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Source: Heart Rhythm

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Total 406 results found since Jan 2013.

B-po05-005 multi-physics, patient-specific computational modeling of la electrophysiology, biomechanics and hemodynamics reveals mechanistic connections between fibrotic remodeling and thrombosis risk
Fibrosis is a relevant clinical factor involved in AF and stroke, but it remains impossible to predict how a given fibrosis pattern disrupts left atrial (LA) electrophysiology (EP), wall motion, and blood flow in a biophysically integrative manner.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Alejandro Gonzalo, Christoph M. Augustin, Manuel Garc ía-Villalba, Pablo Martínez-Legazpi, Oscar Flores, Javier Bermejo, Elliot McVeigh, Andrew M. Kahn, Gernot Plank, Nazem Akoum, Juan C. del Álamo, Patrick Boyle Source Type: research

B-po05-197 increased use of direct-acting oral anticoagulants and anticoagulation rates in a large health care system
Oral anticoagulation (OAC) has been underused in patients with atrial fibrillation (AF) at risk for stroke. Data from registries has shown OAC rates in eligible patients of 50-60%. The use of direct oral anticoagulants (DOACs) has improved OAC rates but contemporary data are lacking.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: John V. Wylie, Michael V. Orlov Source Type: research

B-po04-162 risk of recurrent stroke with runs of supraventricular tachycardia and premature atrial contraction burden
Ischemic strokes are a significant cause of mortality in the United States, leading to roughly 140,000 deaths per year. Approximately one third are classified as cryptogenic. Previous studies have shown premature atrial contractions (PAC) and short runs of supraventricular tachycardia (SVT) increase the risk of stroke.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Weston Harkness, Jeff M. Hsing, Julie Davidson Source Type: research

B-po04-147 trends in early stroke and mortality in epicardial versus endocardial left atrial appendage closure in atrial fibrillation: nationwide readmissions database 2016-2018
Percutaneous left atrial appendage closure (LAAC) devices have emerged as an important alternative to anticoagulation for stroke prevention in patients with atrial fibrillation. National data on recent trends and early complication rates associated with endocardial (endo) LAAC and epicardial (epi) LAAC procedures are limited.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Edward V. Kogan, Christopher F. Liu, Shing C. Wong, Geoffrey W. Bergman, James E. Ip, George Thomas, Steven M. Markowitz, Bruce B. Lerman, Luke Kim, Jim W. Cheung Source Type: research

B-po04-143 safety and feasibility of reactive atrial-based anti-tachycardia pacing algorithm in cardiovascular implantable electronic devices to suppress atrial fibrillation in patients with left atrial appendage closure device
Reactive atrial-based anti-tachycardia pacing (rATP) in CIED (cardiovascular implantable electronic devices) are effective in AF suppression. Uninterrupted systemic anticoagulation is mandated when these algorithms are activated to avoid stroke and systemic thromboembolism. However, the use of rATP algorithm in patients with left atrial appendage (LAA) closure device without ongoing anticoagulation has not been studied.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Rayan El-Zein, Jordan Luli, Ishmail Saccoh, Cody Carter, Mitchell Stelzer, Emily M. Gates, Zeryab Khan, Ankur N. Shah, James M. Kleman, Sreedhar R. Billakanty, Anish K. Amin, Nagesh Chopra Source Type: research

B-po04-141 left atrial appendage occlusion versus oral anticoagulation as primary strategies to prevent laa thrombus and stroke following left atrial appendage electrical isolation: apropensity score-matched analysis
Left atrial appendage electrical isolation (LAAEI) has been shown to be an effective strategy in catheter ablation (CA) for atrial fibrillation (AF). However, its widespread adaptability is limited because patients must be on lifelong oral anticoagulation (OAC) irrespective of their CHA2DS2VASc score and due to some concerns about increased risk of thromboembolic events (TE) despite OAC.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Jorge Romero, Dhanunjaya R. Lakkireddy, Isabella Alviz, Juan C. Diaz, David F. Briceno, Abhishek Jaiswal, Alejandro Velasco, Carolina R. Valencia, Dalvert Polanco, Daniel Rodriguez, Mohamed Gabr, Joseph Karpenos, Chintan G. Trivedi, Sanghamitra Mohanty, Source Type: research

B-po05-154 an updated meta-analysis comparing left atrial appendage closure and oral anticoagulation
Left atrial appendage closure (LAAC) trials such as PREVAIL and PROTECT revealed non-inferiority of LAAC compared to warfarin. The recently published PRAGUE study showed that LAAC was non-inferior to direct oral anti-coagulants. Current guidelines give a IIb recommendation for LAAC in patients with non-valvular atrial fibrillation (NVAF) with increased risk of stroke and contraindication to long-term anticoagulation.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Sisir Siddamsetti, Arshad Muhammad Iqbal, Alexander Shinn, Sandeep Gautam Source Type: research

