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Predictors of failure of early neurological improvement in early time window following endovascular thrombectomy: a multi-center study
ConclusionDiabetes mellitus history, pre-stroke mRS, longer last known well-to-puncture time, lack of modified thrombolysis in cerebral infarction = 3, and the number of mechanical thrombectomy passes are the predictors of FENI. Future large-scale studies are required to validate these findings.
Source: Frontiers in Neurology - September 14, 2023 Category: Neurology Source Type: research

Discharge prescription patterns for antiplatelet and statin therapy following carotid endarterectomy: an analysis of the vascular quality initiative
Conclusions Although statin use has substantially improved following CEA, more than half of individuals not on a statin preprocedure remained this way at discharge. In addition, DAPT at discharge was frequent, a quarter of whom were on SAPT preprocedure. Further efforts are needed to improve rates of new statin prescriptions, ensure appropriate APT intensity at discharge and determine how different discharge APT regimens impact outcomes.
Source: BMJ Open - July 25, 2023 Category: General Medicine Authors: Eppler, M., Singh, N., Ding, L., Magee, G., Garg, P. Tags: Open access, Cardiovascular medicine Source Type: research

Prosthesis Choice in Dialysis Patients Undergoing Mitral Valve Replacement
CONCLUSIONS: MVR in dialysis patients carries significant morbidity and increased mid-term mortality. Decreased life-expectancy should be considered in the tailoring of prosthesis choice to dialysis-dependent patients.PMID:37245789 | DOI:10.1016/j.athoracsur.2023.05.015
Source: The Annals of Thoracic Surgery - May 28, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Amit Iyengar Cindy Song Noah Weingarten David Rekhtman David A Herbst Max Shin Mark R Helmers Pavan Atluri Source Type: research

Diabetic Rodent Models for Chronic Stroke Studies
We present different pathophysiological features of diabetes in each rodent model along with the advantages and disadvantages of each model. Utilizing these models may aid the advancement of novel treatments and therapies to lower ischemic brain damage in patients of diabetes.PMID:36715951 | DOI:10.1007/978-1-0716-2926-0_30
Source: Molecular Medicine - January 30, 2023 Category: Molecular Biology Authors: Lea Julie Dalco Kunjan R Dave Source Type: research

Role of Intraoperative Neurophysiological Monitoring in Preventing Stroke after Cardiac Surgery
CONCLUSIONS: Permanent EEG change and diabetes were significant postoperative stroke predictors in cardiac surgeries. Furthermore, overall survival out to 10-years postoperatively was significantly higher in the group without intraoperative neurophysiological monitoring changes, emphasizing its important predictive role.PMID:36634835 | DOI:10.1016/j.athoracsur.2023.01.004
Source: The Annals of Thoracic Surgery - January 12, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Cara M Fleseriu Ibrahim Sultan James A Brown Amir Mina Jacob Frenchman Donald J Crammond Jeffrey Balzer Katherine M Anetakis Kathirvel Subramaniam Varun Shandal Forozan Navid Parthasarathy D Thirumala Source Type: research

Does bariatric surgery change the risk of acute ischemic stroke in patients with a history of transient ischemic attack? A nationwide analysis
CONCLUSIONS: After analyzing nationwide information, we conclude bariatric surgery helps decrease risk of AIS in patients with a history of TIA. However, this comparison is limited by the nature of the database; further studies are needed to better understand these results.PMID:36581552 | DOI:10.1016/j.soard.2022.11.013
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - December 29, 2022 Category: Surgery Authors: Roberto J Valera Cristina Botero-Fonnegra Vicente J Cogollo Mauricio Sarmiento-Cobos Lisandro Montorfano Carlos Rivera Liang Hong Emanuele Lo Menzo Samuel Szomstein Raul J Rosenthal Source Type: research

Characteristics and Outcomes of Candidemia in Patients with Durable Left Ventricular Assist Device Support
In conclusion, fungemia is a rare and severe complication in LVAD patients occurring early postimplant.
Source: ASAIO Journal - August 1, 2022 Category: Medical Devices Tags: Adult Circulatory Support Source Type: research

E-215 Single stent assisted coiling for wide neck bifurcation aneurysms: a multi-center core lab validated analysis demonstrating safety and efficacy
ConclusionThis study represents the first multi-center, core-lab validated data of the safety and efficacy of the L-stenting single stent technique for wide-neck bifurcation aneurysms. Further prospective studies in larger cohorts are necessary to compare the efficacy and safety of this treatment to other endovascular techniques for treatment of wide neck bifurcation aneurysms.Disclosures N. Siddiqui: None. R. De Leacy: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Siddiqui, N., De Leacy, R. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

P-032 Underlying intracranial atherosclerotic disease is associated with worse outcomes in acute large vessel occlusion undergoing endovascular therapy
ConclusionUnderlying ICAD is associated with a 2.7-fold increase in the odds of mortality and a 4.5-fold (1/0.22) increase in unfavorable functional outcome at 90 days in patients with LVO undergoing traditional MT. Further research is warranted to understand factors associated with poor outcomes and investigate alternative interventional approaches and medical management in this high-risk population.Disclosures S. Thind: None. R. Morsi: None. T. Karrison: None. E. Coleman: None. J. Brorson: None. C. McKoy: None. S. Mendelson: None. A. Mansour: None. S. Prabhakaran: None. T. Kass-Hout: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Thind, S., Morsi, R., Karrison, T., Coleman, E., Brorson, J., McKoy, C., Mendelson, S., Mansour, A., Prabhakaran, S., Kass-Hout, T. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

Direct Comparison of Outcomes After Transcatheter Aortic Valve Replacement in Veterans and Non-Veterans Using the Transcatheter Valve Therapy Registry
CONCLUSIONS: The affiliation between a VAMC and an academic medical center allowed for direct comparison between veterans and non-veterans undergoing TAVR by the same operators using the TVT registry. Despite significantly higher rates of comorbidities, veterans had equivalent outcomes compared with non-veterans. This may be in part due to the comprehensive care that veterans receive in the VAMC and this institution's integrated heart center team.PMID:35830359
Source: The Journal of Invasive Cardiology - July 13, 2022 Category: Cardiology Authors: Michael A Napolitano Timothy J Holleran Andrew D Sparks Jason R Morrissette Jennifer A DoCampo Federico E Mordini Michael D Greenberg Ramesh Mazhari Jonathan S Reiner Andrew D Choi Joseph Krepp Farzad Najam Elizabeth S Pocock Jared L Antevil Gregory D Tra Source Type: research

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