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Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas)
ConclusionThis study expands the knowledge of stroke epidemiology in Brazil, a middle-income country with enormous socioeconomic and cultural diversity. The discrepancy observed regarding the impact of stroke in patients from Joinville and Sobral highlights the need to improve the strategic allocation of resources to meet the health priorities in each location.
Source: Frontiers in Neurology - September 15, 2022 Category: Neurology Source Type: research

Role of FAK signaling in chagasic cardiac hypertrophy.
Abstract Cardiac hypertrophy and dysfunction are a significant complication of chronic Chagas disease, with heart failure, stroke, and sudden death related to disease progression. Thus, understanding the signaling pathways involved in the chagasic cardiac hypertrophy may provide potential targets for pharmacological therapy. Herein, we investigated the implication of focal adhesion kinase (FAK) signaling pathway in triggering hypertrophic phenotype during acute and chronic T. cruzi infection. C57BL/6 mice infected with T. cruzi (Brazil strain) were evaluated for electrocardiographic (ECG) changes, plasma levels of...
Source: Braz J Infect Dis - September 11, 2020 Category: Infectious Diseases Authors: Tucci AR, Oliveira FOR, Lechuga GC, Oliveira GM, Eleuterio AC, Mesquita LB, Farani PSG, Britto C, Moreira OC, Pereira MCS Tags: Braz J Infect Dis Source Type: research

Prevalence of atrial fibrillation and stroke risk assessment based on telemedicine screening tools in a primary healthcare setting.
CONCLUSIONS: Our study highlights the importance of screening for AF in the primary care setting in Brazil and identifies important gaps in the treatment of AF in this population. PMID: 31320151 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - July 14, 2019 Category: Internal Medicine Authors: de Moraes ERFL, Cirenza C, Lopes RD, Carvalho AC, Guimaraes PO, Rodrigues AAE, de Paola AAV Tags: Eur J Intern Med Source Type: research

Rationale and design of the First Brazilian Cardiovascular Registry of Atrial Fibrillation: The RECALL study
This study will provide important information about demographics, practice patterns, treatments, and associated outcomes in patients with AF. The results of this registry will also allow Brazilian data to be put in perspective with other AF registries across the world and provide opportunities to improve care of patients with AF in Brazil.
Source: American Heart Journal - March 9, 2016 Category: Cardiology Source Type: research