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Shengui Sansheng San Ameliorates Cerebral Energy Deficiency via Citrate Cycle After Ischemic Stroke
Conclusion In summary, SSS extraction significantly ameliorates cerebral energy metabolism via boosting citrate cycle, which mainly embodies the enhancements of blood glucose concentration, glucose and lactate transportation and glucose utilization, as well as the regulations of relative enzymes activities in citrate cycle. These ameliorations ultimately resulted in numerous ATP yield after stroke, which improved neurological function and infarcted volume. Collectively, it suggests that SSS extraction has exerted advantageous effect in the treatment of cerebral ischemia. Ethics Statement All animal operations were accor...
Source: Frontiers in Pharmacology - April 22, 2019 Category: Drugs & Pharmacology Source Type: research

What stroke image do we want? European survey on acute stroke imaging and revascularisation treatment
ConclusionThe diagnostic workup and, to a greater extent, the revascularisation treatments of typical stroke patients vary considerably across European countries. This study reinforces the need to compare the quality of stroke care in terms of process and outcomes between countries. Research is also needed to investigate the cost-effectiveness of second-line imaging strategies in acute stroke care.
Source: Health Policy and Technology - August 10, 2019 Category: Health Management Source Type: research

Is carotid imaging underused in patients with transient ischemic attack or ischemic stroke? A Swedish Stroke Register (Riksstroke) study
ConclusionCarotid imaging appears to be underused in patients with TIA and IS. Opportunities of secondary stroke prevention with carotid interventions are likely missed.
Source: Acta Neurologica Scandinavica - December 18, 2017 Category: Neurology Authors: F. Buchwald, B. Norrving, J. Petersson Tags: ORIGINAL ARTICLE Source Type: research

Accuracy of automated intracerebral hemorrhage volume measurement on non-contrast computed tomography: a Swedish Stroke Register cohort study
ConclusionOur study showed excellent agreement in volume quantification between the fully automated software qER –NCCT and manual segmentation of ICH on NCCT. The qER–NCCT would be an important additive tool by aiding in early diagnostics and prognostication for patients with ICH and in provide volumetry on a population-wide level. Further refinement of the software should address the underestimation of IC H volume seen in a portion of large, heterogenous, irregularly shaped ICHs.
Source: Neuroradiology - November 3, 2022 Category: Radiology Source Type: research

What are the images used to diagnose and assess suspected strokes?: A systematic literature review of care in four European countries.
Authors: Peultier AC, Redekop K, Coche E, Severens JL Abstract INTRODUCTION: The cost-effectiveness of clinical interventions is often assessed using current care as comparator. However, evidence suggests practice variation in stroke imaging across countries. For the purpose of feeding into cost-effectiveness analysis, this research aims to describe the patterns of stroke imaging, examine practice variations across countries and, as such, obtain results reflecting current care. Areas covered: A systematic literature review was conducted to identify original studies reporting the imaging workup used in acute stroke ...
Source: Expert Review of Pharmacoeconomics and Outcomes Research - February 7, 2018 Category: Health Management Tags: Expert Rev Pharmacoecon Outcomes Res Source Type: research

Long-term exposure to air pollution, coronary artery calcification, and carotid artery plaques in the population-based Swedish SCAPIS Gothenburg cohort
Environ Res. 2022 Jul 19:113926. doi: 10.1016/j.envres.2022.113926. Online ahead of print.ABSTRACTLong-term exposure to air pollution is associated with cardiovascular events. A main suggested mechanism is that air pollution accelerates the progression of atherosclerosis, yet current evidence is inconsistent regarding the association between air pollution and coronary artery and carotid artery atherosclerosis, which are well-established causes of myocardial infarction and stroke. We studied associations between low levels of long-term air pollution, coronary artery calcium (CAC) score, and the prevalence and area of caroti...
Source: Atherosclerosis - July 22, 2022 Category: Cardiology Authors: Karl Kilbo Edlund Gerd Sallsten Peter Moln ár Eva M Andersson Mikael Ögren David Segersson Erika Fagman Bj örn Fagerberg Lars Barregard G öran Bergström Leo Stockfelt Source Type: research