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Rivaroxaban for the prevention of outcomes in patients with atrial fibrillation in clinical practice: an indirect comparison of national and international registries
Conclusion: Despite the fact that rivaroxaban is prescribed for elderly patients with a high thromboembolic risk, rates of outcomes remain low.PMID:36148923 | DOI:10.2217/cer-2022-0111
Source: Journal of Comparative Effectiveness Research - September 23, 2022 Category: General Medicine Authors: Francisco Marin Marcelo Sanmart ín Fernández I ñaki Lekuona Fernando Arribas Gonzalo Bar ón-Esquivias Vivencio Barrios Juan Cosin-Sales Rom án Freixa-Pamias Jaime Masjuan Alejandro I P érez-Cabeza Vanessa Rold án Schilling Jos é Manuel Vázquez Ro Source Type: research

Another Reason to Get the Flu Shot: Lowered Risk for Stroke
THURSDAY, Sept. 8, 2022 -- As flu season approaches, a new study is pointing to a possible bonus from vaccination: a lower risk of stroke. Researchers in Spain found that among nearly 86,000 middle-aged and older adults, those who got their annual...
Source: Drugs.com - Daily MedNews - September 8, 2022 Category: General Medicine Source Type: news

Economic impact of the first pass effect in mechanical thrombectomy for acute ischaemic stroke treatment in Spain: a cost-effectiveness analysis from the national health system perspective
Conclusion Achieving FPE after MT can lead to better health outcomes per AIS patient and important cost savings for the Spanish NHS.
Source: BMJ Open - September 1, 2022 Category: General Medicine Authors: Gonzalez Diaz, E., Rodriguez-Paz, C., Fernandez-Prieto, A., Martinez-Galdamez, M., Martinez-Moreno, R., Ortega Quintanilla, J., Tomasello, A., Zamarro, J., Liebeskind, D., Zaidat, O. O., Mueller-Kronast, N. H. Tags: Open access, Health economics Source Type: research

Intra-arterial Alteplase vs Placebo After Successful Thrombectomy and Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke —Reply
In Reply In response to the comments by Dr Mai and colleagues about the change in the primary outcome of the CHOICE trial, we would like to provide several clarifications. First, the definition of the primary outcome in the original protocol was submitted for publication on July 15, 2019. Second, the registered protocol (NCT03876119) was first posted on March 15, 2019, but the primary outcome definition was changed and posted on March 19, 2021. Third, the summary of the history of these protocol changes was included in Supplement 2 of the article. As required by Spanish law, these changes were also communicated to the Span...
Source: JAMA - June 28, 2022 Category: General Medicine Source Type: research

Characteristics and management of patients with stroke and major hemorrhagic episodes with atrial fibrillation under vitamin K antagonist therapy. EVENTHO study
CONCLUSIONS: In the sample studied, half of the AF patients who suffered stroke/SE or major hemorrhagic episode had inadequate TTR and, despite this, after hospital discharge, they restarted treatment with VKA. These results highlight the need to evaluate safer and effective therapeutic alternatives in AF patients with poor TTR control after suffering a stroke/SE or major hemorrhagic episode.PMID:35120766 | DOI:10.1016/j.medcli.2021.12.004
Source: Medicina Clinica - February 5, 2022 Category: General Medicine Authors: Olga Gav ín Vanessa Rold án Pilar Llamas-Sillero Amparo Santamar ía Daniel Arum í Susana Fern ández de Cabo Source Type: research

Associated factors with functional prognosis of patients with acute ischemic stroke undergoing thrombectomy
CONCLUSION: Age, T2D and failed recanalization increase risk for unfavorable outcome at 90 days in patients with AIS treated with MT. Procedure time duration should be considered as a possible determinant factor in functional outcome.PMID:35042605 | DOI:10.1016/j.medcli.2021.11.010
Source: Medicina Clinica - January 19, 2022 Category: General Medicine Authors: Íñigo Rodríguez-Baz Mar ía Cristo Rodríguez-Pérez Antonio Medina Rodr íguez Ignacio Hern ández Cabezudo Yolanda Sosa Cabrera Source Type: research

The economic burden of stroke: a systematic review of cost of illness studies
J Med Life. 2021 Sep-Oct;14(5):606-619. doi: 10.25122/jml-2021-0361.ABSTRACTStroke is one of the leading causes of morbidity and mortality worldwide. As the number of stroke cases is rising from one year to another, policymakers require data on the amount spent on stroke to enforce better financing policies for prevention, hospital care, outpatient rehabilitation services and social services. We aimed to systematically assess the economic burden of stroke at global level. Cost of stroke studies were retrieved from five databases. We retrieved the average cost per patient, where specified, or estimated it using a top-down a...
Source: Journal of Medicine and Life - January 14, 2022 Category: General Medicine Authors: Stefan Strilciuc Diana Alecsandra Grad Constantin Radu Diana Chira Adina Stan Marius Ungureanu Adrian Gheorghe Fior-Dafin Muresanu Source Type: research

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