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Source: Diabetes and Metabolism

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Total 66 results found since Jan 2013.

Heart failure hospitalisation relative to major atherosclerotic events in type 2 diabetes with versus without chronic kidney disease: a meta-analysis of cardiovascular outcomes trials
CONCLUSION: CKD is associated with a shift in the profile of cardiovascular events in people with type 2 diabetes, marked by a disproportionate increase in HHF relative to MACE.PMID:33744399 | DOI:10.1016/j.diabet.2021.101249
Source: Diabetes and Metabolism - March 21, 2021 Category: Endocrinology Authors: Julian W Sacre Dianna J Magliano Jonathan E Shaw Source Type: research

Elevated triglyceride-glucose index predicts risk of incident ischaemic stroke: The Rural Chinese Cohort Study
CONCLUSION: Elevated TyG index is an independent predictor of ischaemic stroke in the general population, and insulin resistance may be positively associated with future stroke risk.PMID:33722769 | DOI:10.1016/j.diabet.2021.101246
Source: Diabetes and Metabolism - March 16, 2021 Category: Endocrinology Authors: Yang Zhao Haohang Sun Weidong Zhang Yuanlin Xi Xuezhong Shi Yongli Yang Lu Jie Ming Zhang Liang Sun Hu Dongsheng Source Type: research

Impact of gender on relative rates of cardiovascular events in patients with diabetes.
CONCLUSION: Although men have higher absolute risks of cardiovascular complications, the relative risks of cardiovascular complications associated with diabetes are higher in women than in men. PMID: 33454437 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - January 14, 2021 Category: Endocrinology Authors: Angoulvant D, Ducluzeau PH, Renoult-Pierre P, Fauchier G, Herbert J, Semaan C, Bodin A, Bisson A, Fauchier L Tags: Diabetes Metab Source Type: research

SGLT2i as fourth-line therapy and risk of mortality, end-stage renal diseases and cardiovascular diseases in patients with type 2 diabetes mellitus.
CONCLUSION: Among T2DM patients initiating fourth-line therapy, SGLT2i users had significant benefits in lowering risk of CVD, and potential benefits in lowering risks of ESRD and all-cause mortality. SGLT2i was the preferred fourth-line glucose-lowering medication least likely to be associated with complication risks. PMID: 33039672 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - October 8, 2020 Category: Endocrinology Authors: Wong CKH, Tang EHM, Man KKC, Chan EWY, Wong ICK, Lam CLK Tags: Diabetes Metab Source Type: research

Screening for non-alcoholic fatty liver disease using liver stiffness measurement and its association with chronic kidney disease and cardiovascular complications in patients with type 2 diabetes.
CONCLUSION: - These results suggest that NAFLD and significant LF (as assessed by FibroScan) are very commonly seen in T2DM outpatients with no known liver disease attending a secondary-care diabetes service, and that increased LF is associated with a greater proportion of chronic vascular complications, especially CKD. PMID: 31786361 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - November 27, 2019 Category: Endocrinology Authors: Mantovani A, Turino T, Lando MG, Gjini K, Byrne CD, Zusi C, Ravaioli F, Colecchia A, Maffeis C, Salvagno G, Lippi G, Bonora E, Targher G Tags: Diabetes Metab Source Type: research

Association between difference in blood pressure reduction and risk of cardiovascular events in a type 2 diabetes population: a meta-regression analysis.
CONCLUSION: A reduction in BP lowers the risk of stroke, but does not appear to affect the risk of other cardiovascular events in a T2D population. PMID: 31150802 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - May 27, 2019 Category: Endocrinology Authors: Grenet G, Le HH, Bejan-Angoulvant T, Erpeldinger S, Boussageon R, Kassaï B, Moulin P, Gueyffier F, Cucherat M Tags: Diabetes Metab Source Type: research

Association of C-peptide with diabetic vascular complications in type 2 diabetes.
CONCLUSION: -: C-peptide was positively associated with CVD, but inversely associated with DR progression. The association between C-peptide and CVD could be due to associated metabolic risk factors. PMID: 31026551 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - April 22, 2019 Category: Endocrinology Authors: Wang Y, Wan H, Chen Y, Xia F, Zhang W, Wang C, Fang S, Zhang K, Li Q, Wang N, Lu Y Tags: Diabetes Metab Source Type: research

Limited benefit of haemoglobin glycation index as risk factor for cardiovascular disease in type 2 diabetes patients.
CONCLUSION: Similar to HbA1c, higher HGI is related to higher risk of cardiovascular events in patients with T2DM without CVD. As HbA1c has proved to be a comparable risk factor, and obtaining and interpreting the HGI is complicated, any additional benefit of applying the HGI in clinical settings is likely to be limited. PMID: 29784563 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - May 8, 2018 Category: Endocrinology Authors: Østergaard HB, Mandrup-Poulsen T, Berkelmans GFN, van der Graaf Y, Visseren FLJ, Westerink J, SMART Study Group Tags: Diabetes Metab Source Type: research

Actinic keratosis and diabetes complications: A nationwide population-based study in South Korea (2009-2015).
CONCLUSION: This study has revealed that the incidence of AK is higher in diabetes patients with ocular, renal and cardiovascular complications. PMID: 29249611 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - November 29, 2017 Category: Endocrinology Authors: Bok Lee Y, Hyun Lee J, Young Choi J, Soo Yu D, Do Han K, Gyu Park Y Tags: Diabetes Metab Source Type: research

Impact of glucose-lowering therapies on risk of stroke in type 2 diabetes.
Abstract Patients with type 2 diabetes (T2D) have an increased risk of stroke compared with people without diabetes. However, the effects of glucose-lowering drugs on risk of ischaemic stroke in T2D have been less extensively investigated than in coronary heart disease. Some evidence, including the UKPDS, has suggested a reduced risk of stroke with metformin, although the number of studies is limited. Inhibition of the KATP channels increases ischaemic brain lesions in animals. This is in agreement with a recent meta-analysis showing an increased risk of stroke with sulphonylureas vs. various comparators as both m...
Source: Diabetes and Metabolism - May 15, 2017 Category: Endocrinology Authors: Bonnet F, Scheen AJ Tags: Diabetes Metab Source Type: research