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Source: The American Journal of Cardiology
Condition: Ischemic Stroke
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Total 182 results found since Jan 2013.
Incidence and Outcome of High On-Treatment Platelet Reactivity in Patients With Non-ST Elevation Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention (from the VIP VerifyNow and Inhibition of Platelet Reactivity Study)
In conclusion, 1/3 of patients with acute coronary syndromes who underwent percutaneous coronary intervention and stenting showed high on-treatment RPR on bedside monitoring. They had a worse prognosis, but the level of platelet inhibition was not independently associated with the incidence of ischemic or bleeding events.
Source: The American Journal of Cardiology - June 7, 2013 Category: Cardiology Authors: Francesco Saia, Massimiliano Marino, Gianluca Campo, Marco Valgimigli, Paolo Guastaroba, Nevio Taglieri, Stefano Tondi, Antonio Manari, Vincenzo Guiducci, Pietro Sangiorgio, Elisabetta Varani, Paolo Magnavacchi, Rossana De Palma, Antonio Marzocchi Tags: Coronary Artery Disease Source Type: research
A Meta-Analysis of Mortality and Major Adverse Cardiovascular and Cerebrovascular Events Following Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement for Severe Aortic Stenosis
The purpose of this meta-analysis was to compare postprocedural mortality and major adverse cardiovascular and cerebrovascular events between transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) for severe aortic stenosis. Seventeen studies (n = 4,659) comparing TAVI (n = 2,267) and SAVR (n = 2,392) were included. End points were baseline logistic European System for Cardiac Operative Risk Evaluation score, all-cause mortality, cardiovascular mortality, myocardial infarction, stroke, transient ischemic attack, and major bleeding events. Mean differences or risk ratios with 95% conf...
Source: The American Journal of Cardiology - June 6, 2013 Category: Cardiology Authors: Hemang B. Panchal, Vatsal Ladia, Saurabh Desai, Tejaskumar Shah, Vijay Ramu Tags: Valvular Heart Disease Source Type: research
Comparison of the Efficacy and Safety of Two Rivaroxaban Doses in Acute Coronary Syndrome (from ATLAS ACS 2–TIMI 51)
In conclusion, the 2 doses of rivaroxaban reduced cardiovascular events in patients with recent acute coronary syndromes treated with antiplatelet therapies; however, the 2.5-mg dose was associated with lower mortality and fewer bleeding complications than the 5-mg dose. Thus, the addition of rivaroxaban 2.5 mg twice daily offers a more favorable balance of efficacy and safety in patients with recent acute coronary syndromes.
Source: The American Journal of Cardiology - May 28, 2013 Category: Cardiology Authors: Jessica L. Mega, Eugene Braunwald, Stephen D. Wiviott, Sabina A. Murphy, Alexei Plotnikov, Nina Gotcheva, Mikhail Ruda, C. Michael Gibson Tags: Coronary Artery Disease Source Type: research
Angina Pectoris or Myocardial Infarctions, Pulmonary Arteriovenous Malformations, Hereditary Hemorrhagic Telangiectasia, and Paradoxical Emboli
In conclusion, we suggest that in patients with untreated PAVMs, cardiac ischemia can occur because of a paradoxical embolus through PAVMs to a coronary artery.
Source: The American Journal of Cardiology - May 23, 2013 Category: Cardiology Authors: Katherine Clark, Reed E. Pyeritz, Scott O. Trerotola Tags: Miscellaneous Source Type: research
Thrombocytopenia in Patients With Atrial Fibrillation on Oral Anticoagulation Undergoing Percutaneous Coronary Intervention
In conclusion, mild to moderate baseline thrombocytopenia does not seem to have a clinically significant effect on bleeding or thrombotic or thromboembolic complications after PCI in these frail patients receiving multiple antithrombotic drugs.
