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Combining Human Umbilical Cord Blood Cells With Erythropoietin Enhances Angiogenesis/Neurogenesis and Behavioral Recovery After Stroke
In conclusion, our results suggest that hUCBC infusion in combination with EPO administration demonstrates therapeutic efficacy in the treatment of stroke-induced injury by promoting neurogenesis and angiogenesis. Further research that delineates the therapeutic mechanism of systemically administered hUCBC and EPO is required. Ethics Statement All experimental procedures involving animals were performed in accordance with the Guide for the Care and Use of Laboratory Animals as adopted and promulgated by the U. S. National Institutes of Health and were approved by CHA University Institutional Animal Care & Use Com...
Source: Frontiers in Neurology - April 9, 2019 Category: Neurology Source Type: research

Saving brain cells after stroke by halting immune response
A new study in animals shows that using a compound to block the body's immune response greatly reduces disability after a stroke.The study by scientists from the University of Wisconsin School of Medicine and Public Health also showed that particular immune cells - CD4+ T-cells produce a mediator, called interleukin (IL) -21 that can cause further damage in stroke tissue. Moreover, normal mice, ordinarily killed or disabled by an ischemic stroke, were given a shot of a compound that blocks the action of IL-21.
Source: Health News from Medical News Today - March 18, 2014 Category: Consumer Health News Tags: Stroke Source Type: news

Halting immune response could save brain cells after stroke
(University of Wisconsin-Madison) A new study in animals shows that using a compound to block the body's immune response greatly reduces disability after a stroke.
Source: EurekAlert! - Medicine and Health - March 13, 2014 Category: Global & Universal Source Type: news