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Source: The American Journal of Cardiology
Condition: Ischemic Stroke
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Total 182 results found since Jan 2013.
Relation of Left Atrial Dysfunction to Ischemic Stroke in Patients With Coronary Heart Disease (from the Heart and Soul Study)
In conclusion, LA dysfunction is an independent risk factor for stroke or TIA, even in patients without baseline AF.
Source: The American Journal of Cardiology - March 5, 2014 Category: Cardiology Authors: Jonathan M. Wong, Christine C. Welles, Farnaz Azarbal, Mary A. Whooley, Nelson B. Schiller, Mintu P. Turakhia Tags: Arrhythmias and Conduction Disturbances Source Type: research
Impact of Increased Orifice Size and Decreased Flow Velocity of Left Atrial Appendage on Stroke in Nonvalvular Atrial Fibrillation
This study investigated whether a larger LAA orifice is related to decreased LAA flow velocity and stroke in nonvalvular AF. The dimension, morphology, and flow velocity of LAA were compared in patients with nonvalvular AF with (stroke group, n = 67, mean age 66 ± 9 years) and without ischemic stroke (no-stroke group, n = 151, mean age 56 ± 10 years). Compared with no-stroke group, the stroke group had larger LA dimension (4.7 ± 0.8 vs 4.2 ± 0.6 cm, p
Source: The American Journal of Cardiology - December 26, 2013 Category: Cardiology Authors: Jung Myung Lee, Jaemin Shim, Jae-Sun Uhm, Young Jin Kim, Hye-Jeong Lee, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung Tags: Arrhythmias and Conduction Disturbances Source Type: research
Risk of Stroke in Patients With High On-Clopidogrel Platelet Reactivity to Adenosine Diphosphate After Percutaneous Coronary Intervention
In conclusion, in patients with coronary artery disease undergoing PCI, the presence of HPR to adenosine diphosphate is a risk factor for stroke.
Source: The American Journal of Cardiology - March 17, 2014 Category: Cardiology Authors: Nevio Taglieri, Maria Letizia Bacchi Reggiani, Tullio Palmerini, Gabriele Ghetti, Francesco Saia, Pamela Gallo, Carolina Moretti, Gianni Dall'Ara, Cinzia Marrozzini, Antonio Marzocchi, Claudio Rapezzi Tags: Coronary Artery Disease Source Type: research
A Comparison of Atrial Fibrillation Monitoring Strategies after Cryptogenic Stroke (From the CRYSTAL AF Trial)
Ischemic stroke etiology remains undetermined in 30% of cases, leading to a diagnosis of cryptogenic stroke. Paroxysmal atrial fibrillation (AF) is a major cause of ischemic stroke but may go undetected with short periods of ECG monitoring. The Cryptogenic Stroke and Underlying Atrial Fibrillation trial (CRYSTAL AF) demonstrated that long-term ECG monitoring with insertable cardiac monitors (ICM) is superior to conventional follow-up in detecting AF in the cryptogenic stroke population. We evaluated the sensitivity and negative predictive value (NPV) of various external monitoring techniques within a cryptogenic stroke cohort.
Source: The American Journal of Cardiology - June 24, 2015 Category: Cardiology Authors: William C. Choe, Rod S. Passman, Johannes Brachmann, Carlos A. Morillo, Tommaso Sanna, Richard Bernstein, Vincenzo Di Lazzaro, Hans-Christoph Diener, Marilyn Rymer, Frank Beckers, Jodi Koehler, Paul D. Ziegler, CRYSTAL AF Investigators Source Type: research
A Comparison of Atrial Fibrillation Monitoring Strategies After Cryptogenic Stroke (from the Cryptogenic Stroke and Underlying AF Trial)
Ischemic stroke cause remains undetermined in 30% of cases, leading to a diagnosis of cryptogenic stroke. Paroxysmal atrial fibrillation (AF) is a major cause of ischemic stroke but may go undetected with short periods of ECG monitoring. The Cryptogenic Stroke and Underlying Atrial Fibrillation trial (CRYSTAL AF) demonstrated that long-term electrocardiographic monitoring with insertable cardiac monitors (ICM) is superior to conventional follow-up in detecting AF in the population with cryptogenic stroke.