Source: The American Journal of Cardiology - May 13, 2013 Category: Cardiology Authors: Tuomas Kiviniemi, Pasi Karjalainen, Andrea Rubboli, Axel Schlitt, Petri Tuomainen, Matti Niemelä, Mika Laine, Fausto Biancari, Gregory Y.H. Lip, K.E. Juhani Airaksinen Tags: Coronary Artery Disease Source Type: research
Comparative Analysis of Cardiovascular Disease Risk Factors Influencing Nonfatal Acute Coronary Syndrome and Ischemic Stroke
The aim of the present work was to compare the influence of classic cardiovascular disease (CVD) risk factors on the development of acute coronary syndrome (ACS) and ischemic stroke. During 2009–2010, 1,000 participants were enrolled: 250 were consecutive patients with a first ACS, 250 were consecutive patients with a first ischemic stroke, and 500 were population-based, control subjects, 1-for-1 matched to the patients by age and gender. The following CVD risk factors were evaluated: smoking/passive smoking, family history of CVD, physical inactivity, hypertension, hypercholesterolemia, diabetes mellitus, presence of ov...
Source: The American Journal of Cardiology - April 29, 2013 Category: Cardiology Authors: Christina-Maria Kastorini, Ekavi Georgousopoulou, Konstantinos N. Vemmos, Vassilios Nikolaou, Dimitrios Kantas, Haralampos J. Milionis, John A. Goudevenos, Demosthenes B. Panagiotakos Tags: Coronary Artery Disease Source Type: research
Between a Rock and a Hard Place: Weighing Thrombotic Risk Against Bleeding Complications
The prospect of a further reduction of thrombotic end points (stent thrombosis, acute coronary syndromes, ischemic stroke) may seem appealing and encouraging to clinicians, interventional cardiologists in particular. Be that as it may, are we willing to accept a further reduction in thrombotic events at the trade-off of increasing hemorrhagic risk?
Source: The American Journal of Cardiology - April 25, 2013 Category: Cardiology Authors: Bartosz Hudzik, Lech Polonski Tags: Readers' Comments Source Type: research
Troponin T in Acute Ischemic Stroke
In conclusion, elevated cTnT can be frequently detected in patients with AIS. To reliably identify patients with current acute myocardial impairment, more in-depth clinical investigation is needed.
Source: The American Journal of Cardiology - April 8, 2013 Category: Cardiology Authors: Michal Král, Daniel Šaňák, Tomáš Veverka, Martin Hutyra, David Vindiš, Anna Kunčarová, Andrea Bártková, Tomáš Dorňák, Marija Švábová, Veronika Kubíčková, Jana Zapletalová, Roman Herzig, David Školoudík Tags: Miscellaneous Source Type: research
Usefulness of Frequent Supraventricular Extrasystoles and a High CHADS2 Score to Predict First-Time Appearance of Atrial Fibrillation
Frequent supraventricular extrasystoles (SVEs) are associated with the subsequent first-time appearance of atrial fibrillation (AF) and ischemic stroke. The aim of this study was to investigate the combined role of SVEs and an AF-related risk score for ischemic stroke, the CHADS2 score, on the occurrence of new AF in patients in sinus rhythm. The Shinken Database 2004–2010 lists 3,263 patients who underwent 24-hour Holter monitoring. A total of 2,589 patients were analyzed, after excluding 674 patients previously diagnosed with AF. Frequent SVEs were defined as ≥102 beats/day (the top quartile) and the presence of a cl...
