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Increased Glucose Variability Is Associated With Major Adverse Events After Coronary Artery Bypass
ConclusionsIncreased 24-hour, but not 12-hour, postoperative GV following CABG is a predictor of poor outcomes. Preoperative HbA1c is not associated with MAEs after adjusting for postoperative mean glucose and GV.Graphical abstract
Source: The Annals of Thoracic Surgery - August 7, 2019 Category: Cardiovascular & Thoracic Surgery Source Type: research

Increased Glucose Variability Is Associated With Major Adverse Events After Coronary Artery Bypass.
CONCLUSIONS: Increased 24-hour, but not 12-hour, postoperative GV following CABG is a predictor of poor outcomes. Preoperative HbA1c is not associated with MAEs after adjusting for postoperative mean glucose and GV. PMID: 31400320 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - August 6, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Clement KC, Suarez-Pierre A, Sebestyen K, Alejo D, DiNatale J, Whitman GJR, Matthew TL, Lawton JS Tags: Ann Thorac Surg Source Type: research

Effects and outcomes of cardiac surgery in patients with cardiometabolic syndrome
ConclusionsPatients with CMS were more likely to present with increased comorbidities. Patients with CMS undergoing CABG were at risk for worse short ‐term secondary postoperative outcomes and reduced long‐term survival. The data supports the need for further investigation for risk reduction surrounding operative revascularization.
Source: Journal of Cardiac Surgery - February 17, 2020 Category: Cardiovascular & Thoracic Surgery Authors: David Zapata, Michael Halkos, Jose Binongo, John Puskas, Robert Guyton, Omar Lattouf Tags: ORIGINAL ARTICLE Source Type: research

Ten-year all-cause death following percutaneous or surgical revascularization in patients with prior cerebrovascular disease: insights from the SYNTAX Extended Survival study
ConclusionPrior CEVD was associated with a significantly increased risk of 10  year all-cause death which was similar in patients treated with PCI or CABG. These results do not support preferential referral for PCI rather than CABG in patients with prior CEVD.Trial registration: SYNTAX: ClinicalTrials.gov reference: NCT00114972. SYNTAX Extended Survival: ClinicalTrials.gov reference: NCT03417050.Graphic abstract
Source: Clinical Research in Cardiology - January 30, 2021 Category: Cardiology Source Type: research

Short- and Long-term cardiovascular outcomes in insulin-treated versus non-insulin-treated diabetes mellitus patients after percutaneous coronary intervention: a systematic review and meta-analysis
CONCLUSION: Despite a tremendous technical success rate of multi-vessel stenting, people living with diabetes who were being treated with insulin had higher long-term, and short-term mortality rates, MI, TLR, TVR, and stroke compared to people living with diabetes who were being treated with means other than insulin and are more prone to detrimental cardiovascular outcomes.PMID:34906538 | DOI:10.1016/j.ihj.2021.12.004
Source: Indian Heart J - December 15, 2021 Category: Cardiology Authors: Wardah Hassan Javeria Saquib Mahima Khatri Syeda Kanza Kazmi Sohny Kotak Hani Hassan Jawad Ahmed Source Type: research

Glutamate infusion reduces myocardial dysfunction after coronary artery bypass grafting according to NT-proBNP: summary of two randomized controlled trials (GLUTAMICS I-II)
CONCLUSIONS: Infusion of glutamate reduced postoperative rise in NT-proBNP after CABG in medium to high-risk patients. A significantly blunted effect was observed only in insulin-treated diabetes patients.CLINICAL TRIAL REGISTRATION: NCT02592824, https://clinicaltrials.gov/ct2/show/NCT02592824.PMID:37657522 | DOI:10.1016/j.ajcnut.2023.08.012
Source: The American Journal of Clinical Nutrition - September 1, 2023 Category: Nutrition Authors: Jonas Holm Farkas Vanky Rolf Svedjeholm Source Type: research

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