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Total 64 results found since Jan 2013.

The interactive effect of diabetes and central obesity on stroke: a prospective cohort study of inner Mongolians
Conclusions: The participants who were both diabetic and centrally obese had significantly higher risk for incident stroke than the combination of individuals who individually had either condition among Mongolian population. This study suggests that central obesity and diabetes act synergistically to increase the risk of stroke.
Source: BMC Neurology - April 28, 2015 Category: Neurology Authors: Jennifer OlofindayoHao PengYan LiuHongmei LiMingzhi ZhangAili WangYonghong Zhang Source Type: research

Combined Effects of Family History of Cardiovascular Disease and Serum C-reactive Protein Level on the Risk of Stroke: A 9.2-year Prospective Study among Mongolians in China.
CONCLUSION: Participants with both a family history of CVD and high CRP levels had the highest stroke incidence, suggesting that high CRP levels may increase stroke risk, especially of ischemic stroke, among individuals with a family history of CVD. PMID: 29081337 [PubMed - in process]
Source: Biomedical and Environmental Sciences : BES - September 1, 2017 Category: Biomedical Science Authors: Zhu ZB, Huangfu XF, Zhong CK, Zhou YP, Tian YF, Buren B, Xu T, Wang AL, Li HM, Zhang MZ, Zhang YH Tags: Biomed Environ Sci Source Type: research

Combined Effects of A Body Shape Index and Serum C-reactive Protein on Ischemic Stroke Incidence among Mongolians in China.
CONCLUSION: We found that participants with simultaneously high ABSI and high CRP levels had the highest risk of ischemic stroke in the Mongolian population. Our findings suggest that the combination of high ABSI and high CRP levels may increase the risk of ischemic stroke. PMID: 30987691 [PubMed - in process]
Source: Biomedical and Environmental Sciences : BES - February 28, 2019 Category: Biomedical Science Authors: Wang GL, Zhang R, Zhou YT, Wang AL, Xu T, Zhang MZ, Li HM, Zhang YH Tags: Biomed Environ Sci Source Type: research

Chungkookjang, a soy food, fermented with Bacillus amyloliquefaciens protects gerbils against ishcmeic stroke injury, and post-stroke hyperglycemia
In conclusion, the daily intake of chungkookjang fermented with B. amyloliquefaciens improved the gut microbiome, increased blood flow to the brain, suppressed systemic inflammation, and may reduce the susceptibility to injury from ischemic stroke in gerbils subjected to ischemic injury.Graphical abstract
Source: Food Research International - October 31, 2019 Category: Food Science Source Type: research

Combined Effects of Family History of Cardiovascular Disease and Serum C-reactive Protein Level on the Risk of Stroke: A 9.2-year Prospective Study among Mongolians in China
Conclusion Participants with both a family history of CVD and high CRP levels had the highest stroke incidence, suggesting that high CRP levels may increase stroke risk, especially of ischemic stroke, among individuals with a family history of CVD.
Source: Biomedical and Environmental Sciences - November 19, 2017 Category: Biomedical Science Source Type: research

Combined Effects of A Body Shape Index and Serum C-reactive Protein on Ischemic Stroke Incidence among Mongolians in China
ConclusionWe found that participants with simultaneously high ABSI and high CRP levels had the highest risk of ischemic stroke in the Mongolian population. Our findings suggest that the combination of high ABSI and high CRP levels may increase the risk of ischemic stroke.
Source: Biomedical and Environmental Sciences - July 4, 2019 Category: Biomedical Science Source Type: research

Hypertension and elevated C-reactive protein: Future risk of ischemic stroke in a prospective cohort study among inner Mongolians in China
Hypertension and C-reactive protein (CRP) have been investigated extensively in regard to risk of stroke and cardiovascular disease in population. However, few studies have paid an attention to the cumulative effect of hypertension and CRP on the development of ischemic stroke, and there are no published studies regarding cumulative effect of hypertension and CRP on the ischemic stroke incidence in an Inner Mongolian population. The purpose of present study is to assess the association between hypertension, CRP and the future risk of ischemic stroke, and the potential role of CRP to enhance risk prediction of ischemic stro...
Source: International Journal of Cardiology - April 24, 2014 Category: Cardiology Authors: Aili Wang, Tan Xu, Tian Xu, Mingzhi Zhang, Hongmei Li, Weijun Tong, Yonghong Zhang Tags: Letters to the Editor Source Type: research