Source: The American Journal of Cardiology - March 18, 2013 Category: Cardiology Authors: Shinya Suzuki, Koichi Sagara, Takayuki Otsuka, Hiroto Kano, Shunsuke Matsuno, Hideaki Takai, Tokuhisa Uejima, Yuji Oikawa, Akira Koike, Kazuyuki Nagashima, Hajime Kirigaya, Junji Yajima, Hiroaki Tanabe, Hitoshi Sawada, Tadanori Aizawa, Takeshi Yamashita Tags: Arrhythmias and Conduction Disturbances Source Type: research
Relation of Serum Adiponectin Levels to Number of Traditional Atherosclerotic Risk Factors and All-Cause Mortality and Major Adverse Cardiovascular Events (from the Copenhagen City Heart Study)
Adiponectin exerts anti-inflammatory and antiatherogenic effects and appears to protect against arteriosclerosis. Accordingly, an association between low concentrations of plasma adiponectin and cardiovascular (CV) disease has been demonstrated in several studies. In contrast, elevated plasma adiponectin has been associated with increased mortality and an increasing number of major adverse CV events (MACE). Because of these conflicting results, the true role of adiponectin remains to be elucidated. In the Copenhagen City Heart Study, we prospectively followed up 5,624 randomly selected men and women from the community with...
Source: The American Journal of Cardiology - February 4, 2013 Category: Cardiology Authors: Soren Lindberg, Rasmus Mogelvang, Sune H. Pedersen, Mette Bjerre, Jan Frystyk, Allan Flyvbjerg, Søren Galatius, Jan Skov Jensen Tags: Preventive Cardiology Source Type: research
Safety of Continuous Anticoagulation With Dabigatran During Implantation of Cardiac Rhythm Devices
In conclusion, although no thromboembolic or major bleeding events were observed, additional studies are required to define the optimal antithrombotic management in the perioperative period.
Source: The American Journal of Cardiology - January 28, 2013 Category: Cardiology Authors: Christopher P. Rowley, Michael L. Bernard, William W. Brabham, Peter C. Netzler, Darren S. Sidney, Frank Cuoco, J. Lacy Sturdivant, Robert B. Leman, J. Marcus Wharton, Michael R. Gold Tags: Arrhythmias and Conduction Disturbances Source Type: research
Association of Serum Uric Acid and Cardiovascular Disease in Healthy Adults
In conclusion, the strong association of SUA levels with CVD in women, compared with the much lesser degree in men, highlights the necessity of stratifying by gender in investigations of cardiovascular risk factors and supports exploration of SUA as a marker of CVD risk in healthy populations.
Source: The American Journal of Cardiology - January 25, 2013 Category: Cardiology Authors: Shaye Kivity, Eran Kopel, Elad Maor, Fadi Abu-Bachar, Shlomo Segev, Yechezkel Sidi, David Olchovsky Tags: Preventive Cardiology Source Type: research
Renal Impairment in a “Real-Life” Cohort of Anticoagulated Patients With Atrial Fibrillation (Implications for Thromboembolism and Bleeding)
In conclusion, the presence of impaired renal function was closely related to thrombotic/vascular events, bleeding, and mortality in anticoagulated patients with AF. During follow-up, 1/5 of the patients had significant impairment in renal function. Importantly, normal or mild renal dysfunction at baseline did not exclude the subsequent development of severe renal dysfunction during the follow-up period.
Source: The American Journal of Cardiology - January 21, 2013 Category: Cardiology Authors: Vanessa Roldán, Francisco Marín, Hermógenes Fernández, Sergio Manzano-Fernández, Pilar Gallego, Mariano Valdés, Vicente Vicente, Gregory Y.H. Lip Tags: Arrhythmias and Conduction Disturbances Source Type: research
Frequency, Patient Characteristics, Treatment Strategies, and Resource Usage of Atrial Fibrillation (from the Italian Survey of Atrial Fibrillation Management ISAF Study)
In conclusion, in our study, the frequency of AF was 2 times greater than previously reported (approximately 0.90%), rate control was the most pursued treatment strategy, anticoagulants were still underused, and the success rate of AF ablation was lower than reported by referral centers.
Source: The American Journal of Cardiology - January 7, 2013 Category: Cardiology Authors: Massimo Zoni-Berisso, Alessandro Filippi, Maurizio Landolina, Ovidio Brignoli, Gaetano D'Ambrosio, Giampiero Maglia, Massimo Grimaldi, Giuliano Ermini Tags: Arrhythmias and Conduction Disturbances Source Type: research
