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Source: American Heart Journal
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Total 491 results found since Jan 2013.
Transcatheter closure of patent foramen ovale following cryptogenic stroke: An updated meta-analysis of randomized controlled trials
Conclusions Transcatheter closure is associated with a significant reduction in the risk of stroke compared to medical management at the expense of an increased risk of atrial arrhythmias.
Source: American Heart Journal - February 1, 2018 Category: Cardiology Source Type: research
An international cluster randomized quality-improvement trial to increase the adherence to evidence-based therapies for acute ischemic stroke and transient ischemic attack patients: Rationale and design of the BRIDGE STROKE trial
Publication date: Available online 30 September 2018Source: American Heart JournalAuthor(s): Maria Julia Machline-Carrion, Eliana Vieira Santucci, Lucas Petri Damiani, Cecilia Bahit, Germán Málaga, Octávio Marques Ponte-Neto, Sheila Cristina Ouriques Martins, Viviane Flumignan Zétola, Karina Normilio-Silva, Gabriel Rodrigues de Freitas, Alessandra Gorgulho, Antônio De Salles, Beatriz Gonzales Pacheco da Silva, Juliana Yamashita Santos, Isabella de Andrade Jesuíno, Priscila Regina Torres Bueno, Alexandre Biasi Cavalcanti, Hélio Penna Guimarães, Ying Xian, Janet Prvu BettgerAbstractBackgroundTranslating evidence into...
Source: American Heart Journal - October 4, 2018 Category: Cardiology Source Type: research
Ischemic stroke associated with left cardiac catheterization: The importance of modifiable and non-modifiable risk factors
Background: Stroke associated with left cardiac catheterization is a devastating complication, and its incidence has not changed over the decades.We investigated the incidence, in-hospital outcomes and the modifiable and non-modifiable risk factors for periprocedural ischemic stroke.Methods: Our retrospective cohort study included all patients experiencing periprocedural ischemic stroke among the 24,500 patients who underwent left cardiac catheterization between January 2003 and October 2010. The case group was compared with a group of control patients randomly selected among those who underwent the procedure during this p...
Source: American Heart Journal - January 21, 2013 Category: Cardiology Authors: Batric Popovic, Sylvain Carillo, Nelly Agrinier, Charles Christophe, Christine Selton-Suty, Yves Juillière, Etienne Aliot Tags: Interventional Cardiology Source Type: research
Apixaban versus warfarin in patients with atrial fibrillation according to prior warfarin use: Results from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial
Background: Patients with atrial fibrillation who are vitamin K antagonist (VKA)-naive may have a higher risk of thrombosis and/or bleeding than VKA-experienced patients.Methods and results: Using data from ARISTOTLE, we assessed baseline characteristics and the treatment effect of apixaban versus warfarin in the VKA-naive and VKA-experienced cohorts. We compared rates of study drug discontinuation and time-in-therapeutic range. Overall, 7,800 (43%) were VKA naive, and 10,401 were VKA experienced. At baseline, both groups were similar with respect to age and congestive heart failure, hypertension, age, diabetes, stroke sco...
Source: American Heart Journal - July 26, 2013 Category: Cardiology Authors: David A. Garcia, Lars Wallentin, Renato D. Lopes, Laine Thomas, John H. Alexander, Elaine M. Hylek, Jack Ansell, Michael Hanna, Fernando Lanas, Greg Flaker, Patrick Commerford, Denis Xavier, Dragos Vinereanu, Hongqiu Yang, Christopher B. Granger Tags: Electrophysiology Source Type: research
Rationale, design, and baseline characteristics of the Salt Substitute and Stroke Study (SSaSS) —A large-scale cluster randomized controlled trial
Publication date: June 2017 Source:American Heart Journal, Volume 188 Author(s): Bruce Neal, Maoyi Tian, Nicole Li, Paul Elliott, Lijing L. Yan, Darwin R. Labarthe, Liping Huang, Xuejun Yin, Zhixin Hao, Sandrine Stepien, Jingpu Shi, Xiangxian Feng, Jianxin Zhang, Yuhong Zhang, Ruijuan Zhang, Yangfeng Wu Lowering sodium intake with a reduced-sodium, added potassium salt substitute has been proved to lower blood pressure levels. Whether the same strategy will also reduce the risks of vascular outcomes is uncertain and controversial. The SSaSS has been designed to test whether sodium reduction achieved with a salt substitute...
