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Association between Coronary Artery Spasm and the risk of incident Diabetes: A Nationwide population-based Cohort Study
Conclusion: CAS is a risk factor for incident diabetes regardless of sex. However, females aged <50 years have a more apparent risk for CAS-related diabetes than old females, which is not observed in males. The median time of 2.9 years to incident diabetes warrants close follow-up.PMID:34104095 | PMC:PMC8176166 | DOI:10.7150/ijms.57987
Source: International Journal of Medical Sciences - June 9, 2021 Category: Biomedical Science Authors: Ming-Jui Hung Nen-Chung Chang Patrick Hu Tien-Hsing Chen Chun-Tai Mao Chi-Tai Yeh Ming-Yow Hung Source Type: research

Effectiveness and safety of rivaroxaban versus warfarin in Taiwanese patients with end-stage renal disease and nonvalvular atrial fibrillation: A real-world nationwide cohort study
ConclusionsIn Taiwanese patients with end-stage renal disease and nonvalvular atrial fibrillation, rivaroxaban may be associated with a similar risk of major bleeding but a lower risk of thromboembolism compared with warfarin. The potential benefit of 10 mg of rivaroxaban in this population requires further investigation.
Source: PLoS One - April 8, 2021 Category: Biomedical Science Authors: Yi-Cheng Lin Source Type: research

Could prokinetic agents protect long-term nasogastric tube-dependent patients from being hospitalized for pneumonia? A nationwide population-based case-crossover study
ConclusionProkinetic agent use had no negative association with pneumonia admission among long-term nasogastric tube-dependent patients in Taiwan.
Source: PLoS One - April 5, 2021 Category: Biomedical Science Authors: Kun-Siang Huang Source Type: research

Association of digoxin with mortality in patients with advanced chronic kidney disease: A population-based cohort study
In conclusion, our study demonstrated that digoxin use was associated with increased mortality, but not cardiovascular events or renal function decline in advanced CKD patients. This finding warns the safety of presc ribing digoxin in this population. Future prospective studies are needed to overcome the limitations of cohort study design.
Source: PLoS One - January 15, 2021 Category: Biomedical Science Authors: Lii-Jia Yang Source Type: research

Stroke risk in hypertrophic cardiomyopathy patients with atrial fibrillation: a nationwide database study.
This study aimed to determine the incidence of stroke and its risk factors in HCM patients with AF during a long-term follow-up. Using a national database, we retrospectively investigated 18,724 HCM patients from a systematic sample of 1,000,000 Taiwanese people between 1997 and 2013. The incidences of AF and stroke were estimated. Data were analyzed using Cox regression models. AF was identified in 598 patients (262 men, mean age 66.3±13.0 years) during a median follow-up of 7.0 years. The AF incidence in HCM patients was 5.83 per 1000 person-years, and the overall incidence of AF-associated stroke was 24.14 per 1000 per...
Source: Aging - November 23, 2020 Category: Biomedical Science Authors: Hsu JC, Huang YT, Lin LY Tags: Aging (Albany NY) Source Type: research

Clinical burden of autosomal dominant polycystic kidney disease.
Abstract There are no specific therapies for autosomal dominant polycystic kidney disease (ADPKD), and clinical data evaluating the effects of non-specific therapies on ADPKD patients are scarce. We therefore evaluated those effects using data from a longitudinal health insurance database collected from 2000-2010. We individually selected patients with and without ADPKD from inpatient data files as well as from the catastrophic illness registry in Taiwan based on 1:5 frequency matching for sex, age, and index year. The hazard ratios (HR) of all-cause mortality, ischemic stroke, hemorrhagic stroke and end-stage ren...
Source: Aging - February 23, 2020 Category: Biomedical Science Authors: Hung PH, Lin CH, Hung KY, Muo CH, Chung MC, Chang CH, Chung CJ Tags: Aging (Albany NY) Source Type: research

ADVANCIS Score Predicts Acute Kidney Injury After Percutaneous Coronary Intervention for Acute Coronary Syndrome.
In conclusion, the ADVANCIS score is a novel, simple, robust tool for predicting the risk of incident AKI after PCI for ACS, and it can aid in risk stratification to monitor patient care. PMID: 29559842 [PubMed - in process]
Source: International Journal of Medical Sciences - March 25, 2018 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

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