at major pediatric medical centers is improving, and although treatment guidelines for pediatric stroke exist, no extensive study establishing the efficacy of surgical or thrombolytic treatment has been completed. Extrapolation of adult guidelines to pediatric patients remains the mainstay of treatment in the absence of adequate information regarding safety and efficacy in children. Recent trials have demonstrated revascularization and clinical improvement after endovascular retrieval therapy in adults with acute large vessel occlusive stroke.
Source: Pediatric Neurology - March 21, 2016 Category: Neurology Authors: Gregory M. Weiner, Rafey A. Feroze, BSE, Nitin Agarwal, David M. Pancykowski, William J. Ares, Ali Kooshkabadi, Dana D. Cummings, Vincent Carson, Amin Aghaebrahim, Brian T. Jankowitz Tags: Topical Review Source Type: research

Vascular imaging outcomes of childhood primary angiitis of the central nervous system
Inflammation affecting cerebral blood vessels is a common cause of stroke in children. Arterial abnormalities on vascular imaging are an important risk factor for stroke recurrence. We aimed to describe the vascular imaging outcomes in children with primary angiitis of the central nervous system (cPACNS) after 12-months, and identify factors associated with vascular progression and stroke recurrence.
Source: Pediatric Neurology - June 16, 2016 Category: Neurology Authors: Jorina Elbers, Derek Armstrong, Ivanna Yau, Susanne Benseler Source Type: research

Successful Manual Aspiration Thrombectomy in  a Pediatric Patient
Timely recognition of stroke at major pediatric medical centers is improving, and although treatment guidelines for pediatric stroke exist, no extensive study establishing the efficacy of surgical or thrombolytic treatment has been completed. Extrapolation of adult guidelines to pediatric patients remains the mainstay of treatment in the absence of adequate information regarding safety and efficacy in children. Recent trials have demonstrated revascularization and clinical improvement after endovascular retrieval therapy in adults with acute large vessel occlusive stroke.
Source: Pediatric Neurology - March 21, 2016 Category: Neurology Authors: Gregory M. Weiner, Rafey A. Feroze, BSE, Nitin Agarwal, David M. Pancykowski, William J. Ares, Ali Kooshkabadi, Dana D. Cummings, Vincent Carson, Amin Aghaebrahim, Brian T. Jankowitz Tags: Topical Review Source Type: research

Vascular Imaging Outcomes of Childhood Primary Angiitis of the Central Nervous System
Inflammation affecting cerebral blood vessels is a common cause of stroke in children. Arterial abnormalities on vascular imaging are an important risk factor for stroke recurrence. We aimed to describe the vascular imaging outcomes in children with primary angiitis of the central nervous system after 12 months and identify factors associated with vascular progression and stroke recurrence.
Source: Pediatric Neurology - June 16, 2016 Category: Neurology Authors: Jorina Elbers, Derek Armstrong, Ivanna Yau, Susanne Benseler Tags: Original Article Source Type: research

Successful Manual Aspiration Thrombectomy in  a Pediatric Patient
Timely recognition of stroke at major pediatric medical centers is improving, and although treatment guidelines for pediatric stroke exist, no extensive study establishing the efficacy of surgical or thrombolytic treatment has been completed. Extrapolation of adult guidelines to pediatric patients remains the mainstay of treatment in the absence of adequate information regarding safety and efficacy in children. Recent trials have demonstrated revascularization and clinical improvement after endovascular retrieval therapy in adults with acute large vessel occlusive stroke.
Source: Pediatric Neurology - March 21, 2016 Category: Neurology Authors: Gregory M. Weiner, Rafey A. Feroze, BSE, Nitin Agarwal, David M. Pancykowski, William J. Ares, Ali Kooshkabadi, Dana D. Cummings, Vincent Carson, Amin Aghaebrahim, Brian T. Jankowitz Tags: Topical Review Source Type: research

Increased Prevalence Of Stroke Recurrence And Stroke Related Mortality In Children With Sickle Cell Disease In Nigeria: Evidence For A Secondary Stroke Prevention Trial.
To improve the quality of care for children with sickle cell anemia (SCA) in Kano, Nigeria, we initiated a standard care protocol in 2014 to manage children with strokes at Aminu Kano Teaching Hospital.
Source: Pediatric Neurology - January 16, 2019 Category: Neurology Authors: Shehu U. Abdullahi, Michael R. DeBaun, Lori C. Jordan, Najibah A. Galadanci Tags: Original Articles Source Type: research

Acute and delayed cerebrovascular injury from gunshot to the head in a 12-year-old child during the COVID-19 pandemic
We present a child shot during the pandemic who had significant acute and delayed cerebrovascular injury, but no stroke, likely due to medical mangement.
Source: Pediatric Neurology - February 10, 2022 Category: Neurology Authors: Meredith R. Golomb, Juan G. Tejada, Katrina A. Ducis, Mesha L. Martinez Tags: Short Communication Source Type: research