Source: American Heart Journal - April 4, 2017 Category: Cardiology Source Type: research
Predictors of Oral Anticoagulant Non-prescription in Patients with Atrial Fibrillation and Elevated Stroke Risk
Conclusions In this registry of AF patients, older patients at elevated stroke and low bleeding risk were commonly treated with OAC. However, a variety of factors were associated with OAC non-prescription. Specifically, antiplatelet use was prevalent and associated with the highest likelihood of OAC non-prescription. Future studies are warranted to understand provider and patient rationale that may underlie observed associations with OAC non-prescription.
Source: American Heart Journal - March 11, 2018 Category: Cardiology Source Type: research
An international cluster-randomized quality improvement trial to increase the adherence to evidence-based therapies for acute ischemic stroke and transient ischemic attack patients: Rationale and design of the BRIDGE STROKE Trial
Publication date: January 2019Source: American Heart Journal, Volume 207Author(s): Maria Julia Machline-Carrion, Eliana Vieira Santucci, Lucas Petri Damiani, Cecilia Bahit, Germán Málaga, Octávio Marques Pontes-Neto, Sheila Cristina Ouriques Martins, Viviane Flumignan Zétola, Karina Normilio-Silva, Gabriel Rodrigues de Freitas, Alessandra Gorgulho, Antônio De Salles, Beatriz Gonzales Pacheco da Silva, Juliana Yamashita Santos, Isabella de Andrade Jesuíno, Priscila Regina Torres Bueno, Alexandre Biasi Cavalcanti, Hélio Penna Guimarães, Ying Xian, Janet Prvu BettgerBackgroundTranslating evidence into clinical practic...
Source: American Heart Journal - November 9, 2018 Category: Cardiology Source Type: research
Improving outcomes in patients with atrial fibrillation: Rationale and design of the Early treatment of Atrial fibrillation for Stroke prevention Trial
Conclusion: EAST will determine whether rhythm control therapy, when applied early after the initial diagnosis of AF, can prevent cardiovascular complications associated with AF.
Source: American Heart Journal - August 1, 2013 Category: Cardiology Authors: Paulus Kirchhof, Günter Breithardt, A. John Camm, Harry J. Crijns, Karl-Heinz Kuck, Panos Vardas, Karl Wegscheider Tags: Trial Design Source Type: research
Real-Time Physiologic Biomarker for Prediction of Atrial Fibrillation Recurrence, Stroke, and Mortality After Electrical Cardioversion − A Prospective observational study
Conclusions Patients with decreased LAAEV have an increased risk of AF recurrence, stroke and mortality following successful ECV. Real-time measurement of LAAEV by TEE may be a useful physiologic biomarker for individualizing treatment decisions in patients with AF.
Source: American Heart Journal - July 31, 2015 Category: Cardiology Source Type: research
Clinical decision support for stroke prevention in atrial fibrillation (CDS-AF): Rationale and design of a cluster randomized trial in the primary care setting
Conclusion The present study will investigate whether a clinical decision support system integrated in an EHR can increase adherence to guidelines regarding anticoagulant therapy in patients with AF. Trial registration www.clinicaltrials.gov registration number NCT02635685
Source: American Heart Journal - February 15, 2017 Category: Cardiology Source Type: research
Availability of patient decision aids for stroke prevention in atrial fibrillation: A systematic review
The objective of this review was to examine the existence and accessibility of, as well as select outcomes associated with, published, formally evaluated patient decision aids for stroke prevention in atrial fibrillation. Methods Six databases were searched from inception to March 2016 with a research librarian. Two authors independently reviewed potential articles, selected trials meeting inclusion criteria, and assessed outcome measures. Outcomes included: patient knowledge, involvement, choice, and decisional conflict. Results The search resulted in 666 articles; most were excluded for not examining stroke prevention in...
Source: American Heart Journal - June 3, 2017 Category: Cardiology Source Type: research
Four-year trends in oral anticoagulant use and declining rates of ischemic stroke among 194,030 atrial fibrillation patients drawn from a sample of 12 million people
ConclusionThere was a slight increase in the prevalence of AF between 2012 and 2015, while the overall use of antiplatelet agents decreased and that of OAC, particularly DOACs, increased. Over the same period, 1 year hospitalizations for ischemic stroke declined substantially, with a declining rate of hemorrhagic strokes.
Source: American Heart Journal - November 9, 2019 Category: Cardiology Source Type: research