Blood Pressure Components and Stroke in Inner Mongolians - A Prospective Cohort Study
Introduction. Stroke is the leading cause of disability and the second-leading cause of death in the world [1]. It is becoming an ever-increasing public health burden in China [2]. There is a strong association between both systolic blood pressure (SBP) and diastolic blood pressure (DBP) and stroke, but even in cases of normal BP stroke can still occur [3]. This indicates that other risk factors and BP components other than SBP or DBP may play a role in the development of stroke. In addition to SBP and DBP, BP is also characterized by pulse pressure (PP) and mean arterial pressure (MAP).
Source: International Journal of Cardiology - August 2, 2014 Category: Cardiology Authors: Hao Peng, Anna Tan, Shuhai Han, Zhong Ju, Aili Wang, Yonghong Zhang Source Type: research

Blood pressure components and stroke in Inner Mongolians — A prospective cohort study
Stroke is the leading cause of disability and the second-leading cause of death in the world [1]. It is becoming an ever-increasing public health burden in China [2]. There is a strong association between both systolic blood pressure (SBP) and diastolic blood pressure (DBP) and stroke, but even in cases of normal BP stroke can still occur [3]. This indicates that other risk factors and BP components other than SBP or DBP may play a role in the development of stroke. In addition to SBP and DBP, BP is also characterized by pulse pressure (PP) and mean arterial pressure (MAP).
Source: International Journal of Cardiology - August 2, 2014 Category: Cardiology Authors: Hao Peng, Anna Tan, Shuhai Han, Zhong Ju, Aili Wang, Yonghong Zhang Source Type: research

Neuroprotective effect of epidermal growth factor plus growth hormone-releasing peptide-6 resembles hypothermia in experimental stroke.
DISCUSSION: With hypothermia being a good standard neuroprotectant reference, these results provide additional proof of principle for EGF and GHRP-6 co-administration as a potentially neuroprotective stroke therapy. PMID: 27665924 [PubMed - as supplied by publisher]
Source: Neurological Research - September 27, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Assessment of dose-effect and therapeutic time window in preclinical studies of rhEGF and GHRP-6 coadministration for stroke therapy.
Authors: Subirós N, Pérez-Saad HM, Berlanga JA, Aldana L, García-Illera G, Gibson CL, García-Del-Barco D Abstract BACKGROUND: Stroke continues to be a leading cause of mortality and morbidity worldwide, and novel therapeutic options for ischaemic stroke are urgently needed. In this context, drug combination therapies seem to be a viable approach, which has not been fully explored in preclinical studies. OBJECTIVES: In this work, we assessed the dose-response relationship and therapeutic time window, in global brain ischaemia, of a combined therapeutic approach of recombinant human epidermal growth factor (E...
Source: Neurological Research - August 29, 2015 Category: Neurology Tags: Neurol Res Source Type: research

C-reactive Protein Level, Apolipoprotein B-to-apolipoprotein A-1 Ratio, and Risks of Ischemic Stroke and Coronary Heart Disease among Inner Mongolians in China.
CONCLUSION: High CRP level with high ApoB/ApoA-1 ratio was associated with the highest risks of IS and CHD in the Mongolian population. This study suggests that the combination of high CRP and ApoB/ApoA-1 ratio may improve the assessment of future risk of developing IS and CHD in the general population. PMID: 27554116 [PubMed - in process]
Source: Biomedical and Environmental Sciences : BES - June 30, 2016 Category: Biomedical Science Authors: Tian YF, Zhou YP, Zhong CK, Buren B, Xu T, Li HM, Zhang MZ, Wang AL, Zhang YH Tags: Biomed Environ Sci Source Type: research

Traditional Mongolian medicine Eerdun Wurile improves stroke recovery through regulation of gene expression in rat brain
Conclusion Our data collectively indicated that EW enhances expression of growth factors including Igf1 and Igf2 in neurons and microglia, and may stimulate microglia polarization in the brain. The consequences of such activity include stimulation of neuron growth, hydrolysis and clearance of cell debris at the lesion, as well as the angiogenesis. Graphical abstract
Source: Journal of Ethnopharmacology - May 26, 2018 Category: Drugs & Pharmacology Source Type: research

Effect of arginine vasopressin on the cortex edema in the ischemic stroke of mongolian gerbils
• Ischemic stroke increased arginine vasopressin (AVP) levels in the cortex and decreased the cortex specific gravities (edema).• There were many negative relationships between the cortex edema and AVP concentration.• Intranasal AVP aggravated the focal cortex edema, but intranasal AVP receptor antagonist mitigated that edema.• There were not changes of the cortex edema and AVP concentration in the non-ischemic cortex.• AVP participated in the process of ischemia-evoked cortex edema.
Source: Neuropeptides - March 24, 2015 Category: Neuroscience Authors: Xue-Yan Zhao, Chun-Fang Wu, Jun Yang, Yang Gao, Zhi-Xiu Song, Fang-Jie Sun, Le-Le Bao, Da-Xin Wang, Chang-Hong Wang, Bao-Cheng Lin Source Type: research