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MR ASAP: No Benefit of Prehospital Nitroglycerin in Stroke MR ASAP: No Benefit of Prehospital Nitroglycerin in Stroke
Giving transdermal nitroglycerin to stroke patients in the ambulance within 3 hours of symptom onset was not shown to be of any benefit in the MR ASAP trial, which was stopped early owing to futility.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - September 7, 2021 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Regional Differences in Early BP Management After Acute Ischemic Stroke in the ENCHANTED International Randomized Controlled Trials
Conclusion: Regional variations in early BP management in acute stroke translated into differences in early BP control parameters.
Source: Frontiers in Neurology - August 27, 2021 Category: Neurology Source Type: research

Nitroglycerin is Not Associated with Improved Cerebral Perfusion in Acute Ischemic Stroke.
PMID: 32799944 [PubMed - as supplied by publisher]
Source: The Canadian Journal of Neurological Sciences - August 16, 2020 Category: Neurology Authors: Kate M, Gioia L, Asdaghi N, Jeerakathil T, Shuaib A, Buck B, Emery D, Beaulieu C, Butcher K Tags: Can J Neurol Sci Source Type: research

International Stroke Conference: Nitroglycerin Patches Applied En Route to the Hospital Fail to Improve Stroke Outcomes
No abstract available
Source: Neurology Today - March 7, 2019 Category: Neurology Tags: At the Meetings Source Type: research

Collateral Blood Flow Availability in Acute Ischemic Stroke: A Case Report (P4.360)
Conclusion: This case supports earlier autopsy specimen dissections indicating most borderzone collaterals linking to adjacent vascular territories are too small to generate the immediate flow needed to spare tissue proximal to a middle cerebral stem occlusion. Assuming acute vasodilation is possible for these vessels, the acute use of vasodilators such as nitroglycerin or hydralazine and calcium-channel blockers like Nimodipine could provide an area for future study.Disclosure: Dr. Rostanski has nothing to disclose. Dr. Lavine has nothing to disclose. Dr. Mohr has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Rostanski, S., Lavine, S., Mohr, J. Tags: Cerebrovascular Case Reports Source Type: research

Anti-Vascular endothelial growth factor therapy impairs endothelial function of retinal microcirculation in colon cancer patients – an observational study
Conclusions Bevacizumab acutely impairs microvascular function independent of blood pressure changes. Imaging of the retinal microcirculation seems a valuable tool for monitoring pharmacodynamic effects of bevacizumab. Trial registration NCT ID: NCT00740168
Source: Experimental and Translational Stroke Medicine - May 13, 2013 Category: Neurology Source Type: research