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Education: University of Wisconsin

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Total 21 results found since Jan 2013.

The perils of adult asthma: Those diagnosed later in life are '50% more likely to have a stroke or heart attack'
People diagnosed with asthma as children had the same risk of having a cardiovascular event as those without asthma, researchers from the University of Wisconsin found.
Source: the Mail online | Health - August 24, 2016 Category: Consumer Health News Source Type: news

Those diagnosed with adult asthma later in life '50% more likely to have stroke'
People diagnosed with asthma as children had the same risk of having a cardiovascular event as those without asthma, researchers from the University of Wisconsin found.
Source: the Mail online | Health - August 27, 2016 Category: Consumer Health News Source Type: news

Improved Outcomes in Asymptomatic Obstructive Sleep Apnea
This study enrolled 1522 randomly selected, employed research subjects and observed them for 2 decades. The goal of WSCS was to answer one aspect of a US Congressional mandate to determine the overall public burden of sleep d isorders. The WSCS had a surprising finding: mild OSA was seen in 17% of adults, and, most concerning, 6% of adults had moderate to severe OSA. The WSCS finding most relevant to the current USPSTF recommendation statement is that only 35% of WSCS participants with moderate OSA and 37% of participant s with severe OSA reported excessive daytime sleepiness, the cardinal daytime symptom of OSA. This sugg...
Source: JAMA Neurology - January 24, 2017 Category: Neurology Source Type: research

Early Pulmonary Vascular Disease in Young Adults Born Preterm.
CONCLUSION: Young adults born preterm demonstrate early pulmonary vascular disease, characterized by elevated pulmonary pressures, a stiffer pulmonary vascular bed, and right ventricular dysfunction, consistent with an increased risk of developing pulmonary hypertension. PMID: 29944842 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - June 26, 2018 Category: Respiratory Medicine Authors: Goss KN, Beshish AG, Barton GP, Haraldsdottir K, Levin TS, Tetri LH, Battiola TJ, Mulchrone AM, Pegelow DF, Palta M, Lamers LJ, Watson AM, Chesler NC, Eldridge MW Tags: Am J Respir Crit Care Med Source Type: research

Impaired Activity of Ryanodine Receptors Contributes to Calcium Mishandling in Cardiomyocytes of Metabolic Syndrome Rats
Conclusion Principal findings of this work are that abnormal Ca2+ transient amplitude, contractile dysfunction; and impaired relaxation of MetS cardiomyocytes underlies intrinsic dysfunctional RyR2 and SERCA pump. Abnormal activity of RyRs was evidenced by its decreased ability to bind [3H]-ryanodine. Although the MetS condition does not modify RyR2 protein expression, its phosphorylation at Ser2814 is decreased, which impairs its capacity for activation during ECC. The dysfunctional RyRs, together with a decreased activity of SERCA pump due to decreased Thr17-PLN phosphorylation suggest a downregulation of CaMKII in MetS...
Source: Frontiers in Physiology - April 29, 2019 Category: Physiology Source Type: research

Jawless fish take a bite out of the blood-brain barrier
(University of Wisconsin-Madison) A jawless parasitic fish could help lead the way to more effective treatments for multiple brain ailments, including cancer, trauma and stroke. A team of biomedical engineers and clinician-scientists at the University of Wisconsin-Madison and the University of Texas at Austin borrowed molecules from the immune system of the parasitic sea lamprey to deliver anti-cancer drugs directly to brain tumors.
Source: EurekAlert! - Cancer - May 15, 2019 Category: Cancer & Oncology Source Type: news