Source: The American Journal of Cardiology - June 24, 2015 Category: Cardiology Authors: William C. Choe, Rod S. Passman, Johannes Brachmann, Carlos A. Morillo, Tommaso Sanna, Richard A. Bernstein, Vincenzo Di Lazzaro, Hans-Christoph Diener, Marilyn M. Rymer, Frank Beckers, Jodi Koehler, Paul D. Ziegler, CRYSTAL AF Investigators Tags: Arrhythmias and Conduction Disturbances Source Type: research
Relation of Low-Density Lipoprotein Cholesterol to Ischemic Stroke in Patients With Nonvalvular Atrial Fibrillation
Low-density lipoprotein cholesterol (LDL-C) has been demonstrated as an independent risk factor of ischemic stroke, but the association of LDL-C with ischemic stroke in patients with nonvalvular atrial fibrillation (AF) remains uncertain. Our objective was to explore whether LDL-C could refine stroke stratification in AF patients. A total of 424 nonvalvular AF patients with ischemic stroke and 391 ones without ischemic stroke were enrolled. No patient had received antithrombotic therapy. Multivariate logistic regression analysis showed that LDL-C was an independent predictor of ischemic stroke in AF patients, with the adju...
Source: The American Journal of Cardiology - January 24, 2017 Category: Cardiology Authors: Zhiyong Qi, Hua Chen, Zhichao Wen, Fei Yuan, Huanchun Ni, Wen Gao, Jun Shen, Jian Li, Yangyi Lin, Ying Shan, Bo Jin, Pingping Yan, Haiming Shi, Xinping Luo Source Type: research
Age-Related Disparity Trends in Stroke-Related Mortality in the United States, 1999 to 2019
Stroke hospitalizations and mortality have declined in older subjects in the United States; however, acute ischemic stroke hospitalizations have increased in subjects 25 to 64 years of age.1,2 Regardless of increasing acute ischemic stroke hospitalization trends in young patients, population-based estimates and trends of stroke (including hemorrhagic and ischemic stroke) related mortality stratified by age groups are currently scarce. Therefore, in this study, we assess ed trends in stroke mortality rates in varying age groups over 2 decades in the United States.
Source: The American Journal of Cardiology - February 28, 2022 Category: Cardiology Authors: Rochell Issa, Abdul Mannan Khan Minhas, Robert W. Ariss, Salik Nazir, Hiba Rehman, Waleed Tallat Kayani, Salim S. Virani Source Type: research
Gender-Specific Differences for Risk of Disability and Death in Atrial Fibrillation-Related Stroke
In this study, we examined patients with AF with ischemic stroke patient characteristics associated with increased stroke severity.
Source: The American Journal of Cardiology - October 6, 2016 Category: Cardiology Authors: Ryan C. Martin, W. Scott Burgin, Matthew B. Schabath, Bonnie Kirby, Sanders H. Chae, Michael G. Fradley, David Z. Rose, Arthur J. Labovitz Tags: Arrythmias and Conduction Disturbances Source Type: research
Underuse of oral anticoagulants in patients with ischemic stroke and atrial fibrillation in China
Anticoagulant therapy is an effective stroke prevention measure for people with atrial fibrillation (AF) who are at high risk of ischemic stroke. However, it is reported that oral anticoagulants (OACs) are generally underused in clinical practice. A better awareness of current usage of anticoagulant therapy would enable prevention of stroke secondary to AF. Therefore, we determined the nationwide prevalence of AF and the frequency of OACs use among patients with ischemic stroke in China. Based on the China National Stroke Screening Survey (CNSSS), a representative nationwide sample of 1,252,703 adults over 40 years old dur...
Source: The American Journal of Cardiology - September 13, 2018 Category: Cardiology Authors: Jian Guo, Tianjia Guan, Siyuan Fan, Baohua Chao, Longde Wang, Yuanli Liu Source Type: research
Meta-Analysis of Randomized Clinical Trials Comparing the Impact of Implantable Loop Recorder Versus Usual Care After Ischemic Stroke for Detection of Atrial Fibrillation and Stroke Risk
Implantable loop recorder (ILR) is recommended to detect subclinical atrial fibrillation (AF) after cryptogenic stroke; however, the clinical outcomes of this practice is unclear. We conducted a systematic review and meta-analysis of randomized controlled trials to evaluate 12-month AF detection, change in oral anticoagulation (OAC), and recurrent stroke in ILR versus usual care after ischemic stroke. We searched Medline, Embase, Web of Science, Cochrane Library for randomized controlled trials comparing ILR with usual care after any ischemic stroke.
