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Condition: Ischemic Stroke
Countries: Singapore Health

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Total 208 results found since Jan 2013.

Temporal Trends and Predictors of Drug Utilization and Outcomes in First-Ever Stroke Patients: A Population-Based Study Using the Singapore Stroke Registry
ConclusionsPrescription of secondary stroke preventive medications (particularly in ischemic stroke) was associated with more favorable outcomes, highlighting the importance of physician adherence to evidence-based pharmacotherapy.
Source: CNS Drugs - July 15, 2019 Category: Neurology Source Type: research

Adherence to the Mediterranean diet and risk of stroke and stroke subtypes
AbstractSeveral meta-analyses including a small number of cohorts showed inverse associations between the Mediterranean Diet (MedDiet) and risk of stroke. However, it remains unclear whether such a relation varies by region of the study population or by major subtypes of stroke. We searched PubMed and EMBASE databases for relevant studies and we further included unpublished results from the Singapore Chinese Health Study (N = 57,078) and the Seguimiento Universidad de Navarra (SUN) study (N  =  12,670). We used a random-effects model to calculate summary relative risk (RR) with 95% confidence intervals (CI) of stro...
Source: European Journal of Epidemiology - March 1, 2019 Category: Epidemiology Source Type: research

The Relationship Between Ambient Air Pollution and Acute Ischemic Stroke: A Time-Stratified Case-Crossover Study in a City-State With Seasonal Exposure to the Southeast Asian Haze Problem
ConclusionWe found a short-term elevated risk of ischemic stroke after exposure to air pollution. These findings have public health implications for stroke prevention and emergency health services delivery.
Source: Annals of Emergency Medicine - August 30, 2018 Category: Emergency Medicine Source Type: research

Influence of chronic kidney disease and haemodialysis on stroke outcome
CONCLUSION: Despite significant functional and neurological improvements following rehabilitation, stroke patients with underlying CKD had higher average duration of hospital stay, more recurrent hospitalisations and poorer survival outcomes than those without underlying CKD. This could be attributed to the complications associated with CKD rather than stroke. Multidisciplinary community rehabilitation may be an alternative to reduce recurrent hospitalisations and morbidity in this group of patients. PMID: 32241068 [PubMed - as supplied by publisher]
Source: Singapore Medical Journal - April 2, 2020 Category: General Medicine Authors: Pande SD, Morris J Tags: Singapore Med J Source Type: research

Wake-up Stroke and Onset-to-door Duration Delays: Potential Future Indications for Reperfusion Therapy.
Conclusion: The one- third proportion of wake-up stroke in this cohort and low prevalence of relative contraindications suggest this is a promising group for emerging thrombolysis indications. With the majority of patients presenting after 8 hours, widening of the therapeutic window with new potential reperfusion treatments would not appreciably increase treatment utilisation. This study reaffirms the urgent need for public education to improve stroke awareness in Singapore. PMID: 24557460 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 1, 2014 Category: Journals (General) Authors: Tan MSh, Ang ES, Ho SS, Ng SC, Talabucon L, Woon FP, De Silva DA Tags: Ann Acad Med Singapore Source Type: research

Surveys of Stroke Patients and Their Next of Kin on Their Opinions towards Decision-Making and Consent for Stroke Thrombolysis.
CONCLUSION: The survey found that in the decision-making process for stroke thrombolysis, there was no clear consensus on the preference for the decision maker of the mentally incapacitated patient. In Singapore, there is a strong influence of the NOK in decision-making for thrombolysis. PMID: 28263342 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 31, 2017 Category: Journals (General) Authors: Angamuthu N, Queck KK, Menon S, Ho SS, Ang E, De Silva DA Tags: Ann Acad Med Singapore Source Type: research

ACT-FAST: a quality improvement project to increase the percentage of acute stroke patients receiving intravenous thrombolysis within 60 minutes of arrival at the emergency department.
CONCLUSION: The interventions resulted in an increasing but non-significant trend of acute stroke patients receiving thrombolysis within 60 minutes. Outcomes will be monitored for a longer duration to demonstrate trends and sustainability. PMID: 32227791 [PubMed - as supplied by publisher]
Source: Singapore Medical Journal - March 30, 2020 Category: General Medicine Authors: Chiu LQ, Quek DYJ, Salihan RB, Ng WM, Othman RB, Lee CH, Oh DCT Tags: Singapore Med J Source Type: research

Independent predictors of medication adherence among Singaporean patients following an ischemic stroke or transient ischemic attack
ConclusionMedication adherence was poor in Singaporean patients following an ischemic stroke or transient ischemic attack. The independent predictors identified in this study will support healthcare professionals to develop tailored intervention to improve medication adherence among this group of patients. Relevance to clinical practiceNurses play an important role in promoting patients’ medication adherence. Helping stroke patients understand the long‐term benefits of their medications is essential to enhance patients’ medication adherence and results in better health outcomes.This article is protected by copyright....
Source: Journal of Clinical Nursing - August 9, 2017 Category: Nursing Authors: Wenru Wang, Gerk Sin Chia, Il Fan Tan, Siew Noi Janis Tye, Xiaona Wang, Birong Zhu, Ying Jiang Tags: Original Article Source Type: research

