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Source: Diabetes and Metabolism

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Total 66 results found since Jan 2013.

Do SGLT2 inhibitors and GLP-1 receptor agonists modulate differently the risk of stroke ? Discordance between randomised controlled trials and observational studies
Diabetes Metab. 2023 Sep 5:101474. doi: 10.1016/j.diabet.2023.101474. Online ahead of print.ABSTRACTStroke represents a major burden in patients with type 2 diabetes, yet this cerebrovascular complication has been less carefully investigated than the risk of cardiovascular mortality, heart failure and renal disease. Some data suggested that glucagon peptide-1 receptor agonists (GLP-1RAs) exert a better protection against stroke than sodium-glucose cotransporter 2 inhibitors (SGLT2is). However, this conclusion was derived from indirect comparisons in absence of any head-to-head randomised controlled trial (RCT). The present...
Source: Diabetes and Metabolism - September 7, 2023 Category: Endocrinology Authors: Andr é J Scheen Source Type: research

Associations of MAFLD and MAFLD subtypes with the risk of the incident myocardial infarction and stroke
In conclusion, a diagnosis of MAFLD is associated with an increased risk of MI or stroke, and the assessment of MAFLD and its subtypes should be a component of the cardiovascular risk assessment.PMID:37586479 | DOI:10.1016/j.diabet.2023.101468
Source: Diabetes and Metabolism - August 16, 2023 Category: Endocrinology Authors: Shen Chen Hongliang Xue Rong Huang Ke Chen Haoyang Zhang Xu Chen Source Type: research

Type 2 diabetes and cardiorenal syndromes. A nationwide French hospital cohort study
CONCLUSION: . Patients with T2DM represent almost half of patients with CRS and are younger than their non-diabetic counterparts. T2DM doubles the risk of CRS and increases the risk of death, cardiovascular outcome, and end-stage kidney disease but not ischemic stroke after CRS.PMID:36931430 | DOI:10.1016/j.diabet.2023.101441
Source: Diabetes and Metabolism - March 17, 2023 Category: Endocrinology Authors: Valentin Maisons Jean-Michel Halimi Gr égoire Fauchier Jean-Baptiste de Fr éminville Nicolas Goin Juliette Gueguen Philippe Gatault B énédicte Sautenet Denis Angoulvant Julien Herbert Arnaud Bisson Pierre-Henri Ducluzeau Laurent Fauchier Source Type: research