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Source: Heart Rhythm

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Total 406 results found since Jan 2013.

Botulinum Toxin Injection in the Autonomic Ganglion Plexi to Prevent Post-operative Atrial Fibrillation: More than a Cosmetic Treatment
Postoperative atrial fibrillation (POAF) frequently complicates cardiac surgery, and is associated with prolonged hospitalization, increased risk of development of AF during follow-up, stroke and mortality. Several comorbidities predispose to POAF, among which inflammation and oxidative stress, but also structural atrial remodeling is associated with an increased POAF risk(1). One potential pathway that caught attention recently is the autonomic dysbalance during cardiac surgery in relation to the occurrence of POAF.
Source: Heart Rhythm - September 18, 2018 Category: Cardiology Authors: Joris R. de Groot Source Type: research

Anticoagulation in elderly patients with nonvalvular atrial fibrillation: A balancing act
Atrial fibrillation (AF) is a major global health burden because of its rising prevalence and associated complications such as stroke and mortality.1 In the 2010 Global Burden of Disease study, approximately 33 million people were estimated to have AF, but this number is projected to increase exponentially due to the ageing population1
Source: Heart Rhythm - September 18, 2018 Category: Cardiology Authors: Ameenathul Fawzy, Gregory Y.H. Lip Tags: Editorial Commentary Source Type: research

Botulinum toxin injection in the autonomic ganglion plexi to prevent postoperative atrial fibrillation: More than a cosmetic treatment
Postoperative atrial fibrillation (POAF) frequently complicates cardiac surgery and is associated with prolonged hospitalization, increased risk of development of atrial fibrillation (AF) during follow-up, stroke, and mortality. Several comorbidities predispose to POAF, including inflammation and oxidative stress but also structural atrial remodeling, are associated with an increased risk of POAF.1 One potential pathway that received attention recently is autonomic dysbalance during cardiac surgery in relation to the occurrence of POAF.
Source: Heart Rhythm - September 18, 2018 Category: Cardiology Authors: Joris R. de Groot Tags: Editorial Commentary Source Type: research

Impact of dense ‘Smoke’ detected on Transesophageal Echocardiography on stroke-risk in patients with atrial fibrillation undergoing catheter ablation
Spontaneous echocardiographic contrast ( ‘Smoke’) within the left atrial cavity on transesophageal echocardiography (TEE) suggests low blood flow velocities in the heart that may consequently lead to thromboembolic (TE) events.
Source: Heart Rhythm - October 9, 2018 Category: Cardiology Authors: Ömer Gedikli, Sanghamitra Mohanty, Chintan Trivedi, Carola Gianni, Qiong Chen, Domenico Giovanni Della Rocca, J. David Burkhardt, Javier E. Sanchez, Patrick Hranitzky, G. Joseph Gallinghouse, Amin Al-Ahmad, Rodney Horton, Luigi Di Biase, Andrea Natale Source Type: research

Impact of dense “smoke” detected on transesophageal echocardiography on stroke risk in patients with atrial fibrillation undergoing catheter ablation
Spontaneous echocardiographic contrast ( ”smoke”) within the left atrial cavity on transesophageal echocardiography (TEE) suggests low blood flow velocities in the heart that may lead to thromboembolic (TE) events.
Source: Heart Rhythm - October 9, 2018 Category: Cardiology Authors: Ömer Gedikli, Sanghamitra Mohanty, Chintan Trivedi, Carola Gianni, Qiong Chen, Domenico Giovanni Della Rocca, J. David Burkhardt, Javier E. Sanchez, Patrick Hranitzky, G. Joseph Gallinghouse, Amin Al-Ahmad, Rodney Horton, Luigi Di Biase, Andrea Natale Source Type: research

Harmonized Outcome Measures for Use in Atrial Fibrillation Patient Registries and Clinical Practice
Atrial fibrillation (AF) affects an estimated 33 million people worldwide, leading to increased mortality and an increased risk of heart failure and stroke. Many AF patient registries exist, but the ability to link and compare data across registries is hindered by differences in the outcome measures collected by each registry and a lack of harmonization.
Source: Heart Rhythm - November 15, 2018 Category: Cardiology Authors: Hugh Calkins, Richard E. Gliklich, Michelle B. Leavy, Jonathan P. Piccini, Jonathan C. Hsu, Sanghamitra Mohanty, William Lewis, Saman Nazarian, Mintu P. Turakhia Source Type: research

EP News: Clinical
Sindet-Pedersen et  al (J Am Coll Cardiol 2018;72:1790, PMID 30286922) investigated the risk of bleeding, ischemic stroke, myocardial infarction (MI), and all-cause mortality associated with direct oral anticoagulants (DOACs) compared with vitamin K antagonists (VKAs) in combination with aspirin, clopidogrel, or both in patients with atrial fibrillation (AF) after MI and/or percutaneous coronary intervention (PCI). Overall, 3222 patients were included in the retrospective registry analysis; 875 (27%) were treated with VKA+single antiplatelet therapy (SAPT), 595 (18%) were treated with DOAC+SAPT, 1074 (33%) were treated wi...
Source: Heart Rhythm - November 23, 2018 Category: Cardiology Authors: N.A. Mark Estes Tags: EP News Source Type: research

