PHLDA1 promotes sevoflurane-induced pyroptosis of neuronal cells in developing rats through TRAF6-mediated activation of Rac1

In conclusion, loss of PHLDA1 protected against sevoflurane-induced pyroptosis in developing rats through inhibition of TRAF6-mediated activation of Rac1.PMID:36155068 | DOI:10.1016/j.neuro.2022.09.007

Source: Neurotoxicology - September 26, 2022 Category: Neurology Authors: Lijuan Shu Chunfu Du Source Type: research