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Total 22 results found since Jan 2013.
A case of drug-induced metabolic encephalopathy presenting to the stroke unit (P3.282)
Conclusions:This highly unusual case of acute drug-induced encephalopathy with profound thyrotoxicosis presents as a stroke-mimic. Cannabinoids are more typically associated with reversible cerebral vasoconstriction syndrome which was not present here illustrating an important point that there is much less certainty about the actual content of recreational drugs with the advent of ‘legal-highs’. We speculate as to whether his neurological presentation and thyrotoxicosis are related to his drug use or he has in fact two separate insults to his brain.Study Supported by: Not applicableDisclosure: Dr. Maduakor has ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Maduakor, C., Vasan, S., Khan, U. Tags: Cerebrovascular Disease Case Reports II Source Type: research
A case of Lemierre's syndrome causing panhypopituitarism, cavernous sinus thrombosis, ischaemic stroke and pulmonary embolism
We present the case of a previously well 19-year-old man, who presented acutely unwell with meningitis and sepsis. Fusobacterium necrophorum was isolated from peripheral blood cultures and identified on cerebrospinal fluid with 16S rDNA Polymerase Chain Reaction (PCR). Imaging demonstrated internal jugular vein thrombosis with subsequent cavernous venous sinus thrombosis. Pituitary function tests were suggestive of panhypopituitarism. The patient was diagnosed with Lemierre's syndrome complicated by meningitis, cavernous sinus thrombosis, base of skull osteomyelitis, ischaemic stroke and panhypopituitarism. He was treated ...
Source: Journal of the Royal College of Physicians of Edinburgh - September 7, 2023 Category: General Medicine Authors: Charlotte J Dewdney Joseph J Anderson Simon Dewar Fergus Doubal Frederick R Burgess Deepak Subedi Marcus J Lyall Source Type: research
Urticarial allergic reaction to alteplase: A case report (P6.243)
CONCLUSIONS: Physicians treating acute ischemic stroke with alteplase should be aware of this uncommon but potentially dangerous complication in the spectrum of anaphylactic reactions.Disclosure: Dr. Papolin has nothing to disclose. Dr. Mendes has nothing to disclose. Dr. Lange has nothing to disclose. Dr. Germiniani has nothing to disclose. Dr. Harger has nothing to disclose. Dr. Zetola has nothing to disclose. Dr. Chamma has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Papolin, L., Mendes, D., Lange, M., Germiniani, F., Harger, R., Zetola, V., Chamma, J. Tags: Cerebrovascular Disease and Interventional Neurology: Thrombolysis Complications Source Type: research
The pivotal role of micro-environmental cells in a human blood –brain barrier in vitro model of cerebral ischemia: functional and transcriptomic analysis
ConclusionsThe co-cultivation with micro-environmental cells is necessary to achieve a functional breakdown of the BBB in the cerebral ischemia model within an in vivo relevant time window. Comprehensive studies by qPCR revealed that distinct expression clusters of barrier markers exist and that these are regulated by different treatments (even by growth medium change) indicating that controls for single cell culture manipulation steps are crucial to understand the observed effects properly.
Source: Fluids and Barriers of the CNS - March 4, 2020 Category: Neuroscience Source Type: research
Cerebral Vasoconstriction Triggered By Sympathomimetic Drugs During Intra-atrerial Chemotherapy
In this report, we highlight the potential risk of reversible cerebral vasoconstriction in children administered vasoactive drugs and discuss its relevance during treatment of retinoblastoma by intraarterial chemotherapy.
Source: Pediatric Neurology - January 21, 2013 Category: Neurology Authors: Todd Abruzzo, Mario Patino, James Leach, Ralph Rahme, James Geller Tags: Case Reports Source Type: research