Electrical isolation of the left atrial appendage increases the risk of ischemic stroke and transient ischemic attack regardless of postisolation flow velocity
Electrical isolation of the left atrial appendage (LAA) is associated with a lower rate of atrial fibrillation (AF) recurrence in patients undergoing radiofrequency catheter ablation. However, LAA isolation can significantly impair LAA contractility.
Source: Heart Rhythm - November 28, 2018 Category: Cardiology Authors: Yun Gi Kim, Jaemin Shim, Suk-Kyu Oh, Kwang-No Lee, Jong-Il Choi, Young-Hoon Kim Tags: Featured Article Source Type: research

Left Atrial Appendage Closure Device Implantation in Patients with Prior Intracranial Hemorrhage
The Watchman ™ device (Boston Scientific, MN), used for left atrial appendage closure (LAAC) was approved for stroke prevention in patients with atrial fibrillation (AF) and an appropriate rationale to avoid long-term oral anticoagulation. Patients with AF and prior intracranial hemorrhage (ICH) were excluded from clinical trials due to perceived risks of peri-operative anticoagulation.
Source: Heart Rhythm - December 2, 2018 Category: Cardiology Authors: Erika Hutt, Oussama M. Wazni, Walid I. Saliba, Mohamed Kanj, Khaldoun G. Tarakji, Jose Aguilera, Amr F. Barakat, Peter Rasmussen, Ken Uchino, Andrew Russman, Shazam Hussain, Dolora Wisco, Samir Kapadia, Bruce D. Lindsay, Ayman A. Hussein Source Type: research

Atrial Fibrillation Occurring During Head-up Tilt Test: Once detected, AF should be monitored, regardless of how it is detected
Atrial fibrillation (AF) often progresses to more sustained forms and raises the risk of ischemic stroke or sinus node dysfunction (SND). However, there has been no data on the clinical outcomes of AF developed during head-up tilt testing (HUT).
Source: Heart Rhythm - December 4, 2018 Category: Cardiology Authors: Jun Hyung Kim, Sung Ho Lee, Seung-Jung Park, Kyoung Min Park, Young Keun On, June Soo Kim Source Type: research

CHA2DS2-VASc scores and Intermountain Mortality Risk Scores for the joint risk stratification of dementia among patients with atrial fibrillation
High CHA2DS2-VASc scores in atrial fibrillation (AF) patients are generally associated with increased risks of stroke and dementia. At lower CHA2DS2-VASc scores, there remains an unquantifiable cranial injury risk, necessitating an improved risk assessment method within these lower-risk groups.
Source: Heart Rhythm - January 1, 2019 Category: Cardiology Authors: Kevin G. Graves, Heidi T. May, Victoria Jacobs, Kirk U. Knowlton, Joseph B. Muhlestein, Donald L. Lappe, Jeffrey L. Anderson, Benjamin D. Horne, T. Jared Bunch Tags: Featured Article Source Type: research

Left Atrial Appendage Closure Device Implantation in Patients with Atrial Fibrillation and Prior Intracranial Hemorrhage “No Man Left Behind”
Several LAA closure devices have been developed for patients with atrial fibrillation (AF) seeking an alternative to long-term oral anticoagulation (OAC). The PROTECT AF trial was the first multicenter randomized controlled trial (RCT) comparing LAA closure device vs. OAC with Warfarin. Primary safety events were statistically more frequent in the device group (7.4% vs. 4.4%). At a mean follow up of 3.8 years LAA closure device showed superiority for the primary efficacy endpoint (i.e., composite of stroke, cardiovascular death and systemic embolism), with a 34% relative risk reduction in total mortality1-3 However, with t...
Source: Heart Rhythm - January 14, 2019 Category: Cardiology Authors: Luigi Di Biase, Jorge Romero Source Type: research

Atrial fibrillation occurring during head-up tilt testing: Once detected, atrial fibrillation should be monitored, regardless of how it is detected
Atrial fibrillation (AF) often progresses to more sustained forms and increases the risk of ischemic stroke or sinus node dysfunction. However, there have been no data on the clinical outcomes of patients who developed AF during head-up tilt testing (HUT).
Source: Heart Rhythm - December 4, 2018 Category: Cardiology Authors: Jun Hyung Kim, Sung Ho Lee, Seung-Jung Park, Kyoung Min Park, Young Keun On, June Soo Kim Source Type: research

Cryoballoon Pulmonary Vein Ablation and Left Atrial Appendage Closure Combined Procedure: a long term follow up analysis Cryoablation with Concomitant Left Atrial Appendage Closure
combined left atrial appendage closure (LAAC) and cryo-energy pulmonary vein isolation (PVI) procedure has been proven safe and effective in managing stroke in patients with non-valvular atrial fibrillation (AF), although most data refer to procedures performed using radiofrequency (RF) as main energy source.
Source: Heart Rhythm - March 26, 2019 Category: Cardiology Authors: Gaetano Fassini, Alessio Gasperetti, Gianpiero Italiano, Stefania Riva, Massimo Moltrasio, Antonio Dello Russo, Michela Casella, Anna Maltagliati, Fabrizio Tundo, Benedetta Majocchi, Luca Arioli, Ghaliah Al-Mohani, Gianluca Pontone, Mauro Pepi, Claudio To Source Type: research

Atrial fibrillation patients with hypertrophic cardiomyopathy: Do we need new stroke risk stratification?
Due to very high thromboembolic risk, life-long oral anticoagulation is recommended in all hypertrophic cardiomyopathy (HCM) patients with non-valvular atrial fibrillation (NVAF).1-3 We read with great interest the paper by Tsuda et al.4 who rightly emphasized the importance of HCM on thromboembolism in patients with AF.
Source: Heart Rhythm - April 3, 2019 Category: Cardiology Authors: Boyoung Joung, Gregory Y.H. Lip Source Type: research