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Total 22 results found since Jan 2013.

A case of drug-induced metabolic encephalopathy presenting to the stroke unit (P3.282)
Conclusions:This highly unusual case of acute drug-induced encephalopathy with profound thyrotoxicosis presents as a stroke-mimic. Cannabinoids are more typically associated with reversible cerebral vasoconstriction syndrome which was not present here illustrating an important point that there is much less certainty about the actual content of recreational drugs with the advent of ‘legal-highs’. We speculate as to whether his neurological presentation and thyrotoxicosis are related to his drug use or he has in fact two separate insults to his brain.Study Supported by: Not applicableDisclosure: Dr. Maduakor has ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Maduakor, C., Vasan, S., Khan, U. Tags: Cerebrovascular Disease Case Reports II Source Type: research

New recommendations aim to improve safety of pain-relieving spinal steroid injections
More and more people are seeking injections of anti-inflammatory steroid medications for back and neck pain. In 2011, the last year for which complete information is available, doctors pushed the plunger on 2.3 million steroid injections into the spine — and that’s just among people covered by Medicare. These injections deliver drugs that mimic the effects of two hormones, cortisone and hydrocortisone, to reduce inflammation and help relieve pain. When they work — they don’t always — such injections can bring profound relief. “If you are in severe pain with a ruptured spinal disc and you get a stero...
Source: New Harvard Health Information - May 7, 2015 Category: Consumer Health News Authors: Daniel Pendick Tags: Back Pain Drugs and Supplements anti-inflammatory steroid medications spinal injections spine steroid injections Source Type: news

Urticarial allergic reaction to alteplase: A case report (P6.243)
CONCLUSIONS: Physicians treating acute ischemic stroke with alteplase should be aware of this uncommon but potentially dangerous complication in the spectrum of anaphylactic reactions.Disclosure: Dr. Papolin has nothing to disclose. Dr. Mendes has nothing to disclose. Dr. Lange has nothing to disclose. Dr. Germiniani has nothing to disclose. Dr. Harger has nothing to disclose. Dr. Zetola has nothing to disclose. Dr. Chamma has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Papolin, L., Mendes, D., Lange, M., Germiniani, F., Harger, R., Zetola, V., Chamma, J. Tags: Cerebrovascular Disease and Interventional Neurology: Thrombolysis Complications Source Type: research

Ischemia/reperfusion-induced upregulation of TIGAR in brain is mediated by SP1 and modulated by ROS and hormones involved in glucose metabolism
Publication date: Available online 4 November 2014 Source:Neurochemistry International Author(s): Meiling Sun , Mei Li , Qiao Huang , Feng Han , Jin-hua Gu , Jiaming Xie , Rong Han , Zheng-Hong Qin , Zhipeng Zhou We previously found that TIGAR (TP53-induced glycolysis and apoptosis regulator) was upregulated in response to ischemia/reperfusion insult in a TP53-independent manner. The present study sought to investigate the regulatory mechanisms of TIGAR upregulation in animal and cellular models of stroke. The animal and cellular models of ischemia/reperfusion were produced by transient middle cerebral artery occlusion a...
Source: Neurochemistry International - November 4, 2014 Category: Neuroscience Source Type: research

Presentation of atrial fibrillation following oral dexamethasone treatment in a NF2 patient
We describe a case of A-fib in a 50year-old female patient with neurofibromatosis type 2 (NF-2), who was prescribed dexamethasone for post-radiation tumor edema.
Source: American Journal of Otolaryngology - October 12, 2014 Category: Endocrinology Source Type: research

Cerebral Vasoconstriction Triggered By Sympathomimetic Drugs During Intra-atrerial Chemotherapy
In this report, we highlight the potential risk of reversible cerebral vasoconstriction in children administered vasoactive drugs and discuss its relevance during treatment of retinoblastoma by intraarterial chemotherapy.
Source: Pediatric Neurology - January 21, 2013 Category: Neurology Authors: Todd Abruzzo, Mario Patino, James Leach, Ralph Rahme, James Geller Tags: Case Reports Source Type: research