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Source: Clinical Research in Cardiology
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Total 257 results found since Jan 2013.
Treatment of patients with multiple organ dysfunction syndrome (MODS) with an electromagnetic field coupled to biorhythmically defined impulse configuration: the MicrocircMODS study
ConclusionPVT treatment was feasible and safe and could be performed without obstruction of standard patient care. An increase in microcirculatory blood flow, a rapid reduction in vasopressor use, and an improvement in global haemodynamics paralleled PVT treatment. Findings of this pilot study allowed forming a concept for a randomized trial for further proof.Graphical abstract
Source: Clinical Research in Cardiology - September 17, 2023 Category: Cardiology Source Type: research
Temporal trends of case-fatality in patients undergoing dual-injection coronary chronic total occlusion recanalization
ConclusionAnnual number of CTO procedures performed in Germany increased from 2009 to 2020 with a concomitant anti-proportional decrease in the case-fatality. Our findings may help to draw more attention to predictors of in-hospital case fatality in patients hospitalized for CTO recanalization.Graphical abstract
Source: Clinical Research in Cardiology - September 11, 2023 Category: Cardiology Source Type: research
Detection of atrial fibrillation using an implantable loop recorder in patients with previous cryptogenic stroke: the SPIDER-AF registry (Stroke Prevention by Increasing DEtection Rates of Atrial Fibrillation)
ConclusionsIn the context of cryptogenic strokes ILRs are a valuable tool for early detection of AF. In a real-world scenario, the anticoagulation therapy remains inadequate despite diagnosed AF in a relevant subset of patients requiring optimization of patient management.Graphical abstract
Source: Clinical Research in Cardiology - August 23, 2023 Category: Cardiology Source Type: research
Protective effect of vaccination on the risk of cardiovascular disease after SARS-CoV-2 infection
ConclusionAlthough COVID-19 increased the CVD risk, the inverse association in the risk of CVDs according to vaccine doses was significant in a dose –response manner. Our findings suggest that ≥ second doses of the COVID-19 vaccine prevent the risk of CVDs after SARS-CoV-2 infection.Graphical abstractIn 2,146,130 infected adults ( ≥ 20 years), the inverse association in the short-term risk of cardiovascular diseases, including coronary heart disease and stroke, according to vaccine doses received was significant in a dose–response manner.
Source: Clinical Research in Cardiology - July 31, 2023 Category: Cardiology Source Type: research
Feasibility and outcome of third-generation transcatheter aortic valve implantation in patients with extra-large aortic annulus
ConclusionTreatment of ELA patients with third-generation TAVI prostheses is feasible and safe, providing similar device success and complication rates as in matched controls with regular-sized aortic annulus. Post-interventional pacemaker implantation rates were low compared to the control group, yet incidence of moderate PVL remains problematic in ELA patients.
Source: Clinical Research in Cardiology - July 31, 2023 Category: Cardiology Source Type: research
Protective effect of vaccination on the risk of cardiovascular disease after SARS-CoV-2 infection
ConclusionAlthough COVID-19 increased the CVD risk, the inverse association in the risk of CVDs according to vaccine doses was significant in a dose –response manner. Our findings suggest that ≥ second doses of the COVID-19 vaccine prevent the risk of CVDs after SARS-CoV-2 infection.Graphical abstractIn 2,146,130 infected adults ( ≥ 20 years), the inverse association in the short-term risk of cardiovascular diseases, including coronary heart disease and stroke, according to vaccine doses received was significant in a dose–response manner.
Source: Clinical Research in Cardiology - July 31, 2023 Category: Cardiology Source Type: research
New-onset atrial fibrillation after percutaneous patent foramen ovale closure: a meta-analysis
ConclusionPercutaneous PFO closure led to higher AF post-procedural incidence compared to the conservative strategy. Heterogeneity in surveillance and follow-up strategy limited the generalizability.Trial RegistrationRegistered on PROSPERO (CRD42022359945).Graphical abstract
Source: Clinical Research in Cardiology - July 29, 2023 Category: Cardiology Source Type: research
A meta-analysis evaluating efficacy and safety of colchicine for prevention of major cardiovascular events in patients with coronary artery disease
ConclusionsColchicine is an effective, relatively safe drug that could be considered for the treatment of CAD. However, we need to pay attention to the increasing occurrence of non-cardiovascular mortality and infection especially pneumonia possibly caused by colchicine.Graphical abstractEfficacy and safety of colchicine for patients with CAD.CAD coronary artery disease;RCTs randomized controlled trials;OR odds ratio;MACEs major adverse cardiovascular events;ACS acute coronary syndrome;NNT number needed to treat;NNH number needed to harm
Source: Clinical Research in Cardiology - July 28, 2023 Category: Cardiology Source Type: research
Five-year-outcome of new-onset perioperative atrial fibrillation after left atrial appendage amputation concomitant with cardiac surgery
ConclusionPOAF is associated with a higher rate of the combined endpoint of all-cause mortality, stroke and rehospitalization. The composite endpoint in patients with LAA-amputation concomitant with OPCAB surgery developing new-onset POAF in a 5-year follow-up was not increased compared to a control cohort maintaining sinus rhythm.Graphical abstractFive-year outcome of patients with POAF and LAA-amputation;95% CI, 95% confidence interval,CPR, cardiopulmonary resuscitation,ECLS, extracorporeal life support,HR, hazard ratio,IABP, intra-aortic balloon pump,LAA, left atrial appendage,OPCAB, off-pump coronary artery bypass graf...
Source: Clinical Research in Cardiology - July 10, 2023 Category: Cardiology Source Type: research
