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Source: American Heart Journal
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Total 491 results found since Jan 2013.
Transradial percutaneous coronary intervention in cardiogenic shock: A single-center experience
Conclusions: Transradial approach for PCI is possible and safe in up to two-thirds of patients with CS. Absence of radial pulse was the main factor preventing use of TRA. In multivariate analysis, TRA was associated with a lower risk of mortality.
Source: American Heart Journal - March 1, 2013 Category: Cardiology Authors: Oriol Rodriguez-Leor, Eduard Fernandez-Nofrerias, Xavier Carrillo, Josepa Mauri, Carolina Oliete, Maria del Carmen Rivas, Antoni Bayes-Genis Tags: Transradial Angiography and Intervention Source Type: research
Outcome and safety of same-day-discharge percutaneous coronary interventions with femoral access: A single-center experience
Conclusions: Same-day-discharge after uncomplicated PCI using femoral access is safe when patients are properly selected. The strategy may improve and benefit health costs in the future.
Source: American Heart Journal - January 28, 2013 Category: Cardiology Authors: Lisbeth Antonsen, Lisette Okkels Jensen, Per Thayssen Tags: Interventional Cardiology Source Type: research
Rate versus rhythm control for management of atrial fibrillation in clinical practice: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry
Background: All patients with atrial fibrillation (AF) require optimization of their ventricular rate. Factors leading to use of additional rhythm control in clinical practice have not been thoroughly defined.Methods: The ORBIT-AF registry enrolled patients with AF from a broad range of practice settings and collected data on rate versus rhythm control, as indicated by the treating physician. Multivariable logistic regression analysis was performed to identify factors associated with each strategy.Results: Of 10,061 patients enrolled, 6,859 (68%) were managed with rate only control versus 3,202 (32%) with rhythm control. P...
Source: American Heart Journal - February 22, 2013 Category: Cardiology Authors: Benjamin A. Steinberg, DaJuanicia N. Holmes, Michael D. Ezekowitz, Gregg C. Fonarow, Peter R. Kowey, Kenneth W. Mahaffey, Gerald Naccarelli, James Reiffel, Paul Chang, Eric D. Peterson, Jonathan P. Piccini Tags: Electrophysiology Source Type: research
The outcome of intra-aortic balloon pump support in acute myocardial infarction complicated by cardiogenic shock according to the type of revascularization: A comprehensive meta-analysis
Aims: Despite the recommendations of the current guidelines, scientific evidence continue to challenge the effectiveness of intra-aortic balloon pump (IABP) in acute myocardial infarction (AMI) complicated by cardiogenic shock. Moreover, 2 recent meta-analyses showed contrasting results. The aim of this study is to test the effect of IABP according to the type of therapeutic treatment of AMI: percutaneous coronary intervention (PCI), thrombolytic therapy (TT), or medical therapy without reperfusion. Articles published from January 1, 1986, to December 31, 2012, were collected and analyzed by meta-analysis.Methods and resul...
Source: American Heart Journal - March 27, 2013 Category: Cardiology Authors: Francesco Romeo, Maria Cristina Acconcia, Domenico Sergi, Alessia Romeo, Saverio Muscoli, Serafina Valente, Gian Franco Gensini, Flavia Chiarotti, Quintilio Caretta Tags: Curriculum in Cardiology Source Type: research
Treatment of functional mitral valve regurgitation with the permanent percutaneous transvenous mitral annuloplasty system: Results of the multicenter international Percutaneous Transvenous Mitral Annuloplasty System to Reduce Mitral Valve Regurgitation in Patients with Heart Failure trial
Conclusions: Overall, PTMA had mild impact on MR reduction, left ventricular remodeling, QOL, and exercise capacity. During follow-up, the risk/benefit ratio remained suboptimal.
