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Total 8 results found since Jan 2013.

The potential therapeutic effect of phosphodiesterase 5 inhibitors in the acute ischemic stroke (AIS)
In conclusion, PDE5 inhibitors may have potential roles in the management of AIS through modulation of CBF, cAMP/cGMP/NO pathway, neuroinflammation, and inflammatory signaling pathways. Preclinical and clinical studies are recommended in this regard.PMID:37395897 | DOI:10.1007/s11010-023-04793-1
Source: Molecular and Cellular Biochemistry - July 3, 2023 Category: Biochemistry Authors: Raed AlRuwaili Hayder M Al-Kuraishy Mubarak Alruwaili Amira Karam Khalifa Athanasios Alexiou Marios Papadakis Hebatallah M Saad Gaber El-Saber Batiha Source Type: research

New shot for men and women
Today I want to tell you about a quick, painless procedure that will put the spontaneity back into your sex life. And you don’t have to take a pill and then wait 30 minutes or more… I’m talking about platelet-rich plasma, or PRP for short. I’ve used PRP in my patients to heal sports injuries, aching joints and surgical wounds. It’s better than a facelift to smooth fine lines and wrinkles. But PRP also works if you’re having trouble in the bedroom. More than a third of men suffer from sexual dysfunction. And 40% of women do too. I’m talking about everything from erectile dysfunctio...
Source: Al Sears, MD Natural Remedies - October 5, 2017 Category: Complementary Medicine Authors: Al Sears Tags: Anti-Aging Men's Health Women's Health Source Type: news

Upfront combination therapy in the treatment of scleroderma-associated pulmonary arterial hypertension: Results of an open label trial
Conclusions: Upfront combination therapy resulted in significant changes in hemodynamics, RV structure and function, and RV-pulmonary vascular coupling as well as functional status at 36 weeks of therapy. When compared to previous clinical trials, these data suggest initial combination therapy is very effective for SSc-PAH.
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Hassoun, P., Zamanian, R., Damico, R., Khair, R., Kolb, T., Tedford, R., Hulm, O., Pisanello, C., Sato, T., Corona-Villalobos, C., Zimmerman, S., Gashouta, M., Minai, O., Torres, F., Chin, K., Girgis, R., Mathai, S. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

Ambrisentan and Tadalafil Upfront Combination Therapy in Scleroderma-Associated PAH.
CONCLUSIONS: Upfront ambrisentan and tadalafil therapy significantly improved hemodynamics, RV structure and function, and functional status in treatment naïve SSc-PAH patients and may represent a very effective therapy for this patient population. In addition, we have identified novel hemodynamic and imaging biomarkers that could have potential value in future clinical trial trials. Clinical trial registration available at www.clinicaltrials.gov, ID NCT01042158. PMID: 26360334 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - September 11, 2015 Category: Respiratory Medicine Authors: Hassoun PM, Zamanian RT, Damico R, Lechtzin N, Khair R, Kolb TM, Tedford RJ, Hulme OL, Housten T, Pisanello C, Sato T, Pullins EH, Corona-Villalobos CP, Zimmerman SL, Gashouta MA, Minai OA, Torres F, Girgis RE, Chin K, Mathai SC Tags: Am J Respir Crit Care Med Source Type: research

Re: Regional Cerebral Blood Flow following Single-Dose and Continuous-Dose Tadalafil after Stroke
M. Lorberboym, E. Makhline and Y. Lampl
Source: The Journal of Urology - January 20, 2015 Category: Urology & Nephrology Authors: Allen D. Seftel Tags: Urological Survey Source Type: research

A Cross Between Ginger and a Carrot
I woke up with the sunlight … and birds singing so loudly I thought they were in the room with me. I walked out of my cottage to a warm breeze, and sat down to a delicious breakfast: fresh fruit, banana pancakes and a tall glass of jackfruit juice. I made my way to my friends Westi and Lelir’s house, where he greeted me with a long “pick and hoe” garden cultivating tool. Westi said, “Ready?” smiling, holding out the long handle towards me. We walked up the steep hill behind his home to his private herb garden. I wondered what we might harvest today. He stopped in front of a row of very tall plants and smiled, ...
Source: Al Sears, MD Natural Remedies - October 13, 2014 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Anti-Aging Hormone Health Source Type: news

Regional cerebral blood flow following single‐dose and continuous‐dose tadalafil after stroke
ConclusionTadalafil administration after cerebral stroke may be associated with diminished blood flow to areas adjacent to the stroke. The alterations in perfusion suggest a need for caution in prescribing tadalafil to patients with a history of stroke, especially with continuous administration that may impose constant stress on the cerebral circulation.
Source: Acta Neurologica Scandinavica - September 10, 2014 Category: Neurology Authors: M. Lorberboym, E. Makhline, Y. Lampl Tags: Original Article Source Type: research