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Total 41 results found since Jan 2013.

Scientific Landscape of Oxidative Stress in Stroke: From a Bibliometric Analysis to an in-Depth Review
Neurochem Res. 2023 Jul 28. doi: 10.1007/s11064-023-03999-5. Online ahead of print.ABSTRACTStroke is an acute cerebrovascular disease resulting from either obstruction or rupture of a blood vessel in the brain. Oxidative stress (OS), referred to a status where cellular oxidative capacities overwhelm antioxidative defenses, is involved in the pathophysiology of stroke. The bibliometric analysis and in-depth review aim to depict the research trend of OS in stroke. Relevant scientific publications were acquired from the Web of Science Core Collection database. Scientific landscape of OS in stroke was illustrated by general qu...
Source: Neurochemical Research - July 28, 2023 Category: Neuroscience Authors: Minqi Zhou Jiayu Xin Jinyu Chen Caiyun Sun Bingyue Huo Wenting Zhang Xiangqian Liu Source Type: research

Supporting Post-Stroke Language and Cognition with Pharmacotherapy: Tools for Each Phase of Care
AbstractPurpose of ReviewThere is enormous enthusiasm for the possibility of pharmacotherapies to treat language deficits that can arise after stroke. Speech language therapy remains the most frequently utilized and most strongly evidenced treatment, but the numerous barriers to patients receiving the therapy necessary to recover have motivated the creation of a relatively modest, yet highly cited, body of evidence to support the use of pharmacotherapy to treat post-stroke aphasia directly or to augment traditional post-stroke aphasia treatment. In this review, we survey the use of pharmacotherapy to preserve and support l...
Source: Current Neurology and Neuroscience Reports - June 5, 2023 Category: Neuroscience Source Type: research

Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines
AbstractPurpose of ReviewStroke is a leading cause of death and disability worldwide. The annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the United States, of which 87% are ischemic in nature. In addition to the management of modifiable high-risk factors to reduce the risk of recurrent stroke, antithrombotic agents (antiplatelets and anticoagulants) play an important role in secondary stroke prevention. This review will discuss the published literature on the use of antiplatelets and anticoagulants in secondary prevention of acute ischemic stroke and transient ischemic attack (TIA), ...
Source: Current Neurology and Neuroscience Reports - April 11, 2023 Category: Neuroscience Source Type: research

Getting the guts to expand stroke treatment: The potential for microbiome targeted therapies
CONCLUSION: Recent research has illuminated the vital role of the GBA in propagating poor clinical outcomes, such as hemorrhagic transformation, following ischemic stroke. Considering this detrimental consequence of stroke, and the apparent role of the GBA role, future therapeutics should aim to mitigate this peripheral contribution to stroke complications.PMID:36217699 | DOI:10.1111/cns.13988
Source: CNS Neuroscience and Therapeutics - October 11, 2022 Category: Neuroscience Authors: Molly Monsour Davide M Croci Siviero Agazzi Cesario V Borlongan Source Type: research

Implementation of an Advanced Practice Registered Nurse–Led Clinic to Improve Follow-up Care for Post–Ischemic Stroke Patients
CONCLUSION: An APRN-led clinic can improve follow-up care and may reduce unplanned 30-day readmissions for post–ischemic stroke patients. Further work is needed to determine the impact of alternative approaches such as telehealth.
Source: Journal of Neuroscience Nursing - September 10, 2022 Category: Neuroscience Tags: Clinical Nursing Focus Source Type: research

Research trends of the neuroimaging in aphasia: A bibliometric analysis and visualization analysis from 2004 to 2021
ConclusionThe results of this bibliometric study revealed the following three research hotspots in the neuroimaging of aphasia: clarifying the connotation of the most recognized language processing model, the dual-stream model, exploring the injury mechanism based on the dual-stream model and the recovery mechanism involving the left and right hemispheres of PSA, and determining the diagnostic criteria for PPA variants. A major research trend is to combine new neuroimaging technology, such as PET tracer technology, to realize the visual presentation of disease-specific proteins to improve the pathological diagnostic criter...
Source: Frontiers in Human Neuroscience - July 15, 2022 Category: Neuroscience Source Type: research

Challenges and Opportunities in Stroke Nursing Research: Global Views From a Panel of Nurse Researchers
This article reflects panel insights on challenges and opportunities for nurse-led stroke research. DISCUSSION: The research challenges discussed include nursing independence, the processes of informed consent and randomization process, obtaining adequate independent funding, recruiting research subjects, and working with vulnerable groups. The major opportunities to leverage and improve stroke nursing research include facilitating the nurse investigator role, information digitalization, improving health literacy, and collaboration between nurse researchers. SUMMARY: We are living in a volatile, uncertain, complex, and amb...
Source: Journal of Neuroscience Nursing - May 13, 2022 Category: Neuroscience Tags: Articles Source Type: research

Gamified Neurorehabilitation Strategies for Post-stroke Motor Recovery: Challenges and Advantages
AbstractPurpose of ReviewStroke is the leading cause of permanent motor disability in the United States (US), but there has been little progress in developing novel, effective strategies for treating post-stroke motor deficits. The past decade has seen the rapid development of many promising, gamified neurorehabilitation technologies; however, clinical adoption remains limited. The purpose of this review is to evaluate the recent literature surrounding the adoption and use of gamification in neurorehabilitation after stroke.Recent FindingsGamification of neurorehabilitation protocols is both feasible and effective. Deploym...
Source: Current Neurology and Neuroscience Reports - March 12, 2022 Category: Neuroscience Source Type: research

Stroke-Specific Refinements to Naylor's Transitional Care Model to Address the Storm of Uncertainty and Unmet Survivor and Caregiver Needs
CONCLUSION: Unmet needs identified by SSs and CGs were used to extend NTCM specific to the stroke population and to develop the Recommendations and Exemplars for Stroke Specific Comprehensive Transitional Care Delivery (see Supplementary Digital Content, available at http://links.lww.com/JNN/A385). Researchers and practitioners can use the findings to develop and deliver more comprehensive TC to SSs and CGs.
Source: Journal of Neuroscience Nursing - January 15, 2022 Category: Neuroscience Tags: Articles Source Type: research

Ischemic Stroke Risk Among Adult Brain Tumor Survivors: Evidence to Guide Practice
CONCLUSION: Nurses play a key role in the assessment, prevention, and identifying individuals who are at risk of AIS during brain tumor survivorship. Engaging patients and their caregivers on minimizing their risks of AIS is crucial in the outpatient setting. Annual surveillance visits that include intracranial artery imaging should be used to identify individuals considered most at risk for developing AIS symptoms.
Source: Journal of Neuroscience Nursing - September 9, 2021 Category: Neuroscience Tags: Clinical Nursing Focus Source Type: research

The 100 most-cited articles about the role of neurovascular unit in stroke 2001-2020: A bibliometric analysis
CONCLUSION: There has been growing attention and efforts made in the field of stroke and NVU. The merit of the above findings may help to shape the research policy in ischemic stroke both at the country and institutional level.PMID:33764687 | DOI:10.1111/cns.13636
Source: CNS Neuroscience and Therapeutics - March 25, 2021 Category: Neuroscience Authors: Lv Xie Bingwei Lu Yezhi Ma Jiemin Yin Xiaozhu Zhai Chen Chen Wanqing Xie Yueman Zhang Li Zheng Peiying Li Source Type: research