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Total 534 results found since Jan 2013.

Arterial Stiffness and Indices of Left Ventricular Diastolic Dysfunction in Patients with Embolic Stroke of Undetermined Etiology.
Conclusions: Increased arterial stiffness and indices of diastolic dysfunction as well as a higher NT-proBNP level are significantly associated with ESUS. These parameters require further scrutiny over time to understand their impact on the development of symptomatic heart failure. The ClinicalTrials.gov identifier is NCT03377465. PMID: 31612072 [PubMed - in process]
Source: Disease Markers - October 17, 2019 Category: Laboratory Medicine Tags: Dis Markers Source Type: research

The Characteristics of Patients With Possible Transient Ischemic Attack and Minor Stroke in the Hunter and Manning Valley Regions, Australia (the INSIST Study)
Conclusion: This study provides the first contemporary data on TIAMS or TIAMS-mimics in Australia. Community and health provider education is required to address the under-use of anticoagulation therapy in patients with known AF, possibly inappropriate use of antiplatelet therapy and possibly inappropriate discontinuation of antiplatelet or anticoagulation therapy.
Source: Frontiers in Neurology - May 14, 2020 Category: Neurology Source Type: research

Regional Differences in Early BP Management After Acute Ischemic Stroke in the ENCHANTED International Randomized Controlled Trials
Conclusion: Regional variations in early BP management in acute stroke translated into differences in early BP control parameters.
Source: Frontiers in Neurology - August 27, 2021 Category: Neurology Source Type: research

Treatment with Multiple Therapeutic Classes of Medication is Associated with Survival after Stroke
Conclusion: Treatment with all three classes of guideline-recommended medications within 90 days post-discharge was associated with better survival. Ongoing efforts are required to ensure optimal pharmacological intervention for secondary prevention of stroke.
Source: Neuroepidemiology - November 10, 2021 Category: Epidemiology Source Type: research

A Multicentre Study Comparing Cerebrovascular Disease Profiles in Pacific Islander and Caucasian Populations Presenting with Stroke and Transient Ischaemic Attack
Conclusion: Distinct cerebrovascular disease profiles are identifiable in PI-born patients who present with TIA or stroke symptoms in Australia. These may be used in the future to direct targeted approaches to stroke prevention and care in culturally and linguistically diverse populations.Neuroepidemiology
Source: Neuroepidemiology - December 1, 2021 Category: Epidemiology Source Type: research

Tenecteplase use in the management of acute ischemic stroke: Literature review and clinical considerations
CONCLUSION: Current clinical evidence shows that tenecteplase is not inferior to alteplase for the treatment of ischemic stroke and suggests that tenecteplase may have a superior safety profile. Furthermore, tenecteplase also has practical advantages in terms of its administration. This can potentially lead to a decrease in medication errors and improvement in door to thrombolytic time.PMID:35020806 | DOI:10.1093/ajhp/zxac010
Source: American Journal of Health-System Pharmacy : AJHP - January 12, 2022 Category: Drugs & Pharmacology Authors: Kirubel Hailu Chad Cannon Sarah Hayes Source Type: research

Real-world effectiveness of lipid-lowering medications on outcomes after stroke: potential implications of the new-user design
Introduction: Observational studies are increasingly being used to provide evidence on the real-world effectiveness of medications for preventing vascular diseases, such as stroke. We investigated whether the real-world effectiveness of treatment with lipid-lowering medications after ischemic stroke is affected by prevalent user bias. Methods: An observational cohort study of 90-day survivors of ischemic stroke, using person-level data from the Australian Stroke Clinical Registry (2012-2016; 45 hospitals) linked to administrative (pharmaceutical, hospital, death) records. Use of, and adherence to (proportion of days covered
Source: Neuroepidemiology - July 21, 2022 Category: Epidemiology Source Type: research

Using body cameras to quantify the duration of a Code Stroke and identify workflow issues: a continuous observation workflow time study
Conclusions Codes are time intensive. Time spent on decision-making was a relatively small component of the overall Code duration. Data from body cameras can provide granular data on all aspects of Code workflow to inform potential areas for improvement at individual centres.
Source: BMJ Open - January 25, 2023 Category: General Medicine Authors: Wong, J. Z. W., Park, P. S. W., Frost, T., Stephens, K., Newk-Fon Hey Tow, F. K., Garcia, P. G., Senanayake, C., Choi, P. M. C. Tags: Open access, Neurology Source Type: research

