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Source: Heart Rhythm

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Total 406 results found since Jan 2013.

Po-02-093 impact of ablation outcome on cognitive function in patients with atrial fibrillation
Emerging evidences suggest increased risk of all forms of dementia in patients with atrial fibrillation (AF) even in the absence of overt stroke. Cerebral hypoperfusion and the risk of cerebrovascular micro- and macro-embolism are plausible explanations for the predisposition for cognitive decline in AF.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Sanghamitra Mohanty, Angel Quintero Mayedo, Bryan MacDonald, Carola Gianni, VincenzoMirco La Fazia, Domenico G. Della Rocca, Prem Geeta Torlapati, Mohamed A. Bassiouny, G. Joseph Gallinghouse, John D. Burkhardt, Rodney P. Horton, Amin Al-Ahmad, Xiaodong Z Source Type: research

Po-01-047 evaluation of early removal of figure-of-eight suture post left atrial appendage closure device implantation
We report single center experience in outcomes in patients (pts) prior to and after implementation of a strategy of early (2 hr) removal of figure-of-eight (FO8) suture post LAAC device implantation.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Joseph M. Rogers, Karnik Patel, Jeffrey VanHook, Devender N. Akula Source Type: research

Po-01-121 microembolic signal evaluation during pulsed field ablation: preliminary results using an autonomous, robotically-assisted transcranial doppler
Transcranial Doppler (TCD) has been used to monitor the burden of cerebral microembolic signals (MESs) during cardiovascular procedures. Microemboli formation is considered a surrogate marker for stroke risk and has never been reported during pulsed field ablation (PFA).
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Domenico G. Della Rocca, Andrea Natale, Erwin Stroker, Juan Sieira, Anne-Marie Vanbinst, Antonia Ceccarelli, Luigi Pannone, Alvise Del Monte, Gezim Bala, Kaoru Tanaka, Alexandre Almorad, Sahar Mouram, Johan de Mey, Antonio Sorgente, Hubert Raeymaekers, Gi Source Type: research

Po-01-071 risk of stroke in patients with atrial fibrillation undergoing catheter ablation compared to medical therapy: a meta-analysis of randomized controlled trials
Atrial fibrillation (AF) is a major risk factor for stroke. Although catheter ablation is associated with higher chance of sinus rhythm maintenance compared to medical therapy, the extent to which successful catheter ablation reduces stroke risk remains unclear.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Mohammadali Habibi, Dan L. Musat, Advay G. Bhatt, Mark W. Preminger, Tina C. Sichrovsky, Suneet Mittal Source Type: research

Po-01-002 association of novel combined genetic polymorphisms with risk of thromboembolism in patients with atrial fibrillation
AF patients remain on oral anticoagulation (OAC) or left atrial appendage (LAA) closure is performed for thromboprophylaxis. However, clots on the closure device as well as stroke/transient ischemic attack (TIA) are observed to occur in some patients despite of being on blood thinners or after being off-OAC for a very brief period.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Sanghamitra Mohanty, Amitabh C. Pandey, Bryan MacDonald, Angel Quintero Mayedo, Carola Gianni, Prem Geeta Torlapati, Vincenzo Mirco La Fazia, Domenico G. Della Rocca, Mohamad Bassiouny, G. Joseph Gallinghouse, John D. Burkhardt, Rodney P. Horton, Amin Al- Source Type: research

Po-03-190 safety and outcomes of left atrial appendage occlusion in nonagenarians
As the human lifespan continues to lengthen, so too will the incidence of atrial fibrillation and the need for anticoagulation for stroke prevention. However, many of these patients that require anticoagulation are also at high risk of bleeding making left atrial appendage occlusion (LAAO) an attractive option. Studies on the procedural risks in the very elderly are limited and the safety of LAAO in nonagenarians is lacking.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Anis John Kadado, Alexandra Marenco, Jishu Motta, Khalid Sawalha, Kyle Gobeil, Michel Farah, Guy Rozen, Marshal Fox, Fadi M. Chalhoub Source Type: research

Po-03-164 feasibility of gadolinium contrast fluoroscopy to facilitate watchman flx implantation using intracardiac echocardiography
In patients with non-valvular atrial fibrillation, left atrial appendage closure (LAAC) is an alternative to oral anticoagulation for stroke-risk reduction. The standard imaging used during LAAC procedures is transesophageal echocardiography with iodinated contrast media. The recent worldwide supply chain shortage in April 2022 resulted in a global shortage of these contrast agents, limiting the ability to perform LAAC.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Dorothy Peng, Sarina A. van der Zee, Stephen Tang, Shephal K. Doshi Source Type: research

Po-01-043 challenging case of left atrial appendage occlusion after transcatheter mitral valve implantation with tendyne mitral valve system
Left atrial appendage occlusion (LAAO) is an alternative to reduce stroke risk in patients who are poor oral anticoagulant candidates. The Tendyne (Abbott Structural, Santa Clara, CA) transcatheter mitral valve implantation (TMVI) system consists of two self-expanding nitinol frames and a trileaflet porcine pericardial valve anchored to epicardial pad by a tether. The prominent atrial cuff of the device anchors the MV, and reduces paravalvular leak but can partially obstruct the LAA ostium making LAAO challenging
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Binaya Basyal, Michael Yang, Nebu Alexander, Vaani Garg, Sumbal Janjua, Irwin Feuerstein, Manish H. Shah Source Type: research