Response to Passos et al
We appreciate the letter from Drs. Passos, Nzwalo, and colleagues as well as their interest in our article, “Hemorrhagic and Ischemic Stroke in Children with Cancer.” They report important data on the long term rate of stroke and cerebrovascular disease in adult survivors of childhood primary central nervous system tumors followed in their neuro-oncology clinic at Centro Hospitalar do Algarve in Lisbon, Portugal. We applaud their efforts to carefully follow their patients longitudinally and assess for nonovert lesions such as microbleeds, cavernous malformations, superficial siderosis, and moyamoya. Such careful follow...
Source: Pediatric Neurology - December 5, 2013 Category: Neurology Authors: Corina Noje, Kenneth Cohen, Lori Jordan Tags: Letters to the Editor Source Type: research

Post-Varicella Angiopathy: A Series of 4 Patients With Focus on Virologic and Neuroimaging Findings
Conclusions: Systematic search for virologic markers in cerebrospinal fluid will contribute to the understanding of the pathogenesis of idiopathic childhood stroke and can be considered as a prerequisite for the development of clear diagnostic criteria and relevant treatment strategies for post-varicella angiopathy. The role of antiviral and immunosuppressive medication needs to be clarified.
Source: Pediatric Neurology - January 16, 2014 Category: Neurology Authors: Ulrike Dunkhase-Heinl, Brian Stausbøl-Grøn, Johnny Christensen, John R. Ostergaard Tags: Original Articles Source Type: research

Advances and Future Directions for Tuberous Sclerosis Complex Research: Recommendations from the 2015 Strategic Planning Conference
On March 10-12, 2015, the National Institute of Neurological Disorders and Stroke and the Tuberous Sclerosis Alliance sponsored a workshop in Bethesda, Maryland to assess progress and new opportunities for research in tuberous sclerosis complex with the goal of updating the 2003 Research Plan for Tuberous Sclerosis (http://www.ninds.nih.gov/about_ninds/plans/tscler_research_plan.htm). In addition to the National Institute of Neurological Disorders and Stroke and Tuberous Sclerosis Alliance, participants in the strategic planning effort and workshop included representatives from six other Institutes of the National Institut...
Source: Pediatric Neurology - April 1, 2016 Category: Neurology Authors: Mustafa Sahin, Elizabeth P. Henske, Brendan D. Manning, Kevin C. Ess, John J. Bissler, Eric Klann, David J. Kwiatkowski, Steven L. Roberds, Alcino Silva, Coryse St. Hillaire-Clarke, Lisa R. Young, Mark Zervas, Laura A. Mamounas, Tuberous Sclerosis Complex Tags: Topical Review Source Type: research

Quality of Life in Pediatric Moyamoya Disease
Moyamoya Disease (MMD) is a progressive intracranial arteriopathy with high risk of stroke. Its impact on quality of life is unstudied. We surveyed children with MMD and compared their quality of life to chronically-ill children and children with stroke to better understand the impact of this diagnosis.
Source: Pediatric Neurology - June 26, 2016 Category: Neurology Authors: Alexander Ball, Gary Steinberg, Jorina Elbers Source Type: research

Advances and Future Directions for Tuberous Sclerosis Complex Research: Recommendations From the 2015 Strategic Planning Conference
On March 10 to March 12, 2015, the National Institute of Neurological Disorders and Stroke and the Tuberous Sclerosis Alliance sponsored a workshop in Bethesda, Maryland, to assess progress and new opportunities for research in tuberous sclerosis complex with the goal of updating the 2003 Research Plan for Tuberous Sclerosis (http://www.ninds.nih.gov/about_ninds/plans/tscler_research_plan.htm). In addition to the National Institute of Neurological Disorders and Stroke and Tuberous Sclerosis Alliance, participants in the strategic planning effort and workshop included representatives from six other Institutes of the Nationa...
Source: Pediatric Neurology - April 1, 2016 Category: Neurology Authors: Mustafa Sahin, Elizabeth P. Henske, Brendan D. Manning, Kevin C. Ess, John J. Bissler, Eric Klann, David J. Kwiatkowski, Steven L. Roberds, Alcino J. Silva, Coryse St. Hillaire-Clarke, Lisa R. Young, Mark Zervas, Laura A. Mamounas, Tuberous Sclerosis Comp Tags: Topical Review Source Type: research

Large Vessel Vasculopathy in Children with Sickle Cell Disease: an MRI study of Infarct Topography and Focal Atrophy
Large-vessel vasculopathy (LVV) increases stroke risk in pediatric sickle cell disease (SCD) beyond the baseline elevated stroke risk in this vulnerable population. The mechanisms underlying this added risk and its unique impact on the developing brain are not established.
Source: Pediatric Neurology - December 6, 2016 Category: Neurology Authors: Kristin P. Guilliams, Melanie E. Fields, Dustin K. Ragan, Yasheng Chen, Cihat Eldeniz, Monica L. Hulbert, Michael M. Binkley, James N. Rhodes, Joshua S. Shimony, Robert C. McKinstry, Katie Vo, Hongyu An, Jin-Moo Lee, Andria L. Ford Tags: Original Articles Source Type: research