Independent predictors of medication adherence among Singaporean patients following an ischaemic stroke or transient ischaemic attack
ConclusionMedication adherence was poor in Singaporean patients following an ischaemic stroke or transient ischaemic attack. The independent predictors identified in this study will support healthcare professionals to develop tailored intervention to improve medication adherence among this group of patients. Relevance to clinical practiceNurses play an important role in promoting patients’ medication adherence. Helping stroke patients understand the long‐term benefits of their medications is essential to enhance patients’ medication adherence and results in better health outcomes.
Source: Journal of Clinical Nursing - October 8, 2017 Category: Nursing Authors: Wenru Wang, Gerk Sin Chia, Il Fan Tan, Siew Noi Janis Tye, Xiaona Wang, Birong Zhu, Ying Jiang Tags: ORIGINAL ARTICLE Source Type: research

Serum S100 β as a predictor of severity and outcomes for mixed subtype acute ischaemic stroke.
CONCLUSION: High serum S100β is associated with unfavourable outcome for mixed subtype AIS. Cut-off values of S100β72hrs and ∆S100β were optimal for predicting unfavourable stroke outcome. PMID: 31317198 [PubMed - as supplied by publisher]
Source: Singapore Medical Journal - July 10, 2019 Category: General Medicine Authors: Sakdejayont S, Pruphetkaew N, Chongphattararot P, Nanphan P, Sathirapanya P Tags: Singapore Med J Source Type: research

Temporal Trends and Patient Characteristics Associated With Drug Utilisation After First-Ever Stroke: Insights From Chronic Disease Registry Data in Singapore.
CONCLUSION: This study reveals changes in prescription behaviour over time in a multiethnic Asian population with first-ever stroke. Patient characteristics including younger age, Malay ethnicity and certain comorbidities (i.e. hyperlipidaemia, atrial fibrillation) were associated with the combined use of all 3 guideline medications among ischaemic stroke patients. PMID: 32301477 [PubMed - in process]
Source: Ann Acad Med Singapo... - February 29, 2020 Category: General Medicine Authors: Yeo SH, Toh MPH, Lee SH, Seet RC, Wong LY, Yau WP Tags: Ann Acad Med Singapore Source Type: research

Long term Post-Stroke Functional Outcomes: a comparison of diabetics and non-diabetics
Conclusions: DM was associated with poor functional outcomes following ischemic stroke in the long term with the effect remaining consistent throughout the 7-year follow-up period. Age modified the effe ct of DM in the long term, with an observed increase in risk in the ≤65 age group but not in the>65 age group.
Source: Cerebrovascular Diseases Extra - December 13, 2021 Category: Neurology Source Type: research

Long-Term Post-Stroke Functional Outcomes: A Comparison of Diabetics and Nondiabetics
Conclusions: DM was associated with poor functional outcomes following ischemic stroke in the long term, with the effect remaining consistent throughout the 7-year follow-up period. Age modified the effect of DM in the long term, with an observed increase in risk in the ≤65 age-group but not in the #x3e;65 age-group.Cerebrovasc Dis Extra 2022;12:7 –13
Source: Cerebrovascular Diseases Extra - December 13, 2021 Category: Neurology Source Type: research

Predicting Pneumonia in Acute Ischaemic Stroke: Comparison of Five Prediction Scoring Models.
CONCLUSION: A(2)DS(2) , AIS-APS and Kwon's scores performed comparably in discriminating SAP in AIS patients. PMID: 28733688 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - June 1, 2017 Category: General Medicine Authors: Tu TM, Phua SS, Acharyya S, Ng WM, Oh DC Tags: Ann Acad Med Singapore Source Type: research

Long-term outcomes of ischaemic stroke patients with diabetes in a multi-ethnic cohort in Singapore
CONCLUSION: Our study provides quantitative data on the event rates of ischaemic stroke patients with diabetes. These findings provide insights on stroke predictors in a multi-ethnic Asian population, which may have implications in the design of future interventional studies.PMID:33623954 | DOI:10.47102/annals-acadmedsg.2020105
Source: Ann Acad Med Singapo... - February 24, 2021 Category: General Medicine Authors: Ei Zune The Mei Yen Ng Geelyn JL Ng Bernadette GC Er Amy ML Quek Prakash Paliwal Leonard L Yeo Bernard Chan Vijay K Sharma Hock Luen Teoh Eric YH Khoo Raymond CS Seet Source Type: research