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Source: Clinical Research in Cardiology
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Total 257 results found since Jan 2013.
Nighttime hemodynamic phenotype. A novel risk factor for cardiovascular disease, especially heart failure: the practitioner-based nationwide JAMP study
ConclusionNighttime non-dipper and riser patterns of heart rate were associated with CVD especially HF, independently and additively of nocturnal BP dipping status, indicating the importance of antihypertensive strategies targeting nighttime hemodynamics.Clinical trial registrationURL:https://www.umin.ac.jp/ctr/; Unique identifier: UMIN000020377.Graphical abstract
Source: Clinical Research in Cardiology - June 27, 2022 Category: Cardiology Source Type: research
Clonal hematopoiesis of indeterminate potential in patients with acute coronary syndrome undergoing percutaneous coronary intervention in the absence of traditional risk factors
ConclusionThe most frequent CHIP-related mutations,DNMT3A, TET2, andASXL1 are significantly associated with increased risk of recurrent cardiovascular events. Our study may be valuable target to reduce residual risk in patients with ACS carrying specific mutations.Graphical abstract
Source: Clinical Research in Cardiology - June 15, 2022 Category: Cardiology Source Type: research
Catheter ablation of supraventricular tachycardia in patients with and without structural heart disease: insights from the German ablation registry
ConclusionPatients with and without SHD undergoing SVT ablation exhibit similar success rates and low major complication rates, despite disadvantageous baseline characteristics in SHD patients. These data highlight the safety and efficacy of SVT ablation in patients with and without SHD. Nevertheless Kaplan –Meier mortality estimates at 1 year demonstrate a significant mortality increase in patients with SHD, highlighting the importance of treating the underlying condition and reliable anticoagulation if indicated.
Source: Clinical Research in Cardiology - April 29, 2022 Category: Cardiology Source Type: research
Impact of atrial fibrillation pattern on outcomes after left atrial appendage closure: lessons from the prospective LAARGE registry
ConclusionAtrial fibrillation type did not impair periprocedural safety or in-hospital MACE patients undergoing LAAC. However, after one year, NPAF was associated with higher mortality.Graphic abstract
Source: Clinical Research in Cardiology - April 29, 2022 Category: Cardiology Source Type: research
Impact of early ablation of atrial fibrillation on long-term outcomes: results from phase II/III of the GLORIA-AF registry
ConclusionsEarly AF ablation in a contemporary prospective cohort of AF patients who were predominantly treated with NOACs was associated with a survival advantage compared to medical therapy alone.Trial registrationClinical trial registration:http://www.clinicaltrials.gov. Unique identifiers: NCT01468701, NCT01671007 and NCT01937377.Graphical abstractCreated with BioRender.com.
Source: Clinical Research in Cardiology - April 29, 2022 Category: Cardiology Source Type: research
Association of pulmonary vein isolation and major cardiovascular events in patients with atrial fibrillation
ConclusionsIn our matched comparison, patients in the PVI group had a lower incidence rate of all-cause mortality and hospital admission for acute heart failure compared to the non-PVI group.ClinicalTrials.gov IdentifierNCT02105844, April 7th 2014.Graphical abstract
Source: Clinical Research in Cardiology - April 11, 2022 Category: Cardiology Source Type: research
Clinical cardiovascular phenotypes and the pattern of future events in patients with type 2 diabetes
ConclusionsIn T2D, a patient ’s cardiovascular phenotype can help predict the pattern of future cardiovascular events.Graphical abstract
Source: Clinical Research in Cardiology - April 8, 2022 Category: Cardiology Source Type: research
Machine learning in the detection and management of atrial fibrillation
AbstractMachine learning has immense novel but also disruptive potential for medicine. Numerous applications have already been suggested and evaluated concerning cardiovascular diseases. One important aspect is the detection and management of potentially thrombogenic arrhythmias such as atrial fibrillation. While atrial fibrillation is the most common arrhythmia with a lifetime risk of one in three persons and an increased risk of thromboembolic complications such as stroke, many atrial fibrillation episodes are asymptomatic and a first diagnosis is oftentimes only reached after an embolic event. Therefore, screening for a...
Source: Clinical Research in Cardiology - March 30, 2022 Category: Cardiology Source Type: research
TAVI in patients with low-flow low-gradient aortic stenosis –short-term and long-term outcomes
ConclusionsWhile 3-year mortality remains high after TAVI in LFLG compared to HG patients, symptoms improve in all subsets after TAVI.Graphical abstract
Source: Clinical Research in Cardiology - March 23, 2022 Category: Cardiology Source Type: research
