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Outcomes with IV tenecteplase and IV alteplase for acute ischemic stroke with or without thrombectomy in real-world settings in the United States
J Stroke Cerebrovasc Dis. 2022 Dec 6;32(2):106898. doi: 10.1016/j.jstrokecerebrovasdis.2022.106898. Online ahead of print.NO ABSTRACTPMID:36493706 | DOI:10.1016/j.jstrokecerebrovasdis.2022.106898
Source: Atherosclerosis - December 9, 2022 Category: Cardiology Authors: Adnan I Qureshi William I Baskett Navpreet K Bains Brandi R French Farhan Siddiq Camilo R Gomez Chi-Ren Shyu Source Type: research

Tenecteplase in acute ischemic stroke: Review of the literature and expert consensus from the French Neurovascular Society
CONCLUSIONS: These expert consensus statements could provide a framework to guide the clinical decision-making process for the use of tenecteplase according to admission characteristics of AIS patients. However, existing data are limited, requiring inclusions in ongoing RCTs or real-life registries.PMID:36369068 | DOI:10.1016/j.neurol.2022.08.005
Source: Revue Neurologique - November 11, 2022 Category: Neurology Authors: S Olindo J-F Albucher Y Bejot J Berge C Cordonnier B Guillon D Sablot J Tardy S Alamowitch I Sibon Source Type: research

Use of a sheathless 8-French balloon guide catheter (Walrus) through the radial artery for mechanical thrombectomy: technique and case series
Conclusions The use of this sheathless catheter for transradial access was safe and feasible. The technique can potentially improve the outcomes of transradial access for stroke intervention.
Source: Journal of NeuroInterventional Surgery - April 19, 2022 Category: Neurosurgery Authors: Dossani, R. H., Waqas, M., Monteiro, A., Cappuzzo, J. M., Almayman, F., Snyder, K. V., Levy, E. I., Siddiqui, A. H., Davies, J. M. Tags: New devices and techniques Source Type: research

Influence of Sex on Stroke Prognosis: A Demographic, Clinical, and Molecular Analysis
Conclusion Our data suggest that women who suffer from IS present with a poorer functional outcome than men at 3-months, regardless of other preclinical and clinical factors during the acute phase. These relationships seem to be mediated by atrial dysfunction and inflammation. The inflammatory response is slightly higher in women; however, there are no sex differences in their functional behavior. There is a probable relationship between the molecular marker of atrial dysfunction NT-proBNP and worse functional outcome in women, and the connection seems to be more important in cardioembolic stroke patients. In patients wi...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

Frequency of Hemorrhage on Follow Up Imaging in Stroke Patients Treated With rt-PA Depending on Clinical Course
Conclusions: Frequency of hemorrhagic transformation in Routine follow-up brain imaging and consecutive changes in therapeutic management were different depending on clinical course measured by NHISS score. Introduction Brain imaging 24–36 h after systemic thrombolysis for acute ischemic stroke is recommended in American Stroke Association and European Stroke Organization guidelines (1, 2). Brain imaging is performed to detect secondary bleeding or hemorrhagic transformation in order to adapt medical stroke prevention if necessary. Guideline recommendations are based on the results of the first study on rt-PA...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research