Filtered By:
Source: Thrombosis and Haemostasis

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 528 results found since Jan 2013.

Paediatric arterial ischaemic stroke and cerebral sinovenous thrombosis. First report from the Italian Registry of Pediatric Thrombosis (R. I. T. I., Registro Italiano Trombosi Infantili).
I. T. I. (Registro Italiano Trombosi Infantili) Abstract Data from large case series of children with cerebral thrombotic events are pivotal to improve prevention, early recognition and treatment of these conditions. The Italian Registry of Pediatric Thrombosis (R. I. T. I.) was established in 2007 by a multidisciplinary team, aiming for a better understanding of neonatal and paediatric thrombotic events in Italy and providing a preliminary source of data for the future development of specific clinical trials and diagnostic-therapeutic protocols. We analysed data relative to the paediatric cerebral throm...
Source: Thrombosis and Haemostasis - March 12, 2015 Category: Hematology Authors: Suppiej A, Gentilomo C, Saracco P, Sartori S, Agostini M, Bagna R, Bassi B, Giordano P, Grassi M, Guzzetta A, Lasagni D, Luciani M, Molinari AC, Palmieri A, Putti MC, Ramenghi LA, Rota LL, Sperlì D, Laverda AM, Simioni P, Stroke working group of the R.†Tags: Thromb Haemost Source Type: research

Association of Stroke Risk Biomarkers with Stroke Symptoms: The Reasons for Geographic And Racial Differences in Stroke Cohort.
CONCLUSIONS: Strong associations of stroke risk biomarkers with stroke symptoms in persons without a clinical history of cerebrovascular disease support a hypothesis that some of these stroke symptoms represent unrecognized cerebrovascular disease. Future work is needed to determine whether these biomarkers identify persons with stroke symptoms who have a particularly high stroke risk. This article is protected by copyright. All rights reserved. PMID: 27813265 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - November 3, 2016 Category: Hematology Authors: Landry KK, Alexander KS, Zakai NA, Judd SE, Kleindorfer DO, Howard VJ, Howard G, Cushman M Tags: J Thromb Haemost Source Type: research

ABO Blood Type and Stroke Risk: The REasons for Geographic and Racial Differences in Stroke (REGARDS) Study.
CONCLUSION: Blood type AB is associated with an increased risk of stroke that is not attenuated by conventional stroke risk factors and factor VIII levels were associated with 60% of the association. While blood type AB is rare in the U.S. population, it is a significant stroke risk factor and may play an important role in stroke risk in these individuals. This article is protected by copyright. All rights reserved. PMID: 24444093 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - January 21, 2014 Category: Hematology Authors: Zakai NA, Judd SE, Alexander K, McClure LA, Kissela BM, Howard G, Cushman M Tags: J Thromb Haemost Source Type: research

Multiple risk factors and ischaemic stroke in the elderly Asian population with and without atrial fibrillation. An analysis of 425,600 Chinese individuals without prior stroke.
In conclusion, an increasing cluster of multiple cardiovascular risk factors (besides AF) contributes to a greater risk for ischaemic stroke, especially in the elderly population. If elderly and with multiple risk factors, non-AF patients may have a risk of incident ischaemic stroke that is comparable or even higher than patients with AF, suggesting that the incremental stroke risk attributable to AF is marginal in such 'high risk' patients. PMID: 26322338 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - August 31, 2015 Category: Hematology Authors: Guo Y, Wang H, Tian Y, Wang Y, Lip GY Tags: Thromb Haemost Source Type: research

Procarboxypeptidase U (proCPU, TAFI, proCPB2) in cerebrospinal fluid during ischemic stroke is associated with stroke progression, outcome and blood-brain barrier dysfunction.
CONCLUSIONS: ProCPU is increased in CSF during hyperacute ischemic stroke and are associated with stroke progression and outcome after 3 months, most likely due to BBB dysfunction in the hyperacute phase of ischemic stroke. This article is protected by copyright. All rights reserved. PMID: 29194929 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - December 1, 2017 Category: Hematology Authors: Mertens JC, Leenaerts D, Brouns R, Engelborghs S, Ieven M, De Deyn PP, Lambeir AM, Hendriks D Tags: J Thromb Haemost Source Type: research

Comorbidity and the increased mortality after hospitalization for stroke: a population-based cohort study.
CONCLUSION: Comorbidity, notably cancer and advanced renal or liver disease, increased one-year mortality after stroke beyond the combined effects expected from either disease acting alone. This article is protected by copyright. All rights reserved. PMID: 29171148 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - November 23, 2017 Category: Hematology Authors: Corraini P, Szépligeti SK, Henderson VW, Ording AG, Horváth-Puhó E, Sørensen HT Tags: J Thromb Haemost Source Type: research

