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Source: Heart Rhythm
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Total 406 results found since Jan 2013.
Cryoballoon pulmonary vein ablation and left atrial appendage closure combined procedure: A long-term follow-up analysis
The combined left atrial appendage closure (LAAC) and cryoenergy pulmonary vein isolation (PVI) procedure has been proven safe and effective in managing stroke in patients with nonvalvular atrial fibrillation (AF), although most data refer to procedures performed using radiofrequency as the main energy source.
Source: Heart Rhythm - March 26, 2019 Category: Cardiology Authors: Gaetano Fassini, Alessio Gasperetti, Gianpiero Italiano, Stefania Riva, Massimo Moltrasio, Antonio Dello Russo, Michela Casella, Anna Maltagliati, Fabrizio Tundo, Benedetta Majocchi, Luca Arioli, Ghaliah Al-Mohani, Gianluca Pontone, Mauro Pepi, Claudio To Source Type: research
To the Editor — Patients with atrial fibrillation with hypertrophic cardiomyopathy: Do we need new stroke risk stratification?
Because of high thromboembolic risk, lifelong oral anticoagulation is recommended in all patients with nonvalvular atrial fibrillation (NVAF) with hypertrophic cardiomyopathy (HCM).1 –3 We read with great interest the article by Tsuda et al,4 who rightly emphasized the importance of HCM in thromboembolism in patients with AF.
Source: Heart Rhythm - April 3, 2019 Category: Cardiology Authors: Boyoung Joung, Gregory Y.H. Lip Tags: Letter to the Editor Source Type: research
EP News: Clinical
Packer et al (JAMA March 15, 2019;https://doi.org/10.1001/jama.2019.0693; Epub ahead of print, PMID 30874766) evaluated whether catheter ablation is more effective than conventional medical therapy for improving outcomes in atrial fibrillation (AF). A total of 2204 symptomatic patients with AF 65 years and older or younger than 65 years with 1 or more risk factors for stroke were enrolled. The catheter ablation group (n = 1108) underwent pulmonary vein isolation. The drug therapy group (n = 1096) received standard rhythm and/or rate control drugs.
Source: Heart Rhythm - May 24, 2019 Category: Cardiology Authors: N.A. Mark Estes Tags: EP News Source Type: research
Thromboembolic, Bleeding, and Mortality Risks among Patients with Nonvalvular Atrial Fibrillation Treated with Dual Antiplatelet Therapy versus Oral Anticoagulants: A Population-Based Study
Dual antiplatelet therapy (DAPT) with aspirin plus clopidogrel is used for stroke prevention in patients with atrial fibrillation (AF) when patients refuse to use oral anticoagulants (OAC) in clinical practice. However, there are limited clinical data comparing these treatments.
Source: Heart Rhythm - July 31, 2019 Category: Cardiology Authors: Wallis C.Y. Lau, Ian J. Douglas, Ian C.K. Wong, Liam Smeeth, Gregory Y.H. Lip, Wai K. Leung, Chung-Wah Siu, Bernard M.Y. Cheung, Michael T.C. Mok, Esther W. Chan Source Type: research
EP News: Allied Professionals
Di Biase et al (J Am Coll Cardiol 2019;74:1019, PMID 31439209) sought to assess the incidence of thromboembolic (TE) events such as stroke and transient ischemic attack (TIA) in patients with atrial fibrillation (AF) undergoing ablation for AF that included left atrial appendage (LAA) isolation (LAAI). The st udy group comprised all patients who underwent LAAI as part of their ablation strategy and who were without AF 6 months after ablation. All patients were continued on oral anticoagulation (OAC) with either warfarin or direct oral anticoagulant (DOAC) for the first 6 months.
Source: Heart Rhythm - September 15, 2019 Category: Cardiology Authors: Erica S. Zado Tags: EP News Source Type: research
Incidence and Causes of In-hospital Outcomes and 30-day Readmissions After Percutaneous Left Atrial Appendage Closure: A United States Nationwide Retrospective Cohort Study Using Claims Data
Percutaneous left atrial appendage closure (p-LAAC) emerged as an option for stroke prevention in atrial fibrillation (AF) patients ’ ineligible for long-term anticoagulation.Real-world data on its in-hospital and 30-day readmission measures are limited.
Source: Heart Rhythm - September 16, 2019 Category: Cardiology Authors: Venkat L.K. Vuddanda, Mohit K. Turagam, Nikita A. Umale, Zubair Shah, Dhanunjaya R. Lakkireddy, Krzysztof Bartus, Finnian R. McCausland, Poonam Velagapudi, Moussa Mansour, E. Kevin Heist Source Type: research
Pacing in vasovagal syncope: a physiological paradox?
CThe physiological principles underlying pacemaker treatment in patients with vasovagal syncope (VVS) have never been reviewed. Current knowledge suggests that pacing the right heart is unlikely to correct blood pressure (BP) during a vasovagal reaction. In adults, the reason for this is that stroke volume (SV) is dictated by central blood volume (CBV) contained in the cardiopulmonary vessels within the chest (i.e. left ventricular preload). Preceding posture-triggered VVS, there is a significant fall in CBV and therefore in SV and cardiac output (CO) long before the onset of bradycardia.
