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Total 139 results found since Jan 2013.

Apparent Treatment-Resistant Hypertension Among Stroke Survivors: A Transcontinental Study assessing impact of race and geography
CONCLUSIONS: Future studies are needed to investigate the contribution of socioeconomic disparities in the prevalence aTRH in those with African Ancestry to explore the long-term impact, and evaluate effective therapeutic interventions in this subpopulation.PMID:35366323 | DOI:10.1093/ajh/hpac046
Source: American Journal of Hypertension - April 2, 2022 Category: Cardiology Authors: Fred Stephen Sarfo Esther Olasoji Grant P Banfill Bruce Ovbiagele Alexis N Simpkins Source Type: research

A cardiovascular polypill for secondary stroke prevention in a tertiary centre in Ghana (SMAART): a phase 2 randomised clinical trial
Lancet Glob Health. 2023 Oct;11(10):e1619-e1628. doi: 10.1016/S2214-109X(23)00347-9.ABSTRACTBACKGROUND: A cardiovascular polypill containing generic drugs might facilitate sustained implementation of and adherence to evidence-based treatments, especially in resource-limited settings. However, the impact of a cardiovascular polypill in mitigating atherosclerotic risk among stroke survivors has not been assessed. We aimed to compare a polypill regimen with usual care on carotid intima-media thickness (CIMT) regression after ischaemic stroke.METHODS: In SMAART, a phase 2 parallel, open-label, assessor-masked, randomised clini...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Fred Stephen Sarfo Jenifer Voeks Sheila Adamu Benedict Apaw Agyei Manolo Agbenorku Nyantakyi Adu-Darko Mercy Adomah Oteng Vida Obese Rexford Adu Gyamfi Nathaniel Adusei Mensah Raelle Tagge Michael Ampofo Samuel Amoabeng Kontoh Samuel Blay Nguah Bruce Ovbi Source Type: research

Capacity-Building for Stroke Genomic Research Data Collection: The African Neurobiobank Ethical, Legal, and Social Implications Project Experience
Conclusion: Capacity-building is a necessary step toward ELSI-related genomic research implementation in African countries where scholarship of ELSI of genomics research is emerging. Our findings may be useful to the design and implementation of ELSI-GGR projects in other African countries.PMID:35759418 | DOI:10.1089/bio.2021.0144
Source: Biopreservation and Biobanking - June 27, 2022 Category: Biomedical Science Authors: Ezinne O Uvere Michelle Nichols Babatunde R Ojebuyi Suleiman Yahaya Isah Benedict Calys-Tagoe Carolyn Jenkins Reginald Obiako Lukman Owolabi Albert Akpalu Fred Stephen Sarfo Olumayowa Ogunronbi Muyiwa Adigun Gregory Adekunle Fakunle Bello Hamzat Ruth Lary Source Type: research

Pilot trial of a tele-rehab intervention to improve outcomes after stroke in Ghana: A feasibility and user satisfaction study
Tele-rehabilitation after stroke holds promise for under-resourced settings, especially sub-Saharan Africa (SSA), with its immense stroke burden and severely limited physical therapy services.
Source: Journal of the Neurological Sciences - February 2, 2018 Category: Neurology Authors: Fred S. Sarfo, Nathaniel Adusei, Michael Ampofo, Frank K. Kpeme, Bruce Ovbiagele Tags: Clinical Short Communication Source Type: research

Incident stroke among Ghanaians with hypertension and diabetes: A multicenter, prospective cohort study
The burden of stroke among hypertensive and diabetic population in sub-Saharan Africa remains high. We sought to identify the risk factors associated with stroke occurrence in these high-risk population groups.
Source: Journal of the Neurological Sciences - September 13, 2018 Category: Neurology Authors: Fred S. Sarfo, Linda M. Mobula, Jacob Plange-Rhule, Daniel Ansong, David Ofori-Adjei Source Type: research

Estimated glomerular filtration rate predicts incident stroke among ghanaians with diabetes and hypertension
This study sought to fill this knowledge gap.
Source: Journal of the Neurological Sciences - September 20, 2018 Category: Neurology Authors: Fred Stephen Sarfo, Linda Meta Mobula, Osei Sarfo-Kantanka, Sheila Adamu, Jacob Plange-Rhule, Daniel Ansong, Rexford Adu Gyamfi, James Duah, Bertha Abraham, David Ofori-Adjei Source Type: research

