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Specialty: General Medicine
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Total 136 results found since Jan 2013.

Alcohol consumption and risk of cardiovascular outcomes and bleeding in patients with established atrial fibrillation
CMAJ. 2021 Jan 25;193(4):E117-E123. doi: 10.1503/cmaj.200778.ABSTRACTBACKGROUND: Little is known about the association between alcohol consumption and risk of cardiovascular events in patients with established atrial fibrillation (AF). The main aim of the current study was to investigate the associations of regular alcohol intake with incident stroke or systemic embolism in patients with established AF.METHODS: To assess the association between alcohol consumption and cardiovascular events in patients with established AF, we combined data from 2 comparable prospective cohort studies that followed 3852 patients with AF for ...
Source: Canadian Medical Association Journal - March 5, 2021 Category: General Medicine Authors: Philipp Reddiess Stefanie Aeschbacher Pascal Meyre Michael Coslovsky Michael K ühne Nicolas Rodondi Oliver Baretella J ürg H Beer Richard Kobza Giorgio Moschovitis Marcello Di Valentino Cyrill M üller Fabienne Steiner Leo H Bonati Christian Sticherling Source Type: research

Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Valve Stenosis at Low Surgical Risk: A Health Technology Assessment.
Conclusions: Both TAVI (transfemoral route) and SAVR resulted in improved patient symptoms and quality of life during the 1 year of follow-up. The TAVI procedure is less invasive and resulted in greater symptom improvement and quality of life than SAVR 30 days after surgery. The TAVI procedure also resulted in a small improvement in mortality and disabling stroke at 30 days. At 1 year, TAVI and SAVR were similar with regard to mortality, although TAVI may result in a slightly lower risk of disabling stroke. According to the study authors, longer follow-up is needed to better understand how long TAVI valves last and to draw...
Source: Ontario Health Technology Assessment Series - November 27, 2020 Category: General Medicine Tags: Ont Health Technol Assess Ser Source Type: research

Automated CT Perfusion Imaging to Aid in the Selection of Patients With Acute Ischemic Stroke for Mechanical Thrombectomy: A Health Technology Assessment.
Conclusions: Automated CT perfusion imaging has an acceptable sensitivity and specificity for detecting brain areas that have been affected by stroke. In patients selected for mechanical thrombectomy using automated CT perfusion imaging, there was significant improvement in functional independence. Mechanical thrombectomy informed by automated CT perfusion imaging is likely to be cost-effective. We estimate that publicly funding automated CT perfusion imaging in Ontario would result in additional costs of $1.3 million in year 1 and $0.9 million per year thereafter. PMID: 33240454 [PubMed - in process]
Source: Ontario Health Technology Assessment Series - November 27, 2020 Category: General Medicine Tags: Ont Health Technol Assess Ser Source Type: research

Occult cancer diagnosed following acute ischemic stroke.
Authors: Rioux B, Keezer MR, Gioia LC PMID: 32900764 [PubMed - in process]
Source: Canadian Medical Association Journal - September 10, 2020 Category: General Medicine Tags: CMAJ Source Type: research

Canadian Stroke Best Practice Recommendations, seventh edition: acetylsalicylic acid for prevention of vascular events.
Authors: Wein T, Lindsay MP, Gladstone DJ, Poppe A, Bell A, Casaubon LK, Foley N, Coutts SB, Cox J, Douketis J, Field T, Gioia L, Habert J, Lang E, Mehta SR, Papoushek C, Semchuk W, Sharma M, Udell JA, Lawrence S, Mountain A, Gubitz G, Dowlatshahi D, Simard A, de Jong A, Smith EE, Heart and Stroke Foundation of Canada in collaboration with the Canadian Stroke Consortium PMID: 32392513 [PubMed - as supplied by publisher]
Source: Canadian Medical Association Journal - May 12, 2020 Category: General Medicine Tags: CMAJ Source Type: research

Missing deadly etiologies in stroke triage: "What else could this be?"
Authors: Ganesh A, Varma M PMID: 32122980 [PubMed - in process]
Source: Canadian Medical Association Journal - March 5, 2020 Category: General Medicine Tags: CMAJ Source Type: research

In a First, Doctors Use Robotics to Treat Brain Aneurysm
FRIDAY, Feb. 21, 2020 -- Canadian doctors who conducted the first robotic surgery to treat a brain aneurysm say the approach could boost the availability and precision of lifesaving stroke care. Use of the technology could also be a first step...
Source: Drugs.com - Daily MedNews - February 21, 2020 Category: General Medicine Source Type: news

