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Source: Neurological Research
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Total 488 results found since Jan 2013.
Atherosclerotic plaque burden of middle cerebral artery and extracranial carotid artery characterized by MRI in patients with acute ischemic stroke in China: association and clinical relevance.
CONCLUSION: Greater atherosclerotic plaque burden and a closer association with stroke severity were found for the MCA as compared to the ipsilateral ECA. Identification of MCA plaque lesions by MRI may be helpful for developing more aggressive strategies for stroke prevention.
PMID: 28136710 [PubMed - as supplied by publisher]
Source: Neurological Research - February 2, 2017 Category: Neurology Tags: Neurol Res Source Type: research
Predictors of dependence after MCA ischemic stroke submitted to thrombolysis.
DISCUSSION: .Dependence is an important indicator of the efficacy of stroke care. Besides it was not possible to evaluate rehabilitation, this is the first study on predictors of post-stroke dependence that focus exclusively on patients with first-ever MCA IS submitted to IVT. NIHSS, LAA stroke, in-hospital pneumonia and seizures after discharge were associated with dependence after first-ever MCA IS submitted to IVT.
PMID: 29125072 [PubMed - as supplied by publisher]
Source: Neurological Research - November 11, 2017 Category: Neurology Tags: Neurol Res Source Type: research
Mild focal hypothermia regulates the dynamic polarization of microglia after ischemic stroke in mice.
Conclusions Hypothermia is protective following ischemic stroke and can reduce brain tissue loss. Moreover, hypothermia shifts the polarization of microglia from the M1 to the M2 phenotype in the ischemic mice brain. This observed biological phenomenon may partially explain the protective effects seen due to hypothermia in acute ischemic stroke.
PMID: 29619889 [PubMed - as supplied by publisher]
Source: Neurological Research - April 7, 2018 Category: Neurology Tags: Neurol Res Source Type: research
Association study of CACNA1C polymorphisms with large artery atherosclerotic stroke in Chinese Han population.
Conclusion The results suggested that there was a potential association between CNCNA1C gene and the risk factor of LAA stroke in Chinese Han population.
PMID: 29683785 [PubMed - as supplied by publisher]
Source: Neurological Research - April 24, 2018 Category: Neurology Tags: Neurol Res Source Type: research
Pathogenesis of epileptic seizures and epilepsy after stroke.
Authors: Yang H, Rajah G, Guo A, Wang Y, Wang Q
Abstract
Stroke is an important cause of seizures and epilepsy in adults, particularly among the elderly. The incidence of stroke increases yearly as life expectancy increases and the number of patients with post-stroke seizures and epilepsy is also rising. Post-stroke epilepsy accounts for nearly 50% of newly diagnosed epilepsy among patients over 60 years of age. With increasing stroke awareness and advanced treatments, increased attention is paid to post-stroke seizures and epilepsy including its diagnosis and treatment. There has been a plethora of research on th...
Source: Neurological Research - April 24, 2018 Category: Neurology Tags: Neurol Res Source Type: research
Effect of renal function on association between uric acid and prognosis in acute ischemic stroke patients with elevated systolic blood pressure.
CONCLUSION: The present study suggests that high serum uric acid concentration is associated with better prognosis in ischemic stroke patients with normal renal function, but not in those with abnormal renal function. The establishment of causality between increased uric acid levels and better stroke prognosis needs more suitably designed randomized clinical trials.
PMID: 32657261 [PubMed - as supplied by publisher]
Source: Neurological Research - July 15, 2020 Category: Neurology Tags: Neurol Res Source Type: research
Relationship between ischemic stroke locations, etiology subtypes, neurological outcomes, and autonomic cardiac function.
CONCLUSIONS: HRV measured after admission is related to the AIS infarction basin, TOAST subtypes, and neurological outcomes at discharge suggesting a possible role for HRV in evaluating AIS and identifying high-risk patients.