Source: The American Journal of Cardiology - October 28, 2021 Category: Cardiology Authors: Darae Ko, Qiying Dai, David B. Flynn, Nicholas A. Bosch, Robert H. Helm, Kevin M Monahan, Charlotte Andersson, Christopher D. Anderson, Allan J. Walkey Source Type: research
Prevalence of and Risk Factors for Silent Ischemic Stroke in Patients With Atrial Fibrillation as Determined by Brain Magnetic Resonance Imaging
Varied silent ischemic stroke (SS) prevalence occurs in patients with atrial fibrillation (AF). Stroke history is worth 2 points in the CHADS2 scoring system. An unknown proportion of patients with AF with a CHADS2 score of 0 or 1 have been undertreated for stroke prevention. We investigated SS risk factors using magnetic resonance imaging and estimated SS impact on clinical outcomes in patients with AF. We analyzed a total of 1,200 patients (400 with AF and 800 with sinus rhythm) who had brain magnetic resonance imaging performed for routine health checkups. Clinical outcomes including symptomatic stroke, dementia, and co...
Source: The American Journal of Cardiology - November 25, 2013 Category: Cardiology Authors: Myung-jin Cha, Hyo Eun Park, Min-ho Lee, Youngjin Cho, Eue-keun Choi, Seil Oh Tags: Arrhythmias and Conduction Disturbances Source Type: research
Ischemic Stroke Occurring During Intercourse in Young Women on Oral Contraceptives
We present 2 cases of young women taking oral contraceptives, each presenting with an ischemic stroke. Transthoracic echocardiography revealed a patent foramen ovale in one patient and an atrial septal defect in the other. The most likely cause of stroke in both patients is embolic. Despite conflicting evidence, young patients presenting with ischemic stroke and found to have a patent foramen ovale or atrial septal defect should be considered for possible device-based closure.
Source: The American Journal of Cardiology - May 19, 2014 Category: Cardiology Authors: P. Elliott Miller, Lorrel Brown, Paras Khandheria, Jon R. Resar Tags: Case Report Source Type: research
Effect of Obstructive Sleep Apnea on Frequency of Stroke in Patients with Atrial Fibrillation
Obstructive sleep apnea (OSA) is an independent risk factor for ischemic stroke that is not included in the usual cardioembolic risk assessments for patients with atrial fibrillation (AF). The aim of this study was to investigate the impact of OSA on stroke rate in patients with AF. Patients with AF and new diagnosis of OSA were identified from retrospective chart review. Those with a history of stroke at the time of the sleep study were excluded. The primary outcome was the incidence of stroke, determined by a physician investigator blinded to the results of polysomnography.
Source: The American Journal of Cardiology - November 29, 2014 Category: Cardiology Authors: Dmitry M. Yaranov, Athanasios Smyrlis, Natalia Usatii, Amber Butler, Joann R. Petrini, Jose Mendez, Mark K. Warshofsky Source Type: research
Meta-Analysis of Anticoagulation Use, Stroke, Thromboembolism, Bleeding, and Mortality in Patients With Atrial Fibrillation on Dialysis
Atrial fibrillation (AF) is common in patients on dialysis. Although randomized trials of anticoagulation for AF have demonstrated striking reductions in stroke, these trials did not recruit patients on dialysis. We thus undertook this systematic review and meta-analysis of observational studies including patients with AF on dialysis that reported associations of anticoagulation use. Twenty studies involving 529,741 subjects and 31,321 patients with AF on dialysis were identified. Anticoagulation was associated with a 45% (95% CI 13% to 88%) increased risk of any stroke, reflecting a nonsignificant 13% (95% CI −4% to 34...
Source: The American Journal of Cardiology - April 12, 2016 Category: Cardiology Authors: Christopher X. Wong, Ayodele Odutayo, Connor A. Emdin, Ned J. Kinnear, Michelle T. Sun Tags: Arrhythmias and Conduction Disturbances Source Type: research
Usefulness of CHADS2 and CHA2DS2-VASc Scores for Stroke Prediction in Patients With Cancer and Atrial Fibrillation
Stroke prediction scores have not been validated in patients with cancer and Atrial Fibrillation (AF). We aimed to identify unique risk factors and evaluate validity of CHADS2 and CHA2DS2-VASc scores to predict risk of stroke and mortality. A retrospective review of all cancer patients with pre-existing AF presenting from 2008 to 2014 was performed. Outcomes included ischemic stroke and mortality. Prognostic factors were identified with Fine& Gray regression for stroke and Cox proportional hazards analysis for survival.
Source: The American Journal of Cardiology - September 19, 2017 Category: Cardiology Authors: Rushad Patell, Alejandra Gutierrez, Lisa Rybicki, Alok A. Khorana Source Type: research
