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Drug: Sevoflurane

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Total 84 results found since Jan 2013.

PHLDA1 promotes sevoflurane-induced pyroptosis of neuronal cells in developing rats through TRAF6-mediated activation of Rac1
In conclusion, loss of PHLDA1 protected against sevoflurane-induced pyroptosis in developing rats through inhibition of TRAF6-mediated activation of Rac1.PMID:36155068 | DOI:10.1016/j.neuro.2022.09.007
Source: Neurotoxicology - September 26, 2022 Category: Neurology Authors: Lijuan Shu Chunfu Du Source Type: research

Sevoflurane alleviates myocardial ischemia/reperfusion injury via actitation of heat shock protein-70 in patients undergoing double valve replacement surgery
This study investigated the cardioprotective effect(s) of sevoflurane in rheumatic heart disease patients undergoing double valve replacement surgery (DVRS) under cardiopulmonary bypass (CPB) and its potential mechanisms (ChiCTR2100051220 on http://www.ChiCTR.org.cn). Forty-six patients were randomly assigned to undergo propofol or sevoflurane anesthesia during surgery. The levels of myocardial injury markers, inflammatory cytokines, heat shock protein-70 (HSP70), and superoxide dismutase (SOD) activity were measured from blood samples. Mean arterial pressure, cardiac index, and stroke volume index were significantly highe...
Source: American Journal of Translational Research - September 15, 2022 Category: Research Authors: Yue Shan Kai Xie Qifu Zhou Rui He Zhonghua Chen Weizhong Feng Source Type: research