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Source: Heart Rhythm

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Total 406 results found since Jan 2013.

Pericardial Effusion Requiring Intervention in Patients Undergoing Percutaneous Left Atrial Appendage Occlusion: Prevalence, Predictors and Associated In-hospital Adverse Events from 17,700 Procedures in the United States
Left atrial appendage occlusion has shown promise in mitigating risk of stroke in selected patients with atrial fibrillation.
Source: Heart Rhythm - May 17, 2021 Category: Cardiology Authors: Muhammad Bilal Munir, Muhammad Zia Khan, Douglas Darden, Deepak Kumar Pasupula, Sudarshan Balla, Frederick T. Han, Ryan Reeves, Jonathan C. Hsu Source Type: research

Clinical phenotypes of patients with atrial fibrillation enrolled in randomized controlled trials:AFFIRM and EAST-AFNET 4
Yang et al. conducted a retrospective study of the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) trial.1 Their findings did not support the first primary Early Treatment of Atrial Fibrillation for Stroke Prevention Trial (EAST-AFNET 4) outcome.2 Clinical phenotypes of atrial fibrillation (AF) should be considered.
Source: Heart Rhythm - May 20, 2021 Category: Cardiology Authors: Norman C. Wang Source Type: research

EP News: Allied Professionals
In this multicenter, randomized trial (Whitlock et al. New Engl J Med. 2021;384:2081-91. PMID: 33999547), the investigators sought do determine whether surgical left atrial appendage occlusion (LAAO) prevents ischemic stroke in patients with atrial fibrillation (AF). Patients with AF and CHA2DS2-VASc score of at least 2 who were scheduled to undergo cardiac surgery were randomized on a 1:1 basis to surgical LAAO or no occlusion. The surgeon and surgical team were informed of the randomization, but teams taking care of the patient post-operatively including during long term follow-up, and who were charged with managing anti...
Source: Heart Rhythm - June 9, 2021 Category: Cardiology Authors: Erica S. Zado Source Type: research

Letter to the Editor — Clinical Phenotypes in AF Trials
Yang et  al1 conducted a retrospective study of the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) trial. Their findings did not support the first primary Early Treatment of Atrial Fibrillation for Stroke Prevention Trial (EAST-AFNET 4) outcome.2 Clinical phenotypes of atrial fib rillation (AF) should be considered.
Source: Heart Rhythm - May 20, 2021 Category: Cardiology Authors: Norman C. Wang Tags: Letters to the Editor Source Type: research

Long-term outcomes and periprocedural safety and efficacy of percutaneous left atrial appendage closure in a UK tertiary centre: 11-year experience
Left atrial appendage occlusion (LAAO) has been widely adopted as a strategy for stroke prevention in patients with atrial fibrillation ineligible for oral anticoagulation.
Source: Heart Rhythm - June 11, 2021 Category: Cardiology Authors: Andre Briosa e Gala, Michael TB. Pope, Cristiana Monteiro, Milena Leo, Sam Dawkins, James D. Newton, Timothy R. Betts Source Type: research

The combination of coronary sinus ostial atresia/abnormalities and a small persistent left superior vena cava —Opportunity for left ventricular lead implantation and unrecognized source of thromboembolic stroke
Coronary sinus (CS) ostial atresia/abnormalities prevent access to the CS from the right atrium (RA) for left ventricular (LV) lead implantation. Some patients with CS ostial abnormalities also have a small persistent left superior vena cava (sPLSVC).
Source: Heart Rhythm - May 7, 2021 Category: Cardiology Authors: Fengwei Zou, Seth J. Worley, Torkel Steen, Matthew McKillop, Santosh Padala, Susan O ’Donoghue, Basar Candemir, Khalil Kanjwal, Michael Kaufman, Sahar Mouram, Matthew Sellers, David Strouse, Athanasios Thomaides, Devi Nair, Cyrus A. Hadadi, Alexander Ku Tags: Clinical Source Type: research

Early recurrence of atrial tachyarrhythmia post-atrial fibrillation ablation: Filling in the blank
Supported by the recent results of the Catheter Ablation vs Antiarrhythmic Drug Therapy for Atrial Fibrillation (CABANA) and Early Treatment of Atrial Fibrillation for Stroke Prevention (EAST-AFNET4) trials, catheter ablation is a preferable contemporary linchpin in the treatment of symptomatic atrial fibrillation (AF).1,2 Traditionally, the efficacy with ablation has been broadly defined by either objective arrhythmic recurrence such as atrial arrhythmias of over 30 seconds in duration or subjective recurrence of symptomatic arrhythmias.
Source: Heart Rhythm - June 29, 2021 Category: Cardiology Authors: Christopher A. Groh, T. Jared Bunch Source Type: research

