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Total 106 results found since Jan 2013.

Eliminating Medication Copayments for Low-income Older Adults at High Cardiovascular Risk: A Randomized Controlled Trial
Conclusions: In low-income adults at high cardiovascular risk, eliminating copayments (average $35 a month) did not improve clinical outcomes or reduce healthcare costs, despite a modest improvement in adherence to medications.PMID:36871215 | DOI:10.1161/CIRCULATIONAHA.123.064188
Source: Circulation - March 5, 2023 Category: Cardiology Authors: David J T Campbell Chad Mitchell Brenda R Hemmelgarn Marcello Tonelli Peter Faris Jianguo Zhang Ross T Tsuyuki Jane Fletcher Flora Au Scott Klarenbach Derek V Exner Braden J Manns Interdisciplinary Chronic Disease Collaboration Source Type: research

Self-management Support Using Advertising Principles for Older Low Income Adults at High Cardiovascular Risk: a Randomized Controlled Trial
Conclusions: In low-income older adults, a tailored SMES program using advertising principles reduced the rate of clinical outcomes compared with usual care, though the mechanisms of improvement are unclear and further studies are required.PMID:36871212 | DOI:10.1161/CIRCULATIONAHA.123.064189
Source: Circulation - March 5, 2023 Category: Cardiology Authors: David J T Campbell Marcello Tonelli Brenda R Hemmelgarn Peter Faris Jianguo Zhang Flora Au Ross T Tsuyuki Chad Mitchell Raj Pannu Tavis Campbell Noah Ivers Jane Fletcher Derek V Exner Braden J Manns Interdisciplinary Chronic Disease Collaboration Source Type: research

Original Article: Increased Stroke Severity and Mortality in Patients with SARS-CoV-2 Infection: An Analysis from the N3C Database
Studies from early in the COVID-19 pandemic showed that patients with ischemic stroke and concurrent SARS-CoV-2 infection had increased stroke severity. We aimed to test the hypothesis that this association persisted throughout the first year of the pandemic and that a similar increase in stroke severity was present in patients with hemorrhagic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 10, 2023 Category: Neurology Authors: Jackson A Narrett, Indika Mallawaarachchi, Chad M. Aldridge, Ethan D Assefa, Arti Patel, Johanna J Loomba, Sarah Ratcliffe, Ofer Sadan, Teshamae Monteith, Bradford B Worrall, Donald E Brown, Karen C Johnston, Andrew M Southerland, N3C consortium Source Type: research

Increased stroke severity and mortality in patients with SARS-CoV-2 infection: An analysis from the N3C database
Studies from early in the COVID-19 pandemic showed that patients with ischemic stroke and concurrent SARS-CoV-2 infection had increased stroke severity. We aimed to test the hypothesis that this association persisted throughout the first year of the pandemic and that a similar increase in stroke severity was present in patients with hemorrhagic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 10, 2023 Category: Neurology Authors: Jackson A Narrett, Indika Mallawaarachchi, Chad M. Aldridge, Ethan D Assefa, Arti Patel, Johanna J Loomba, Sarah Ratcliffe, Ofer Sadan, Teshamae Monteith, Bradford B Worrall, Donald E Brown, Karen C Johnston, Andrew M Southerland, N3C consortium Source Type: research

Transcatheter heart valve selection in patients with low ejection fraction and aortic stenosis
ConclusionThe choice of THV in patients with severe AS and systolic dysfunction must be weighed on a case-by-case basis.
Source: Journal of Cardiac Surgery - November 15, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Ahmad Mustafa, Chad Kliger, Luigi Pirelli, Arber Kodra, Denny Wang, Priyanka Singh, Paley Arnone, Apurva Patel, Shangyi Liu, Efstathia Mihelis, Elana Koss, Sean Wilson, Gregory Maniatis, Mohammed Imam, Puneet Gandotra, Robert Kalimi, Azhar Tags: ORIGINAL ARTICLE Source Type: research

Basal bodies bend in response to ciliary forces
Mol Biol Cell. 2022 Oct 26:mbcE22100468T. doi: 10.1091/mbc.E22-10-0468-T. Online ahead of print.ABSTRACTMotile cilia beat with an asymmetric waveform consisting of a power stroke that generates a propulsive force and a recovery stroke that returns the cilium back to the start. Cilia are anchored to the cell cortex by basal bodies (BBs) that are directly coupled to the ciliary doublet MTs. We find that, consistent with ciliary forces imposing on BBs, bending patterns in BB triplet MTs are responsive to ciliary beating. BB bending varies as environmental conditions change the ciliary waveform. Bending occurs where striated f...
Source: Mol Biol Cell - October 26, 2022 Category: Molecular Biology Authors: Anthony D Junker Louis G Woodhams Adam W J Soh Eileen T O'Toole Philip V Bayly Chad G Pearson Source Type: research

Selective Sinus Replacement for Aortic Root Aneurysm: Durable Approach in Selected Patients
CONCLUSIONS: For patients with sinus of Valsalva or asymmetric root aneurysm, SSR is associated with excellent operative outcomes, and mid-term follow-up suggests the technique is durable. Longer-term follow-up is needed to confirm continued stability of the aortic root.PMID:35872034 | DOI:10.1016/j.athoracsur.2022.05.071
Source: The Annals of Thoracic Surgery - July 25, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Andrew M Vekstein Charles M Wojnarski E Hope Weissler Adam R Williams Ryan P Plichta Jacob N Schroder G Chad Hughes Source Type: research

Open arch surgery in the redo setting. Contemporary outcomes
CONCLUSIONS: In this modern single-institution series, a systematic approach to redo-arch repair yields excellent operative outcomes and late aorta-specific survival. Reduced late overall survival reflects the comorbidity burden of this population. Open reconstruction continues to play an important role in reoperative arch repair in the modern era.PMID:35621063 | DOI:10.23736/S0021-9509.22.12388-8
Source: The Journal of Cardiovascular Surgery - May 27, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Andrew M Vekstein G Chad Hughes Edward P Chen Source Type: research