Carotid endarterectomy: the change in practice over 11  years in a stroke centre
ConclusionThe trends in CEA practice at our centre align with international trends and guidelines. This study provides a representative indicator of Australian hospital practice, and illustrates how evidence from research is translated into clinical care.
Source: ANZ Journal of Surgery - November 13, 2017 Category: Surgery Authors: Gabrielle T. W. Tse, Monique F. Kilkenny, Chris Bladin, Michael Grigg, Helen M. Dewey Tags: Original Article Source Type: research

Economic burden of stroke: a systematic review on post-stroke care
ConclusionThe highest PSC costs were observed in the USA, with rehabilitation services being the main cost driver. Due to diversity in reporting, it was not possible to conduct a detailed cost analysis addressing different segments of services. Further approaches should benefit from the advantages of administrative and claims data, focusing on inpatient/outpatient PSC cost and its predictors, assuring appropriate resource allocation.
Source: The European Journal of Health Economics - June 16, 2018 Category: Health Management Source Type: research

New Cochrane health evidence challenges belief that omega 3 supplements reduce risk of heart disease, stroke or death
New evidence published today shows there is little or no effect of omega 3 supplements on our risk of experiencing heart disease, stroke or death.Omega 3 is a type of fat. Small amounts of omega 3 fats are essential for good health, and they can be found in the food that we eat. The main types of omega 3 fatty acids are; alpha ­linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).  ALA is normally found in fats from plant foods, such as nuts and seeds (walnuts and rapeseed are rich sources). EPA and DHA, collectively called long chain omega 3 fats, are naturally found in fatty fish, such as s...
Source: Cochrane News and Events - July 16, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

“In Safe Hands” – A costly integrated care program with limited benefits in stroke unit care
Publication date: Available online 6 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Sheila Jala, Sarah Giaccari, Melissa Passer, Carin Bertmar, Susan Day, Dayna Griffith, Martin KrauseAbstractGiven reported favourable outcomes of accountable care unit models of health care delivery (Taylor et al., 2017; Stein et al., 2015; Kara et al., 2015), the Clinical Excellence Commission of NSW has embraced “In Safe Hands” (ISH) to enhance coordination of care. ISH embraces the structured interdisciplinary bedside round (SIBR) component, for which reported outcomes include reduced length of stay (Taylor et al., 2...
Source: Journal of Clinical Neuroscience - November 6, 2018 Category: Neuroscience Source Type: research

Help-seeking and people with aphasia who have mood problems after stroke: perspectives of speech-language pathologists.
CONCLUSIONS & IMPLICATIONS: SLPs report both universal barriers to help-seeking and those specific to their clients with aphasia and attempts to overcome these; however, there appears to be a dearth of accessible mental health services for people with aphasia known to SLPs, including psychological/counselling professionals who are skilled in communicating with people with aphasia. Health professionals working within and across post-stroke and mental health services should recognize that people with post-stroke aphasia are susceptible to a decline in mental health, are amenable to formal (and tailored) psychological sup...
Source: International Journal of Language and Communication Disorders - June 16, 2019 Category: Speech-Language Pathology Authors: Ryan B, Bohan J, Kneebone I Tags: Int J Lang Commun Disord Source Type: research

Effect of occupational therapy home visit discharge planning on participation after stroke: protocol for the HOME Rehab trial
This study is approved by the Alfred Health Human Research Ethics Committee and site-specific ethics approval has been obtained at all participating sites. Results of the main trial and the secondary endpoint of cost-effectiveness will be submitted for publication in peer-reviewed journals Trial registration number ACTRN12618001360202
Source: BMJ Open - July 5, 2021 Category: General Medicine Authors: Lannin, N. A., Clemson, L., Drummond, A., Stanley, M., Churilov, L., Laver, K., O'Keefe, S., Cameron, I., Crotty, M., Usherwood, T., Andrew, N. E., Jolliffe, L., Cadilhac, D. A. Tags: Open access, Rehabilitation medicine Source Type: research

Patient suitability for free water protocols in acute stroke and general medicine: a qualitative study of clinician perceptions
CONCLUSIONS & IMPLICATIONS: Despite the benefits of FWPs in other settings, in acute stroke and general medicine, clinicians erred on the side of safety and, in most cases, would not implement an FWP. Future clinical research is needed to systematically design high-quality and feasible clinical trials to determine the benefits and safety of FWPs for patients with dysphagia in these settings. This would lay the foundations for guidelines to support the complex clinical decision-making regarding patient suitability for FWPs.WHAT THIS PAPER ADDS: What is already known on the subject FWPs are an alternate management strategy f...
Source: International Journal of Language and Communication Disorders - March 23, 2022 Category: Speech-Language Pathology Authors: Joanne Murray Shannon Maloney Kaitlyn Underdown Sebastian Doeltgen Source Type: research