PMID: 32701421 [PubMed - as supplied by publisher]
Source: Neurological Research - July 25, 2020 Category: Neurology Tags: Neurol Res Source Type: research
Relationship between methylenetetrahydrofolate reductase (MTHFR) gene (A1298C) polymorphism with the risk of stroke: A systematic review and meta-analysis.
Authors: Kumar A, Sharma R, Misra S, Nath M, Kumar P
Abstract
Studies on relationship between methylenetetrahydrofolate reductase gene (MTHFR) gene A1298C polymorphism with the risk of ischemic as well as hemorrhagic stroke have shown discordant results. Present meta-analysis was aimed to clarify the relationship between MTHFR gene A1298C polymorphism with risk of stroke. A comprehensive literature search for all published articles was performed in electronic database including PubMed, EMbase, Cochrane Library, Trip Databases, Worldwide Science, CINAHL, and Google Scholar up to 31st December 2019. Pooled odds r...
Source: Neurological Research - August 1, 2020 Category: Neurology Tags: Neurol Res Source Type: research
The prognostic significance of the lipid profile after an ischemic stroke
CONCLUSIONS: The complete analysis of the lipid panel allows the determination of the prognosis of patients who suffered a stroke.PMID:34396927 | DOI:10.1080/01616412.2021.1967677
Source: Neurological Research - August 16, 2021 Category: Neurology Authors: Bruno Kusznir Vitturi Rubens Jos é Gagliardi Source Type: research
Intracranial arterial stenosis and recurrence in stroke patients with different risk stratifications by Essen stroke risk score
CONCLUSION: ICAS was an independent predictor of both 3- and 12-month stroke recurrence in low-risk but not high-risk patients with minor ischemic stroke or transient ischemic attack according to ESRS stratification.PMID:37724803 | DOI:10.1080/01616412.2023.2257415
Source: Neurological Research - September 19, 2023 Category: Neurology Authors: Yue Suo Jing Jing Xia Meng Zixiao Li Yuesong Pan Hongyi Yan Yong Jiang Liping Liu Xingquan Zhao Yilong Wang Hao Li Yongjun Wang CHANCE investigators Source Type: research
Exercise rehabilitation immediately following ischemic stroke exacerbates inflammatory injury.
CONCLUSION: Post-stroke exercise, if too early, may result in elevated levels of cell stress and increased expression of pro-inflammatory cytokines, which may amplify the tissue damage associated with cerebral ischemia/reperfusion injury. The results shed light on the manner in which exercise initiation timing may affect post-stroke rehabilitation.
PMID: 28415917 [PubMed - as supplied by publisher]
Source: Neurological Research - April 20, 2017 Category: Neurology Tags: Neurol Res Source Type: research
Genetic polymorphisms of vitamin D3 metabolizing CYP24A1 and CYP2R1 enzymes in Turkish patients with ischemic stroke.
Conclusion This is the first study conducted regarding the association of CYP24A1 rs927650 and CYP2R1 rs10741657 genetic polymorphisms and ischemic stroke risk. The polymorphic genotypes of these polymorphisms, together with hypertension, diabetes, smoking, and obesity, were found as significant risk factors for ischemic stroke.
PMID: 29528271 [PubMed - as supplied by publisher]
Source: Neurological Research - March 14, 2018 Category: Neurology Tags: Neurol Res Source Type: research
Effects of cerebral small vessel disease on the outcome of patients with ischemic stroke caused by large artery atherosclerosis.
DISCUSSION: CSVD can significantly influence the clinical outcome of stroke in patients with cerebral infarction caused by LAA, and the methods to capture whole brain CSVD burden cross the spectrum of changes in CSVD imaging features may be useful for patient stratification in clinical trials. Further studies should be performed to validate the relationship between CSVD related brain damage and LAA stroke.
PMID: 29543130 [PubMed - as supplied by publisher]
Source: Neurological Research - March 20, 2018 Category: Neurology Tags: Neurol Res Source Type: research