Source: American Heart Journal - February 18, 2013 Category: Cardiology Authors: Jimmy MacHaalany, Luc Bilodeau, Rainer Hoffmann, Stefan Sack, Horst Sievert, Josef Kautzner, Christoph Hehrlein, Patrick Serruys, Mario Sénéchal, Pamela Douglas, Olivier F. Bertrand Tags: Valvular and Congenital Heart Disease Source Type: research
Atrial fibrillation among Medicare beneficiaries hospitalized with sepsis: Incidence and risk factors
Background: Newly diagnosed atrial fibrillation (AF) during severe sepsis is associated with increased risks of in-hospital stroke and mortality. However, the prevalence, incidence, and risk factors associated with AF during the sepsis syndromes are unclear.Methods: We identified patients with preexisting, newly diagnosed, or no AF in a nationally representative 5% sample of Medicare beneficiaries hospitalized with sepsis between 2004 and 2007. We identified multivariable-adjusted demographic and clinical characteristics associated with development of newly diagnosed AF during a sepsis hospitalization.Results: A total of 6...
Source: American Heart Journal - April 26, 2013 Category: Cardiology Authors: Allan J. Walkey, Melissa A. Greiner, Susan R. Heckbert, Paul N. Jensen, Jonathan P. Piccini, Moritz F. Sinner, Lesley H. Curtis, Emelia J. Benjamin Tags: Electrophysiology Source Type: research
Effect of atrioventricular and ventriculoventricular delay optimization on clinical and echocardiographic outcomes of patients treated with cardiac resynchronization therapy: A meta-analysis
Conclusion: The current literature suggests that routine AV and/or VV delay optimization has a neutral effect on clinical and echocardiographic outcomes based on pooled data from randomized and nonrandomized studies. Standardization of patient selection and optimization timing and method may help to further define the role of CRT device optimization.
Source: American Heart Journal - May 2, 2013 Category: Cardiology Authors: Dominique Auger, Ulas Hoke, Jeroen J. Bax, Eric Boersma, Victoria Delgado Tags: Curriculum in Cardiology Source Type: research
Sex differences in clinical outcomes in patients with stable angina and no obstructive coronary artery disease
Conclusions: Women with stable angina and nonobstructive CAD are 3 times more likely to experience a cardiac event within the first year of cardiac catheterization than men. A prospective trial to examine the impact of medical therapy on MACE in patients with nonobstructive CAD is warranted.
Source: American Heart Journal - May 1, 2013 Category: Cardiology Authors: Tara L. Sedlak, May Lee, Mona Izadnegahdar, C. Noel Bairey Merz, Min Gao, Karin H. Humphries Tags: Acute Ischemic Heart Disease Source Type: research
Evaluation of the dual peroxisome proliferator–activated receptor α/γ agonist aleglitazar to reduce cardiovascular events in patients with acute coronary syndrome and type 2 diabetes mellitus: Rationale and design of the AleCardio trial
Conclusions: AleCardio will establish whether the PPAR-α/γ agonist aleglitazar improves cardiovascular outcomes in patients with diabetes and high-risk coronary disease.
Source: American Heart Journal - July 29, 2013 Category: Cardiology Authors: A. Michael Lincoff, Jean-Claude Tardif, Bruce Neal, Stephen J. Nicholls, Lars Rydén, Gregory G. Schwartz, Klas Malmberg, John B. Buse, Robert R. Henry, Hans Wedel, Arlette Weichert, Ruth Cannata, Diederick E. Grobbee Tags: Trial Design Source Type: research
Effect of ticagrelor on the outcomes of patients with prior coronary artery bypass graft surgery: Insights from the PLATelet inhibition and patient outcomes (PLATO) trial
Conclusions: Prior-CABG patients presenting with acute coronary syndrome are a high-risk cohort for death and recurrent cardiovascular events but have a lower risk for major bleeding. Similar to the results in no-prior-CABG patients, ticagrelor was associated with a reduction in ischemic events without an increase in major bleeding.