Early recurrence of atrial tachyarrhythmia post –atrial fibrillation ablation: Filling in the blank
Supported by the recent results of the Catheter Ablation vs Antiarrhythmic Drug Therapy for Atrial Fibrillation (CABANA) and Early Treatment of Atrial Fibrillation for Stroke Prevention (EAST-AFNET4) trials, catheter ablation is a preferable contemporary linchpin in the treatment of symptomatic atrial fibrillation (AF).1,2 Traditionally, the efficacy with ablation has been broadly defined by either objective arrhythmic recurrence such as atrial arrhythmias of over 30 seconds in duration or subjective recurrence of symptomatic arrhythmias.
Source: Heart Rhythm - June 29, 2021 Category: Cardiology Authors: Christopher A. Groh, T. Jared Bunch Tags: Editorial Commentary Source Type: research

B-po05-209 pericardial effusion after left atrial appendage occlusion resulting from an aortic dissection
Atrial fibrillation (AF) affects 2.3 million Americans. In those unfit for long-term anticoagulation, left atrial appendage occlusion (LAAO) is an alternative for stroke prophylaxis.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Kara Stout, Andrew Goldsweig Source Type: research

B-po05-197 increased use of direct-acting oral anticoagulants and anticoagulation rates in a large health care system
Oral anticoagulation (OAC) has been underused in patients with atrial fibrillation (AF) at risk for stroke. Data from registries has shown OAC rates in eligible patients of 50-60%. The use of direct oral anticoagulants (DOACs) has improved OAC rates but contemporary data are lacking.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: John V. Wylie, Michael V. Orlov Source Type: research

B-po05-154 an updated meta-analysis comparing left atrial appendage closure and oral anticoagulation
Left atrial appendage closure (LAAC) trials such as PREVAIL and PROTECT revealed non-inferiority of LAAC compared to warfarin. The recently published PRAGUE study showed that LAAC was non-inferior to direct oral anti-coagulants. Current guidelines give a IIb recommendation for LAAC in patients with non-valvular atrial fibrillation (NVAF) with increased risk of stroke and contraindication to long-term anticoagulation.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Sisir Siddamsetti, Arshad Muhammad Iqbal, Alexander Shinn, Sandeep Gautam Source Type: research

B-po05-153 quarterly versus annual ecg screening for atrial fibrillation in older chinese
Screening for atrial fibrillation before symptoms manifested and subsequent initiation of oral anticoagulants (OACs), could prevent stroke and death. The most cost-effective strategy to screen atrial fibrillation in high-risk population aged 65 and over remains unknown.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Wei Zhang, Yi Chen, Ji-Guang Wang Source Type: research

B-po05-145 contemporary clinical and economic outcomes among oral anticoagulant treated and untreated elderly patients with atrial fibrillation
Oral anticoagulants (OACs) are the standard of care for decreasing stroke risk in atrial fibrillation (AF) patients.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Muhammad Bilal Munir, Patrick Hlavacek, Allison Keshishian Jennifer Guo, Rajesh Mallampati Mauricio Ferri, Cristina Russ Birol Emir, Matthew Cato, Huseyin Yuce, Jonathan C. Hsu Source Type: research

B-po05-139 changes in flow dynamics due to persistent atrial fibrillation in a chronically paced canine model
Atrial Fibrillation (AF) increases the risk of stroke, presumably because poor left atrial (LA) contraction leads to impaired blood flow and the potential for clots to form. Previous studies have not looked at flow changes over the course of AF progression.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Eugene Kwan, Jiawei Dong, Saranyu Thanasitsomboon, Orvelin Roman Elliott Hurd, Lucas Timmins Jason Mendes, Edward DiBella, Robert MacLeod, Derek J. Dosdall, Ravi Ranjan Source Type: research

B-po05-086 structural and tissue remodeling of the left atrium and left atrial appendage after atrial fibrillation ablation
Large left atrium appendage (LAA) orifice area and an increased left atrium (LA) volume have been associated with an increased risk of ischemic stroke. Catheter ablation (CA) of atrial fibrillation (AF) leads to anatomical and tissue changes within the LA and LAA.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Yichi Zhang, Lilas Dagher, Abdel Hadi El Hajjar, Aneesh Dhore, Alan Morris, Eugene Kholmovski, Chao Huang, Raman Danrad, Tarek Ayoub, Nassir Marrouche Source Type: research