Source: Heart Rhythm - September 23, 2019 Category: Cardiology Authors: Jelle SY. de Jong, David L. Jardine, Jacques WM. Lenders, Wouter Wieling Source Type: research
EP News: Clinical
Yasada et al (N Engl J Med 2019;381:1103, PMID 31475793) conducted a prospective randomized multicenter trial of 2236 patients with atrial fibrillation (AF) who had undergone percutaneous coronary intervention or coronary artery bypass grafting more than 1 year earlier or who had angiographically confirmed coronary artery disease not requiring revascularization. Patients were randomized to monotherapy with rivaroxaban or combination therapy with rivaroxaban plus a single antiplatelet agent. The primary efficacy end point was a composite of stroke, systemic embolism, myocardial infarction, unstable ang ina requiring revas...
Source: Heart Rhythm - October 27, 2019 Category: Cardiology Authors: N.A. Mark Estes Tags: EP News Source Type: research
Pacing in vasovagal syncope: physiology, pacemaker sensors and recent clinical trials. Precise patient selection and measurable benefit.
The role of pacing in vasovagal syncope (VVS) is considered from a physiological basis. Most VVS patients lose consciousness due to hypotension before severe bradycardia/asystole occurs. Patients that benefit from dual-chamber pacing are typically older with highly symptomatic, late-onset, frequent and severe syncope with short/no prodrome and documented severe cardioinhibition. Tilt-testing is of value in patients with recurrent unexplained syncope to identify important hypotensive susceptibility stemming from reduced venous return and stroke volume.
Source: Heart Rhythm - February 5, 2020 Category: Cardiology Authors: Richard Sutton, Jelle SY. de Jong, Julian M. Stewart, Artur Fedorowski, Frederik J. de Lange Source Type: research
EP News: Allied Professionals
Using data from implantable loop recorders (ILRs) inserted in patients with risk factors for stroke but without history of atrial fibrillation (AF), Diederichsen et al (Circulation 2020; DOI 10.1161/CIRCULATIONAHA.119.044407; PMID 32114796) used simulation techniques to assess how often various rhythm monitors would pick up episodes of AF during regular screening. The patients were part of the LOOP trial (Atrial Fibrillation Detected by Continuous ECG Monitor ing; ClinicalTrials.gov Identifier: NCT02036450).
Source: Heart Rhythm - March 20, 2020 Category: Cardiology Authors: Erica S. Zado Tags: EP News Source Type: research
HRS white paper on atrial fibrillation centers of excellence: Rationale, considerations, and goals
Atrial fibrillation (AF) remains an important global problem.1 –3 AF continues to lead to poor health outcomes, including reduced quality of life (QoL) and increased risks of heart failure, cognitive impairment, stroke, and death.4,5 Moreover, it has a significant financial impact on health care systems and their associated economies.6–8 In order to improve care for patients with AF, there is an increasing recognition that current care must evolve. Health care organizations should move from a system of siloed outpatient and inpatient clinicians and health care facilities to a system of integrated, coordinated, and pati...
Source: Heart Rhythm - May 4, 2020 Category: Cardiology Authors: Jonathan P. Piccini, James Allred, T. Jared Bunch, Thomas F. Deering, Luigi Di Biase, Ayman A. Hussein, William R. Lewis, Suneet Mittal, Andrea Natale, Jose Osorio, Douglas L. Packer, Christian Ruff, Andrea M. Russo, Prashanthan Sanders, Amber Seiler, Dav Source Type: research
EP News Clinical July 1, 2020
Osmancik and colleagues (J Am Coll Cardiol. 2020; 75:3122-3135. PMID: 32586585) compared left atrial appendage closure (LAAC) with direct oral anticoagulants in a multicenter, randomized, noninferiority trial. A high-risk patient cohort (CHA2DS2-VASc: 4.7 ± 1.5) was randomized to receive LAAC (n = 201) or DOAC (n = 201). At 19.9 months of follow-up, the annual rates of the primary outcome were 10.99% with LAAC and 13.42% with DOAC (HR: 0.84; p = 0.44; p = 0.004 for noninferiority). There were no differences between groups for the components of the c omposite endpoint: all-stroke/TIA (HR: 1.00), clinically significant blee...
Source: Heart Rhythm - July 3, 2020 Category: Cardiology Authors: N. A. Mark Estes Source Type: research
Rationale, considerations, and goals for atrial fibrillation centers of excellence: A Heart Rhythm Society perspective
Atrial fibrillation (AF) remains an important global problem.1 –3 AF continues to lead to poor health outcomes, including reduced quality of life (QoL) and increased risks of heart failure, cognitive impairment, stroke, and death.4,5 Moreover, it has a significant financial impact on health care systems and their associated economies.6–8 In order to improve care for patients with AF, there is an increasing recognition that current care must evolve. Health care organizations should move from a system of siloed outpatient and inpatient clinicians and health care facilities to a system of integrated, coordinated, and pati...
Source: Heart Rhythm - May 4, 2020 Category: Cardiology Authors: Jonathan P. Piccini, James Allred, T. Jared Bunch, Thomas F. Deering, Luigi Di Biase, Ayman A. Hussein, William R. Lewis, Suneet Mittal, Andrea Natale, Jose Osorio, Douglas L. Packer, Christian Ruff, Andrea M. Russo, Prashanthan Sanders, Amber Seiler, Dav Source Type: research