Source: American Heart Journal - July 29, 2013 Category: Cardiology Authors: Emmanouil S. Brilakis, Claes Held, Bernhard Meier, Frank Cools, Marc J. Claeys, Jan H. Cornel, Philip Aylward, Basil S. Lewis, Douglas Weaver, Gunnar Brandrup-Wognsen, Susanna R. Stevens, Anders Himmelmann, Lars Wallentin, Stefan K. James Tags: Acute Ischemic Heart Disease Source Type: research
Change in enrollment patterns, patient selection, and clinical outcomes with the availability of drug-eluting stents in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial
Background: In the BARI 2D trial, patients with type 2 diabetes and stable coronary artery disease were randomized to prompt revascularization versus intensive medical therapy (IMT). This analysis sought to evaluate how the availability of drug-eluting stents (DESs) has changed practice and outcomes.Methods: In BARI 2D, 1,605 patients were in the percutaneous coronary intervention (PCI)–intended stratum. As DES became available midway through recruitment, we report clinical outcomes among patients who underwent IMT versus prompt PCI with bare-metal stents (BMSs) or DES up to 4 years.Results: In North America, after DES b...
Source: American Heart Journal - August 7, 2013 Category: Cardiology Authors: Binita Shah, Vankeepuram S. Srinivas, Jiang Lu, Maria M. Brooks, Eric R. Bates, Zoran S. Nedeljkovic, Jorge Escobedo, Gladwin S. Das, John J. Lopez, Frederick Feit Tags: Interventional Cardiology Source Type: research
High-sensitive cardiac troponin T and its relations to cardiovascular risk factors, morbidity, and mortality in elderly men
In this study, we investigated the associations of cardiac troponin T (cTnT) to cardiovascular (CV) disease and outcome in elderly men.Methods: Cardiac troponin T was measured using a high-sensitive assay in 940 men aged 71 years participating in the Uppsala Longitudinal Study of Adult Men. We assessed both the cross-sectional associations of cTnT to CV risk factors and morbidities including cancer and the longitudinal associations to outcomes over 10 years of follow-up.Results: Cardiac troponin T levels were measurable in 872 subjects (92.8%). In the cross-sectional analyses, cTnT was associated to CV risk factors (diabet...
Source: American Heart Journal - August 15, 2013 Category: Cardiology Authors: Kai M. Eggers, Jinan Al-Shakarchi, Lars Berglund, Bertil Lindahl, Agneta Siegbahn, Lars Wallentin, Björn Zethelius Tags: Coronary Artery Disease Source Type: research
Documentation of study medication dispensing in a prospective large randomized clinical trial: Experiences from the ARISTOTLE Trial
Conclusions: Rates of medication dispensing error were low and balanced between treatment groups. The initially reported dispensing error rate was the result of data recording and data management errors and not true medication dispensing errors. These analyses confirm the previously reported results of ARISTOTLE.
Source: American Heart Journal - August 19, 2013 Category: Cardiology Authors: John H. Alexander, Elliott Levy, Jack Lawrence, Michael Hanna, Anthony P. Waclawski, Junyuan Wang, Robert M. Califf, Lars Wallentin, Christopher B. Granger Tags: Electrophysiology Source Type: research
African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women's Health Initiative
Conclusion: African American race is significantly and inversely correlated with AF in postmenopausal women. The etiology of this association remains unclear and may be related to unidentified environmental differences. Larger studies are necessary to identify genetic determinants of AF in African Americans.
Source: American Heart Journal - August 9, 2013 Category: Cardiology Authors: Marco V. Perez, Thomas J. Hoffmann, Hua Tang, Timothy Thornton, Marcia L. Stefanick, Joseph C. Larson, Charles Kooperberg, Alex P. Reiner, Bette Caan, Carlos Iribarren, Neil Risch Tags: Electrophysiology Source Type: research
The need to know crude event rates in meta-analysis
Numerous reports have recently been aimed at comparing outcomes between on-pump and off-pump coronary artery bypass grafting (CABG). Among these, the meta-analysis by Palmerini et al compared percutaneous coronary intervention with CABG using a network design that included 1 patient group receiving percutaneous coronary intervention (n = 4,653) and 2 patient groups in whom CABG was performed either on-pump (n = 10,957) or off-pump (n = 7,119). The rate of stroke at 30 days was the main end point.
Source: American Heart Journal - July 26, 2013 Category: Cardiology Authors: Andrea Messori, Valeria Fadda, Dario Maratea, Sabrina Trippoli Tags: Letters to the Editor Source Type: research