B-po05-153 quarterly versus annual ecg screening for atrial fibrillation in older chinese
Screening for atrial fibrillation before symptoms manifested and subsequent initiation of oral anticoagulants (OACs), could prevent stroke and death. The most cost-effective strategy to screen atrial fibrillation in high-risk population aged 65 and over remains unknown.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Wei Zhang, Yi Chen, Ji-Guang Wang Source Type: research

B-po04-115 hypertension and abnormal renal function increased the risk of ischemic stroke in anticoagulated ehra type-1 valvular atrial fibrillation
Atrial fibrillation (AF) increases the risk of stroke substantially, therefore many scores have been developed to risk stratify these patients. However, most of the previous studies have focused on non-valvular AF. The most widely used risk stratification score is the CHA2DS2-VASC score. Unfortunately, the validation of this score in valvular AF is poor.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Rena Winanti, Sunu Budhi Raharjo, Rina Ariani, Dicky A. Hanafy, Celly Anantaria Atmadikoesoemah, Prima Almazini, Yoga Yuniadi Source Type: research

B-po05-145 contemporary clinical and economic outcomes among oral anticoagulant treated and untreated elderly patients with atrial fibrillation
Oral anticoagulants (OACs) are the standard of care for decreasing stroke risk in atrial fibrillation (AF) patients.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Muhammad Bilal Munir, Patrick Hlavacek, Allison Keshishian Jennifer Guo, Rajesh Mallampati Mauricio Ferri, Cristina Russ Birol Emir, Matthew Cato, Huseyin Yuce, Jonathan C. Hsu Source Type: research

B-po05-144 comparing sodium glucose cotransporter 2 inhibitors and dipeptidyl peptidase-4 inhibitors on new-onset atrial fibrillation and ischemic stroke
Given the susceptibility of patients with type 2 diabetes mellitus towards cerebrovascular complications, there is increasing research on the cerebrovascular-protective effects of novel anti-diabetic agents. However, few studies have compared sodium glucose cotransporter-2 inhibitor (SGLT2I) and dipeptidyl peptidase-4 inhibitor (DPP4I) in their effects on stroke and atrial fibrillation (AF).
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Sharen Lee, Jiandong Zhou, Xiansong Wang, Carlin Chang, Tong Liu, Dong Chang, Wing Tak Wong, William K.K. Wu, Bernard M.Y. Cheung, Gary Tse, Qingpeng Zhang Source Type: research

B-po05-142 atrial fibrillation patient with low cha2ds2vasc score may still benefit from oral anticoagulation therapy for ischemic stroke prevention: the need to refine stroke risk assessment scores
The CHA2DS2VASC score has shown limitations in the assessment of ischemic stroke (IS) risk in atrial fibrillation (AF) patients.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Lilas Dagher, Abdel Hadi El Hajjar, Hunter Edward Launer, Christopher Pottle, Aneesh Dhore Tarek Ayoub, Nassir F. Marrouche Source Type: research

B-po05-139 changes in flow dynamics due to persistent atrial fibrillation in a chronically paced canine model
Atrial Fibrillation (AF) increases the risk of stroke, presumably because poor left atrial (LA) contraction leads to impaired blood flow and the potential for clots to form. Previous studies have not looked at flow changes over the course of AF progression.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Eugene Kwan, Jiawei Dong, Saranyu Thanasitsomboon, Orvelin Roman Elliott Hurd, Lucas Timmins Jason Mendes, Edward DiBella, Robert MacLeod, Derek J. Dosdall, Ravi Ranjan Source Type: research

B-po05-086 structural and tissue remodeling of the left atrium and left atrial appendage after atrial fibrillation ablation
Large left atrium appendage (LAA) orifice area and an increased left atrium (LA) volume have been associated with an increased risk of ischemic stroke. Catheter ablation (CA) of atrial fibrillation (AF) leads to anatomical and tissue changes within the LA and LAA.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Yichi Zhang, Lilas Dagher, Abdel Hadi El Hajjar, Aneesh Dhore, Alan Morris, Eugene Kholmovski, Chao Huang, Raman Danrad, Tarek Ayoub, Nassir Marrouche Source Type: research

B-po05-059 left atrial appendage occlusion (laao) using watchman device in end stage renal disease: analysis from national inpatient sample
Percutaneous occlusion of left atrial appendage (LAAC) using WATCHMAN device is a widely accepted alternative to oral anticoagulants to prevent ischemic stroke in atrial fibrillation. There is limited data regarding the utilization and safety of this intervention in patients with ESRD.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Shakeel Jamal, Ehizogie Edigin, Asim Kichloo, Zulfiqar Qutrio Baloch, Sardar Hassan Ijaz, Abdul Mannan Khan Minhas, Sandeep Banga, Abbas Ali, George Abela Source Type: research