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An international cluster randomized quality-improvement trial to increase the adherence to evidence-based therapies for acute ischemic stroke and transient ischemic attack patients: Rationale and design of the BRIDGE STROKE trial
Publication date: Available online 30 September 2018Source: American Heart JournalAuthor(s): Maria Julia Machline-Carrion, Eliana Vieira Santucci, Lucas Petri Damiani, Cecilia Bahit, Germán Málaga, Octávio Marques Ponte-Neto, Sheila Cristina Ouriques Martins, Viviane Flumignan Zétola, Karina Normilio-Silva, Gabriel Rodrigues de Freitas, Alessandra Gorgulho, Antônio De Salles, Beatriz Gonzales Pacheco da Silva, Juliana Yamashita Santos, Isabella de Andrade Jesuíno, Priscila Regina Torres Bueno, Alexandre Biasi Cavalcanti, Hélio Penna Guimarães, Ying Xian, Janet Prvu BettgerAbstractBackgroundTranslating evidence into...
Source: American Heart Journal - October 4, 2018 Category: Cardiology Source Type: research

An international cluster-randomized quality improvement trial to increase the adherence to evidence-based therapies for acute ischemic stroke and transient ischemic attack patients: Rationale and design of the BRIDGE STROKE Trial
Publication date: January 2019Source: American Heart Journal, Volume 207Author(s): Maria Julia Machline-Carrion, Eliana Vieira Santucci, Lucas Petri Damiani, Cecilia Bahit, Germán Málaga, Octávio Marques Pontes-Neto, Sheila Cristina Ouriques Martins, Viviane Flumignan Zétola, Karina Normilio-Silva, Gabriel Rodrigues de Freitas, Alessandra Gorgulho, Antônio De Salles, Beatriz Gonzales Pacheco da Silva, Juliana Yamashita Santos, Isabella de Andrade Jesuíno, Priscila Regina Torres Bueno, Alexandre Biasi Cavalcanti, Hélio Penna Guimarães, Ying Xian, Janet Prvu BettgerBackgroundTranslating evidence into clinical practic...
Source: American Heart Journal - November 9, 2018 Category: Cardiology Source Type: research

Challenges of Thrombolysis in a Developing Country: Characteristics and Outcomes in Peru
Background: The availability of intravenous tissue plasminogen activator (IV-tPA) remains limited worldwide, especially in low-income countries, where the burden of disability due to ischemic stroke is the highest. Aims: To evaluate outcomes and safety of IV-tPA at the only Peruvian reference institute for neurologic diseases. Methods: We conducted a prospective, observational study of stroke patients who received IV-tPA between 2009 and 2016. We assessed characteristics associated with good outcome (modified Rankine scale 0-2) at 3 months using a multivariate regression model; and factors correlated with clinical improvem...
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2020 Category: Neurology Authors: Carlos Abanto, Ana Valencia, Pilar Calle, Danny Barrientos, N éstor Flores, María Novoa, Rosa L. Ecos, Jorge Alonso Ramirez, Angela K. Ulrich, Joseph R. Zunt, David L. Tirschwell, Sarah Wahlster Source Type: research

One year prognosis after suffering the onset of cerebrovascular disease in patients from a public hospital in Lima, Peru.
Authors: Alvarado-Dulanto CM, Lazo Mde L, Loza-Herrera JD, Málaga G Abstract In Latin America, there is almost nonexistense information about the prognosis of patients with stroke. We tried to find one- year vital and functional prognosis from patients with "first-ever stroke". We did a prospective cohort study, recruiting patients in the medicine service of a public hospital, and follow them up to one year after their first-ever stroke. We collected baseline data, such as previous medical history and information about their stroke. We found mortality proportions, differences among subgroups, and compared their ac...
Source: Revista Peruana de Medicina de Experimental y Salud Publica - December 11, 2015 Category: Global & Universal Tags: Rev Peru Med Exp Salud Publica Source Type: research

Intrinsic capacity and its associations with incident dependence and mortality in 10/66 Dementia Research Group studies in Latin America, India, and China: A population-based cohort study
ConclusionsIn this study we observed a high prevalence of DICs, particularly in older age groups. Those affected had substantially increased risks of dependence and death. Most needs for care arose in those with DIC yet to become frail. Our findings provide some support for the strategy of optimising intrinsic capacity in pursuit of healthy ageing. Implementation at scale requires community-based screening and assessment, and a stepped-care intervention approach, with redefined roles for community healthcare workers and efforts to engage, train, and support them in these tasks. ICOPE might be usefully integrated into commu...
Source: PLoS Medicine - September 14, 2021 Category: Internal Medicine Authors: Martin J. Prince Source Type: research