Preadmission use of Glucocorticoids and Risk of Cardiovascular Events in Patients with Ischemic Stroke.
CONCLUSIONS: During the first year after ischemic stroke, current glucocorticoid use was associated with moderately increased risk of myocardial infarction and venous thromboembolism and lower risk of hemorrhagic stroke, while the risk of recurrent ischemic stroke was not affected. This article is protected by copyright. All rights reserved. PMID: 30179297 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - September 4, 2018 Category: Hematology Authors: Sundbøll J, Darvalics B, Horváth-Puhó E, Adelborg K, Laugesen K, Schmidt M, Henderson VW, Sørensen HT Tags: J Thromb Haemost Source Type: research

Stroke-induced hexokinase 2 in circulating monocytes exacerbates vascular inflammation and atheroprogression
CONCLUSIONS: Stroke-induced monocyte Hk2 upregulation is a key mechanism underlying post-stroke vascular inflammation and atheroprogression.PMID:36893911 | DOI:10.1016/j.jtha.2023.02.021
Source: Thrombosis and Haemostasis - March 9, 2023 Category: Hematology Authors: Yang Sun Lujun Zhang Yu Cao Xingsheng Li Fan Liu Xiaoxiao Cheng Jianlin Du Haitao Ran Zhigang Wang Yongyong Li Yuxing Feng Liwen Liang Wenhua Su N D Melgiri Hong Zhang Rongzhong Huang Source Type: research

Predicting Adverse Events beyond Stroke and Bleeding with the ABC-Stroke and ABC-Bleeding Scores in Patients with Atrial Fibrillation: The Murcia AF Project.
CONCLUSION:  In AF patients, the ABC-stroke and ABC-bleeding scores demonstrated similar predictive ability for outcomes beyond stroke and bleeding, including MI, acute HF, a composite of cardiovascular events, and all-cause deaths. This is consistent with nonspecificity of biomarkers that predict "sick" patients or poor prognosis overall. PMID: 32506417 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - June 6, 2020 Category: Hematology Authors: Camelo-Castillo A, Rivera-Caravaca JM, Marín F, Vicente V, Lip GYH, Roldán V Tags: Thromb Haemost Source Type: research

Comparison of risk of serious cardiovascular events after haemorrhagic versus ischaemic stroke: a population-based study
CONCLUSIONS: The risk of subsequent cardiovascular events is similar between patients with incident haemorrhagic or ischaemic stroke. Patients with previous haemorrhagic stroke should be regarded as a population at very-high risk of subsequent CVD.PMID:35688459 | DOI:10.1055/a-1873-9092
Source: Thrombosis and Haemostasis - June 10, 2022 Category: Hematology Authors: Ralph Kwame Akyea Georgios Georgiopoulos Barbara Iyen Joe Kai Nadeem Qureshi George Ntaios Source Type: research

D-dimer and the Risk of Stroke and Coronary Heart Disease. The REasons for Geographic and Racial Differences in Stroke (REGARDS) Study.
Abstract D-dimer, a biomarker of coagulation, is higher in blacks than in whites and has been associated with stroke and coronary heart disease (CHD). It was our objective to assess the association of higher D-dimer with stroke and CHD in blacks and whites. REGARDS recruited 30,239 black and white participants across the contiguous US and measured baseline D-dimer in stroke (n=646) and CHD (n=654) cases and a cohort random sample (n=1,104). Cox models adjusting for cardiovascular risk factors determined the hazard ratio (HR) for increasing D-dimer for cardiovascular disease with bootstrapping to assess the differe...
Source: Thrombosis and Haemostasis - December 21, 2016 Category: Hematology Authors: Zakai NA, McClure LA, Judd SE, Kissela B, Howard G, Safford M, Cushman M Tags: Thromb Haemost Source Type: research

Targeting von Willebrand Factor in Ischaemic Stroke: Focus on Clinical Evidence.
Abstract Despite great efforts in stroke research, disability and recurrence rates in ischaemic stroke remain unacceptably high. To address this issue, one potential target for novel therapeutics is the glycoprotein von Willebrand factor (vWF), which increases in thrombogenicity especially under high shear rates as it bridges between vascular sub-endothelial collagen and platelets. The rationale for vWF as a potential target in stroke comes from four bodies of evidence. (1) Animal models which recapitulate the pathogenesis of stroke and validate the concept of targeting vWF for stroke prevention and the use of the...
Source: Thrombosis and Haemostasis - May 31, 2018 Category: Hematology Authors: Buchtele N, Schwameis M, Gilbert JC, Schörgenhofer C, Jilma B Tags: Thromb Haemost Source Type: research