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Source: Heart Rhythm
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Total 406 results found since Jan 2013.
MicroRNAs emerging as mediators of remodeling with atrial fibrillation
Atrial fibrillation (AF) is the most common cardiac arrhythmia and is now established as an independent risk factor for stroke. Moreover, a concomitant diagnosis of AF greatly complicates treatment for a number of disease processes such as diabetes and congestive heart failure. Given the recognized additional burden that AF places on the health-care system, significant research has been performed in an attempt to delineate mechanisms that contribute to AF initiation as well as progression. Understandably, there is an extensive body of research that has identified abnormalities in ionic channels/electrogenic processes that ...
Source: Heart Rhythm - March 25, 2013 Category: Cardiology Authors: Adam W. Akerman, Rupak Mukherjee Tags: Editorial Commentary Source Type: research
Platelet-derived growth factor: A promising therapeutic target for atrial fibrillation
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and is characterized by substantial electrophysiological and structural changes. AF is associated with an increased risk of stroke, heart failure, and overall mortality. The risk of developing AF increases with age and with other risk factors such as diabetes and underlying heart disease. Currently, the therapeutic options for the treatment of AF have moderate effectiveness, and side effects, including proarrhythmic events, can often be encountered. The limited effectiveness of antiarrhythmic drugs available for the management of AF is especially proble...
Source: Heart Rhythm - April 8, 2013 Category: Cardiology Authors: Céline Fiset Tags: Editorial Commentary Source Type: research
Long-term ECG monitoring using an implantable loop recorder for the detection of atrial fibrillation after cavotricuspid isthmus ablation in patients with atrial flutter
Conclusions: Our data show that many (but not all) patients develop new AF within the first 4 months of flutter ablation. Since external ECG monitoring for this duration is impractical, the ILR has an important role for long-term AF surveillance. Future research should be directed toward identifying the relationship between duration/burden of AF and stroke and improving existing ILR technology.
Source: Heart Rhythm - August 1, 2013 Category: Cardiology Authors: Suneet Mittal, Evgeny Pokushalov, Alexander Romanov, Martha Ferrara, Aysha Arshad, Dan Musat, Mark Preminger, Tina Sichrovsky, Jonathan S. Steinberg Tags: Atrial Fibrillation Source Type: research
The funny and not-so-funny effects of dronedarone
Atrial fibrillation (AF) is the most common supraventricular tachycardia, affecting over 2 million patients, and is associated with 100,000 new strokes per year. Data from large, long-term epidemiologic studies such as the Framingham Heart Study show a strong link between AF, stroke, congestive heart failure, and mortality. In addition, the expected rise in the elderly population in Western countries will cause an increase in the clinical burden of AF. Historically, AF has been treated by pharmacological rate and/or rhythm control in combination with chronic oral anticoagulation medication to reduce the risk of embolic phe...
Source: Heart Rhythm - August 26, 2013 Category: Cardiology Authors: David S. Park, Gregory E. Morley Tags: Editorial Commentary Source Type: research
Phased RF ablation in persistent atrial fibrillation
Background: Persistent and long-standing persistent atrial fibrillation (AF) often requires extensive and/or repeat radiofrequency (RF) ablation procedures.Objective: The Tailored Treatment of Persistent Atrial Fibrillation (TTOP-AF) study assessed the effectiveness and safety of the phased RF system in a randomized controlled comparison of medical therapy against phased RF ablation for the management of persistent and long-standing persistent AF.Methods: Patients who had failed at least 1 antiarrhythmic drug (AAD) were randomized (2:1) to ablation management (AM) or medical management (MM). AM patients were allowed up to ...
Source: Heart Rhythm - November 18, 2013 Category: Cardiology Authors: John Hummel, Gregory Michaud, Robert Hoyt, David DeLurgio, Abdi Rasekh, Fred Kusumoto, Michael Giudici, Dan Dan, David Tschopp, Hugh Calkins, Lucas Boersma, TTOP-AF Investigators Tags: Ablation Source Type: research
Endocardial occlusion of incompletely surgically ligated left atrial appendage using an Amplatzer septal occluder device
A 55-year-old man underwent a surgical Maze procedure for the treatment of nonvalvular atrial fibrillation with concomitant surgical suture ligation of left atrial appendage (LAA). Baseline transesophageal echocardiography (TEE) and computed tomography (CT) angiography revealed a normal LAA free of thrombus (A). Ten days after surgery, he developed an acute embolic stroke. Repeat TEE and CT angiography demonstrated an incompletely surgically ligated LAA (ISLL) without thrombus, with the ISLL neck dimensions measuring 3 × 3 mm (B). He was promptly initiated on oral anticoagulation (OAC) therapy. But owing to intolerance to...