Electrical versus pharmacological cardioversion for emergency department patients with acute atrial fibrillation (RAFF2): a partial factorial randomised trial
This study is registered at ClinicalTrials.gov, number NCT01891058.FindingsBetween July 18, 2013, and Oct 17, 2018, we enrolled 396 patients, and none were lost to follow-up. In the drug–shock group (n=204), conversion to sinus rhythm occurred in 196 (96%) patients and in the shock-only group (n=192), conversion occurred in 176 (92%) patients (absolute difference 4%; 95% CI 0–9; p=0·07). The proportion of patients discharged home was 97% (n=198) versus 95% (n=183; p=0·60). 106 (52%) patients in the drug–shock group converted after drug infusion only. No patients had serious adverse events in follow-up. The differen...
Source: The Lancet - January 31, 2020 Category: General Medicine Source Type: research

Prescribing of oral anticoagulants in the emergency department and subsequent long-term use by older adults with atrial fibrillation.
Authors: Atzema CL, Jackevicius CA, Chong A, Dorian P, Ivers NM, Parkash R, Austin PC Abstract BACKGROUND: Patients with atrial fibrillation frequently seek emergency care. Rates of guideline-concordant oral anticoagulant therapy for stroke prevention are suboptimal in the community. We assessed the association between prescribing of oral anticoagulants in the emergency department (relative to referral to a longitudinal care provider for treatment initiation) and long-term use of oral anticoagulants. METHODS: This retrospective cohort study performed at 15 hospitals in Ontario, Canada, involved patients aged 65...
Source: Canadian Medical Association Journal - December 11, 2019 Category: General Medicine Tags: CMAJ Source Type: research

Thrombotic thrombocytopenic purpura masquerading as a stroke in a young man.
Authors: Doig CJ, Girard L, Jenkins D PMID: 31767706 [PubMed - in process]
Source: Canadian Medical Association Journal - November 27, 2019 Category: General Medicine Tags: CMAJ Source Type: research

Association of predicted lean body mass and fat mass with cardiovascular events in patients with type 2 diabetes mellitus.
Authors: Xing Z, Tang L, Chen J, Pei J, Chen P, Fang Z, Zhou S, Hu X Abstract BACKGROUND: Previous studies have found that predicted fat mass and lean body mass may act differently on adverse events. However, the cardiovascular prognostic value of lean body mass and fat mass in patients with type 2 diabetes mellitus (T2DM) has not yet been investigated. We sought to investigate the relation between predicted lean body mass or fat mass and the risk of cardiovascular disease in patients with T2DM. METHODS: We conducted a post hoc analysis of data from the Action to Control Cardiovascular Risk in Diabetes (ACCORD)...
Source: Canadian Medical Association Journal - September 25, 2019 Category: General Medicine Tags: CMAJ Source Type: research

For Seniors, ' Silent Strokes ' Are Common Post-Surgery Threat: Study
MONDAY, Aug. 26, 2019 -- Silent strokes are common in seniors who have had surgery, and may double their risk of mental decline within a year, a Canadian study reports. While an obvious (or " overt " ) stroke often causes symptoms such as weakness in...
Source: Drugs.com - Daily MedNews - August 26, 2019 Category: General Medicine Source Type: news

Value of routine echocardiography in the management of stroke.
Abstract BACKGROUND: Transthoracic echocardiography is routinely performed in patients with stroke or transient ischemic attack (TIA) to help plan secondary stroke management, but recent data evaluating its usefulness in this context are lacking. We sought to evaluate the value of echocardiography for identifying clinically actionable findings for secondary stroke prevention. METHODS: We conducted a multicentre cohort study of patients admitted to hospital with stroke or TIA between 2010 and 2015 at 2 academic hospitals in Toronto, Ontario, Canada. Clinically actionable echocardiographic findings for secondar...
Source: cmaj - August 5, 2019 Category: General Medicine Authors: Fralick M, Goldberg N, Rohailla S, Guo Y, Burke MJ, Lapointe-Shaw L, Kwan JL, Weinerman AS, Rawal S, Tang T, Razak F, Verma AA Tags: CMAJ Source Type: research

Platelet Indices as a Marker of Severity in Non-diabetic NonHypertensive Acute Ischemic Stroke Patients.
Conclusion: In patients of ischemic stroke platelet indices may be used for predicting severity of motor deficit. Although larger sample size and multivariate analysis is required before this can be used regularly in clinical practice. PMID: 31325260 [PubMed - in process]
Source: Journal of the Association of Physicians of India - July 22, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

15 Minutes Matters With Strokes
THURSDAY, July 18, 2019 -- Just 15 minutes can make a difference when someone is struck by a stroke, new research suggests. The study included more than 6,700 patients in the United States and Canada who suffered an ischemic stroke (blocked blood...
Source: Drugs.com - Daily MedNews - July 18, 2019 Category: General Medicine Source Type: news