Po-03-135 left atrial appendage occlusion versus standard of care in patients with atrial fibrillation and a prior thrombo-embolic event despite oral anticoagulant therapy: a propensity score matched comparison
Patients with atrial fibrillation (AF) that suffer from ischemic stroke despite oral anticoagulant (OAC) therapy have a very high risk of recurrent stroke and better prevention strategies are needed. Left atrial appendage occlusion (LAAO) is a promising secondary prevention strategy that may provide mechanical protection. However, evidence showing effectiveness of LAAO in this population is scarce and the current international guidelines only consider LAAO in patients with a contra-indication for OAC.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Moniek Maarse, David Seiffge, Errol Aarnink, Nicolai Fierro, Patrizio Mazzone, Alessandro Beneduce, Alessio Gasperetti, Claudio Tondo, Radek Pracon, Marcin Demkow, Kamil Zielinski, Ole de Backer, Kasper Korsholm, Jens Erik Nielsen-Kudsk, Rodrigo Estevez-L Source Type: research

Po-03-134 long term outcomes following laao in a large medicare population
The Watchman left atrial appendage occlusion (LAAO) device was FDA approved for stroke risk reduction in patients with nonvalvular AF in 2015 based on data from randomized clinical trials. Long-term outcomes following LAAO outside clinical trials and small registries are largely unknown. Collecting these data was a condition of US market authorization.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Emily P. Zeitler, Boyang Bian, Dominic Allocco, Thomas Christen, Kristine Roy, David Cohen, Matthew R. Reynolds Source Type: research

Po-01-083 percutaneous closure of peri-device leak following left atrial appendage closure using an amplatzer duct occluder
Percutaneous left atrial appendage (LAA) closure has been recognised as an alternative therapy for stroke prevention in selected patients with non-valvular atrial fibrillation (AF) who have difficulties with long-term oral anticoagulation. Peri-device leaks (PDLs) are frequently diagnosed after LAA closure procedures, regardless of closure methods. PDL> 5mm is related with further embolic events. Nevertheless, management of severe PDL has been a challenging concern which requires multiple teams involved.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Rui Shi, John Foran, Ghada Mustafa, Omar H. Riad, Daniel Hunnybun, Vias Markides, Tom Wong Source Type: research

Po-03-133 both overuse and underuse of oral anticoagulation post-atrial fibrillation ablation in a large healthcare system
Guidelines recommend that decisions regarding oral anticoagulation (OAC) post ablation for atrial fibrillation (AF) should be based solely on the patient ’s stroke risk profile, regardless of the outcomes of the procedure. The adherence to this recommendation in clinical practice has not been examined.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Christopher Gasparis, Stefanos Zafeiropoulos, Jonas Leavitt, Dimitrios Varrias, Kristie Coleman, Elliot Wolf, Ari Zimmer, Rajat Goyal, Laurence M. Epstein, Stavros Mountantonakis Source Type: research

Po-01-087 a rare case of bi-atrial fdg-uptake: presenting as new onset atrial fibrillation
Isolated atrial myocarditis is rare, with presenting symptoms that are non-specific. Prior reports have suggested association with atrial arrythmias and increased risk of stroke due to atrial dysfunction. Fluorodeoxyglucose (FDG)-positron emission tomography (PET) CT scan is considered as a goal standard test for the diagnosis of myocarditis.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Adnan Ahmed, Danish Bawa, William C. Kellogg, Vasvi Singh, Rajesh Kabra, Naga Venkata K. Pothineni, Douglas Darden, Rakesh Gopinathannair, Dhanunjaya R. Lakkireddy Source Type: research

Po-01-108 elucidating the mechanism of atrial fibrillation in lamin a/c heart disease using human ipsc-derived atrial cardiomyocytes
Mutations in the LMNA gene, encoding the nuclear envelope proteins lamin A/C, cause cardiac arrhythmias, conduction disease, and dilated cardiomyopathy. Malignant arrhythmias such as atrial fibrillation (AF) and ventricular tachycardia are common and pose an increased risk of stroke and sudden cardiac death.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: William Janes, Asia Owais, Hanna Chen, Yining Chen, Michael Hill, Dawood Darbar, Srinath Yeshwant Source Type: research

Po-01-220 invasively diagnosed hfpef in af associated with functional remodelling of the left atrial appendage: implications for stroke risk
HFpEF commonly coexists with atrial fibrillation (AF). The influence of coexisting HFpEF on function of the left atrial appendage (LAA) and risk of stroke remains unknown.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Jonathan P. Ariyaratnam, Ricardo S. Mishima, Adrian D. Elliott, Prashanthan Sanders Source Type: research