Estimated glomerular filtration rate predicts incident stroke among Ghanaians with diabetes and hypertension
This study sought to fill this knowledge gap.
Source: Journal of the Neurological Sciences - November 15, 2018 Category: Neurology Authors: Fred Stephen Sarfo, Linda Meta Mobula, Osei Sarfo-Kantanka, Sheila Adamu, Jacob Plange-Rhule, Daniel Ansong, Rexford Adu Gyamfi, James Duah, Bertha Abraham, David Ofori-Adjei Tags: Clinical short communication Source Type: research

Response by Sarfo to letter regarding “Patients with hypertension and/or diabetes and incident stroke: A risk assessment”
We sincerely thank Dr. Kawada for his interest in our study titled ‘Incident stroke among Ghanaians with hypertension and diabetes: a multicenter, prospective study’. The aim of our study [1] was to assess the rates and determinants of incident stroke among a prospective, hospital-based Ghanaian cohort with hypertension and or type 2 diabetes mellitus. In this regard, our study was not designed to “evaluate the risk of hypertension and diabetes for incident stroke” as specified by our correspondents.
Source: Journal of the Neurological Sciences - December 13, 2018 Category: Neurology Authors: Fred S. Sarfo Tags: Letter to the Editor Source Type: research

Prevalence, Trajectory, and Predictors of Poststroke Fatigue among Ghanaians
Poststroke fatigue (PSF) is rife among stroke survivors and it exerts a detrimental toll on recovery from functional deficits. The burden of PSF is unknown in sub-Saharan Africa. We have assessed the prevalence, trajectory, and predictors of PSF among 60 recent Ghanaian stroke patients.
Source: Journal of Stroke and Cerebrovascular Diseases - February 20, 2019 Category: Neurology Authors: Fred S. Sarfo, Patrick Berchie, Arti Singh, Michelle Nichols, Maria Agyei-Frimpong, Carolyn Jenkins, Bruce Ovbiagele, On behalf of PINGS Study Investigators Source Type: research

Post-intervention qualitative assessment of mobile health technology to manage hypertension among Ghanaian stroke survivors
Stroke is a leading cause of death in Africa and a key modifiable risk factor for the index and recurrent stroke is through the adequate management of blood pressure. Recent guidelines encourage management beyond clinic settings, yet implementation of these guidelines can be challenging, especially in resource constrained regions, such as in Sub-Saharan Africa. Mobile health technology may offer an innovative and cost-effective approach to improve BP monitoring and facilitate adherence to antihypertensive medications.
Source: Journal of the Neurological Sciences - September 12, 2019 Category: Neurology Authors: Michelle Nichols, Arti Singh, Fred Stephen Sarfo, Frank Treiber, Raelle Tagge, Carolyn Jenkins, Bruce Ovbiagele Source Type: research

Prevalence and predictors of post-stroke epilepsy among Ghanaian stroke survivors
Post-stroke epilepsy (PSE) is associated with poorer quality of life, higher mortality, and greater health expenditures. We are unaware of any published reports on the frequency of and factors associated with PSE in Africa.
Source: Journal of the Neurological Sciences - September 10, 2020 Category: Neurology Authors: Fred Stephen Sarfo, John Akassi, Vida Obese, Sheila Adamu, Manolo Agbenorku, Bruce Ovbiagele Source Type: research

Key determinants of long-term post-stroke mortality in Ghana
Stroke affects a predominantly young to middle-aged population in Africa and is associated with poor outcomes. There are limited data on patient-level determinants of long-term stroke survival on the continent.
Source: Journal of the Neurological Sciences - December 28, 2021 Category: Neurology Authors: Fred Stephen Sarfo, Bruce Ovbiagele Source Type: research

Feasibility, acceptability, and appropriateness of a mobile health stroke intervention among Ghanaian health workers
mHealth interventions can improve care delivery in settings with limited resources. The Phone-based Interventions under Nurse Guidance after Stroke (PINGS) is a nurse-led, mHealth-centered approach to blood pressure (BP) control among recent stroke survivors with hypertension in Ghana. It has 4 key components: (1) home blood pressure monitoring, (2) nurse-coordinated mhealth consults, (3) phone alerts as medication reminders, and (4) patient motivational messages delivered as interactive voice recordings.
Source: Journal of the Neurological Sciences - June 3, 2022 Category: Neurology Authors: JohnH. Amuasi, Melvin K. Agbogbatey, Fred S. Sarfo, Alexis Beyuo, Kwaku Duah, Patrick Agasiya, Agnes Arthur, Lambert Appiah, Samuel B. Nguah, Ansumana Bockarie, Nana K. Ayisi-Boateng, Kwadwo Gyebi Agyenim Boateng, Nathaniel Adusei-Mensah, Albert Akpalu, B Source Type: research