Source: Heart Rhythm - June 24, 2013 Category: Cardiology Authors: Arash Aryana, Sean Bailey, Padraig Gearoid O’Neill, André d’Avila Tags: Image Source Type: research
Multidetector computed tomography may be an adequate screening test to reduce periprocedural stroke in atrial fibrillation ablation: A multicenter propensity-matched analysis
Source: Heart Rhythm - January 27, 2014 Category: Cardiology Authors: Sung-Jin Hong, Jong-Yun Kim, Jin-Bae Kim, Jung-Hoon Sung, Dong Wook Kim, Jae-Sun Uhm, Hye-Jeong Lee, Young Jin Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung Source Type: research
Renin-angiotensin System Gene Polymorphisms Predict the Risk of Stroke in Patients with Atrial Fibrillation- A 10-year Prospective Follow-up Study
Source: Heart Rhythm - April 11, 2014 Category: Cardiology Authors: Chia-Ti Tsai, Sheng-Nan Chang, Shu-Hsuan Chang, Jen-Kuang Lee, Lian-Yu Lin, Cho-Kai Wu, Chih-Chieh Yu, Yi-Chih Wang, Chuen-Den Tseng, Ling-Ping Lai, Juey-Jen Hwang, Fu-Tien Chiang, Jiunn-Lee Lin Source Type: research
Multidetector computed tomography may be an adequate screening test to reduce periprocedural stroke in atrial fibrillation ablation: A multicenter propensity-matched analysis
Source: Heart Rhythm - January 27, 2014 Category: Cardiology Authors: Sung-Jin Hong, Jong-Yun Kim, Jin-Bae Kim, Jung-Hoon Sung, Dong Wook Kim, Jae-Sun Uhm, Hye-Jeong Lee, Young Jin Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung Source Type: research
Risk of Stroke and Intracranial Hemorrhage in 9,727 Chinese with Atrial Fibrillation in Hong Kong
Source: Heart Rhythm - April 15, 2014 Category: Cardiology Authors: Chung-Wah Siu, Gregory Y H Lip, PhD. Kwok-Fai Lam, Hung-Fat Tse Source Type: research
Risk of stroke and intracranial hemorrhage in 9727 Chinese with atrial fibrillation in Hong Kong
Source: Heart Rhythm - April 15, 2014 Category: Cardiology Authors: Chung-Wah Siu, Gregory Y.H. Lip, Kwok-Fai Lam, Hung-Fat Tse Source Type: research
Renin–angiotensin system gene polymorphisms predict the risk of stroke in patients with atrial fibrillation: A 10-year prospective follow-up study
Source: Heart Rhythm - April 11, 2014 Category: Cardiology Authors: Chia-Ti Tsai, Sheng-Nan Chang, Shu-Hsuan Chang, Jen-Kuang Lee, Lian-Yu Lin, Cho-Kai Wu, Chih-Chieh Yu, Yi-Chih Wang, Chuen-Den Tseng, Ling-Ping Lai, Juey-Jen Hwang, Fu-Tien Chiang, Jiunn-Lee Lin Source Type: research
Incidence and Prediction of Ischemic Stroke among Atrial Fibrillation Patients with End-Stage Renal Disease Requiring Dialysis
Source: Heart Rhythm - June 18, 2014 Category: Cardiology Authors: Tze-Fan Chao, Chia-Jen Liu, Kang-Ling Wang, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Fa-Po Chung, Jo-Nan Liao, Tzeng-Ji Chen, Gregory Y.H. Lip, Shih-Ann Chen Source Type: research
Risk Predictors of Stroke and Mortality Following Ablation For Atrial Fibrillation: the California experience 2005-2009
Source: Heart Rhythm - July 15, 2014 Category: Cardiology Authors: Uma N. Srivatsa, Beate Danielsen, Ivan Anderson, Ezra Amsterdam, Nayereh Pezeshkian, Yingbo Yang, Richard H. White Source Type: research
Risk of New-Onset Atrial Fibrillation and Stroke after Radiofrequency Ablation of Isolated Typical Atrial Flutter
Source: Heart Rhythm - July 1, 2014 Category: Cardiology Authors: Jessica Voight, Mehmet Akkaya, Porur Somasundaram, Rehan Karim, Salimah Valliani, Younghoon Kwon, Selcuk Adabag Source Type: research
